RAFAEL SCAF DE MOLON1,2, MARTA MARIA ALVES PEREIRA2, ERICA DORIGATTI DE AVILA2
BIOCELL, Vol.46, No.5, pp. 1151-1156, 2022, DOI:10.32604/biocell.2022.018026
- 06 January 2022
Abstract It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix (ECM) that may affect cell behaviors. In nature, ECM is a heterogeneous three-dimensional superstructure formed by three major components, glycosaminoglycan, glycoconjugate, and protein, that anchors cellular compartments in tissues and regulates the function and the behavior of cells. Changes in the biointerface alter the quality of ECM and morphology through cell surface receptors, which, in turn, enable it to trigger specific cell signaling and different cellular responses. In fact, a number of strategies have been used to More >