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    ARTICLE

    Analytical and Numerical Methods to Study the MFPT and SR of a Stochastic Tumor-Immune Model

    Ying Zhang1, Wei Li1,*, Guidong Yang1, Snezana Kirin2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2177-2199, 2024, DOI:10.32604/cmes.2023.030728 - 15 December 2023

    Abstract The Mean First-Passage Time (MFPT) and Stochastic Resonance (SR) of a stochastic tumor-immune model with noise perturbation are discussed in this paper. Firstly, considering environmental perturbation, Gaussian white noise and Gaussian colored noise are introduced into a tumor growth model under immune surveillance. As follows, the long-time evolution of the tumor characterized by the Stationary Probability Density (SPD) and MFPT is obtained in theory on the basis of the Approximated Fokker-Planck Equation (AFPE). Herein the recurrence of the tumor from the extinction state to the tumor-present state is more concerned in this paper. A more… More >

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