TINGTING LIU#, XIANGRUI KONG#, JIANSHE WEI*
BIOCELL, Vol.48, No.12, pp. 1735-1749, 2024, DOI:10.32604/biocell.2024.056272
- 30 December 2024
Abstract Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. In recent times, an elevated risk of Parkinson’s disease (PD) development among individuals with T2DM has become evident. However, the molecular mechanisms that underpin the interplay between T2DM and the pathogenesis of PD remain to be elucidated. Nevertheless, recent epidemiological studies have underscored several shared molecular pathways that are crucial for normal cellular function and are also associated with the progression and etiology of both T2DM and PD. This review encapsulates some of the shared pathophysiological mechanisms, including genetic risk factors, More >