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    ARTICLE

    Calcium supplementation in colorectal cancer prevention: A systematic meta-analysis of adverse events

    XUE MEI LUO1, SHAHANAVAJ KHAN2,3,4,*, ABDUL MALIK2, FAHAD M. ALDAKHEEL5, ANIS AHMAD CHAUDHARY6, SHOUKI BAZARBASHI7, FATEMEH TABATABAIE8

    BIOCELL, Vol.46, No.3, pp. 759-767, 2022, DOI:10.32604/biocell.2022.016586 - 18 November 2021

    Abstract Despite the multiple systematic reviews and meta-analyses accumulating evidence on the preventive effect of calcium supplementation for colorectal cancer, most of the associated adverse effects are not systematically analyzed. The aim of the study is evaluating adverse events associated with calcium supplementation for colorectal cancer prevention through a systematic meta-analysis. We searched Medline, PubMed Central, EMBASE (Excerpta Medica database), Scopus, Cochrane Central Register of Controlled Trials, and Web of Science published in English from database inception up to 31 July 2019. In the current systematic meta-analysis, we included human studies (including cohort studies, clinical trials,… More >

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