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  • Open Access

    PROCEEDINGS

    Additive Manufacturing of Stents for the Coarctation of Aorta

    Yi Huang1, Giovanni Biglino1, Fengyuan Liu2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.013295

    Abstract Coarctation of aorta (CoA) is one of the congenital heart diseases with a proportion of 5% to 10%, which has a prevalence of four per 10,000 babies. As the most common cardiac defect missed at routine physical exams, CoA has a high undiagnosed rate of 60% to 80% in newborns before hospital discharge. The insertion of bare metal stents (BMS) with balloon dilatation is the useful method to reopen the narrow area of aorta. However, the stented vessel has a fixed diameter and cannot grow with the age, resulting in a relative restenosis and frequent… More >

  • Open Access

    PROCEEDINGS

    Microstructures and Nanomechanical Properties of Additively Manufactured Metallic Stents

    Enzoh Langi1, Liguo Zhao2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.010163

    Abstract Additive manufacturing emerges as an innovative technology to fabricate medical stents used to treat blocked arteries. However, there is a lack of study of underlying microstructure and mechanical properties of additively manufactured stent. In this work, additively manufactured 316L stainless steel stent was investigated, with electrochemical polishing being used to improve the surface finish. Microstructural characterisation was carried out using optical microscopy, scanning electron microscopy, and electron backscatter diffraction. The hardness and elastic modulus were measured using Berkovich nanoindentation, with an emphasis on the effect of grain orientation. In addition, spherical nanoindentation was used to… More >

  • Open Access

    REVIEW

    Ductus Arteriosus Stent Compared with Surgical Shunt for Infants with Ductal-Dependent Pulmonary Blood Flow: A Systematic Review and Meta-Analysis

    Sibao Wang, Silin Pan*, Gang Luo, Zhixian Ji, Na Liu

    Congenital Heart Disease, Vol.17, No.1, pp. 45-60, 2022, DOI:10.32604/CHD.2022.016332 - 26 October 2021

    Abstract The aim of this study was to perform a systematic review and meta-analysis to evaluate the safety and efficacy of ductus arteriosus stent (DAS) compared with surgical systemic-pulmonary artery shunt (SPS) in patients with ductal-dependent pulmonary blood flow. A literature search was conducted in PubMed, Embase, and the Cochrane Library databases from their inception to December 2020. Two reviewers independently screened the articles, evaluated the quality of the articles, and collected the data. Meta-analyses were conducted using fixed and random effects models. We used the I-square (I2 ) test to examine heterogeneity and the funnel plot… More >

  • Open Access

    ARTICLE

    Pulmonary artery interventions after the arterial switch operation: Unique and significant risks

    Jesse Lee, Doaa Abdullah Shahbah, Howaida El‐Said, Rodrigo Rios, Kanishka Ratnayaka, John Moore

    Congenital Heart Disease, Vol.14, No.2, pp. 288-296, 2019, DOI:10.1111/chd.12726

    Abstract Background: In the modern era, results of the arterial switch operation (ASO) for transposition of the great arteries are excellent. However, because of the LeCompte maneuver, there may be a propensity for development of pulmonary artery stenosis. We encountered atypical complications of pulmonary artery stenting in patients after the ASO, including aorto‐pulmonary fistula and coronary compression.
    Methods: We performed a 10‐year retrospective review of catheterizations per‐ formed in patients after ASO in our institution with a focus on adverse events.
    Results: Diagnostic and interventional catheterizations were performed in 47 pa‐ tients. In 29 patients, 37 interventional procedures performed,… More >

  • Open Access

    ARTICLE

    Effects of rotational culture on morphology, nitric oxide production and cell cycle of endothelial cells

    CHAOJUN TANG1, XUE WU1, LINQI YE1,2, XIANG XIE1, GUIXUE WANG1*

    BIOCELL, Vol.36, No.3, pp. 97-104, 2012, DOI:10.32604/biocell.2012.36.097

    Abstract Devices for the rotational culture of cells and the study of biological reactions have been widely applied in tissue engineering. However, there are few reports exploring the effects of rotational culture on cell morphology, nitric oxide (NO) production, and cell cycle of the endothelial cells from human umbilical vein on the stent surface. This study focuses on these parameters after the cells are seeded on the stents. Results showed that covering of stents by endothelial cells was improved by rotational culture. NO production decreased within 24 h in both rotational and static culture groups. In More >

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