Feezan Ahmad¹, Xiaowei Tang¹, Jilei Hu^2,*, Mahmood Ahmad^3,4, Behrouz Gordan⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.1, pp. 455-487, 2023, DOI:10.32604/cmes.2023.025993

Abstract Slope stability prediction plays a significant role in landslide disaster prevention and mitigation. This paper’s reduced error pruning (REP) tree and random tree (RT) models are developed for slope stability evaluation and meeting the high precision and rapidity requirements in slope engineering. The data set of this study includes five parameters, namely slope height, slope angle, cohesion, internal friction angle, and peak ground acceleration. The available data is split into two categories: training (75%) and test (25%) sets. The output of the RT and REP tree models is evaluated using performance measures including accuracy (Acc), Matthews correlation coefficient (Mcc), precision… More >

Salvatore Brischetto^*, Roberto Torre, Domenico Cesare

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.3, pp. 2551-2594, 2023, DOI:10.32604/cmes.2023.026312

Abstract This new work aims to develop a full coupled thermomechanical method including both the temperature profile and displacements as primary unknowns of the model. This generic full coupled 3D exact shell model permits the thermal stress investigation of laminated isotropic, composite and sandwich structures. Cylindrical and spherical panels, cylinders and plates are analyzed in orthogonal mixed curved reference coordinates. The 3D equilibrium relations and the 3D Fourier heat conduction equation for spherical shells are coupled and they trivially can be simplified in those for plates and cylindrical panels. The exponential matrix methodology is used to find the solutions of a… More >

Jikang Xu^1,4, Ruichuan Li^1,2,*, Yi Cheng², Yanchao Li³, Junru Yang³, Chenyu Feng⁴, Xinkai Ding², Huazhong Zhang⁵

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.7, pp. 1817-1836, 2023, DOI:10.32604/fdmp.2023.022602

Abstract Electro-hydraulic proportional valve is the core control valve in many hydraulic systems used in agricultural and engineering machinery. To address the problem related to the large throttling losses and poor stability typically associated with these valves, here, the beneficial effects of a triangular groove structure on the related hydraulic response are studied. A mathematical model of the pressure compensation system based on the power-bond graph method is introduced, and the AMESim software is used to simulate its response. The results show that the triangular groove structure increases the jet angle and effectively compensates for the hydrodynamic force. The steady-state differential… More > Graphic Abstract

YUNG-SUNG YEH^1,2,3, HSIANG-LIN TSAI^4,5, YEN-CHENG CHEN^4,6, WEI-CHIH SU^4,6, PO-JUNG CHEN^4,6, TSUNG-KUN CHANG^4,6,7, CHING-CHUN LI⁴, CHING-WEN HUANG^4,5, JAW-YUAN WANG^{4,5,6,8,9,10,*}

Oncology Research, Vol.30, No.2, pp. 65-76, 2022, DOI:10.32604/or.2022.026659

Abstract The controversial outcomes in patients with metastatic colorectal cancer (mCRC) highlight the need for developing effective systemic neoadjuvant treatment strategies to improve clinical results. The optimal treatment cycles in patients with mCRC for metastasectomy remain undefined. This retrospective study compared the efficacy, safety, and survival of cycles of neoadjuvant chemotherapy/targeted therapy for such patients. Sixty-four patients with mCRC who received neoadjuvant chemotherapy/targeted therapy following metastasectomy were enrolled between January 2018 and April 2022. Twenty-eight patients received 6 cycles of chemotherapy/targeted therapy, whereas 36 patients received ≥7 cycles (median, 13; range, 7–20). Clinical outcomes, including response, progression-free survival (PFS), overall survival… More >

Mohamed Elnagi¹, Salah Kamel², Abdelhady Ramadan², Mohamed F. Elnaggar^3,4,*

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5229-5250, 2023, DOI:10.32604/cmc.2023.032469

Abstract Renewable energy sources are gaining popularity, particularly photovoltaic energy as a clean energy source. This is evident in the advancement of scientific research aimed at improving solar cell performance. Due to the non-linear nature of the photovoltaic cell, modeling solar cells and extracting their parameters is one of the most important challenges in this discipline. As a result, the use of optimization algorithms to solve this problem is expanding and evolving at a rapid rate. In this paper, a weIghted meaN oF vectOrs algorithm (INFO) that calculates the weighted mean for a set of vectors in the search space has… More >

USAMA SHARIF AHMAD, KARTHIK SARAVANAN, HONG WAN^*

Oncology Research, Vol.29, No.6, pp. 377-391, 2021, DOI:10.32604/or.2022.026085

Abstract The Yes-associated protein (YAP) is a downstream effector of the Hippo pathway and acts as a key transcription co-factor to regulate cell migration, proliferation, and survival. The Hippo pathway is evolutionarily conserved and controls tissue growth and organ size. Dysregulation and heterogeneity of this pathway are found in cancers, including oral squamous cell carcinoma (OSCC), leading to overexpression of YAP and its regulated proliferation machinery. The activity of YAP is associated with its nuclear expression and is negatively regulated by the Hippo kinase-mediated phosphorylation resulting in an induction of its cytoplasmic translocation. This review focuses on the role of YAP… More >

Xingye Xu¹, Haiyan Song^1,2,*, Lijun Wang^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.1, pp. 275-292, 2023, DOI:10.32604/cmes.2022.022637

Abstract The sandwich structure of cushioning packaging has an important influence on the cushioning performance. Mathematical fractal theory is an important graphic expression. Based on Hilbert fractal theory, a new sandwich structure was designed. The generation mechanism and recurrence formula of the Hilbert fractal were expressed by Lin’s language, and the second-order Hilbert sandwich structure was constructed from thermoplastic polyurethane. The constitutive model of the hyperelastic body was established by using the finite element method. With the unit mass energy absorption as the optimization goal, the fractal sandwich structure was optimized, and the best result was obtained when the order was… More >

Francesco Tornabene^*, Matteo Viscoti, Rossana Dimitri

CMES-Computer Modeling in Engineering & Sciences, Vol.134, No.2, pp. 1393-1468, 2023, DOI:10.32604/cmes.2022.022237

Abstract In the present manuscript, a Layer-Wise (LW) generalized model is proposed for the linear static analysis of doublycurved shells constrained with general boundary conditions under the influence of concentrated and surface loads. The unknown field variable is modelled employing polynomials of various orders, each of them defined within each layer of the structure. As a particular case of the LW model, an Equivalent Single Layer (ESL) formulation is derived too. Different approaches are outlined for the assessment of external forces, as well as for non-conventional constraints. The doubly-curved shell is composed by superimposed generally anisotropic laminae, each of them characterized… More >

Francesco Tornabene^*, Matteo Viscoti, Rossana Dimitri

CMES-Computer Modeling in Engineering & Sciences, Vol.133, No.3, pp. 719-798, 2022, DOI:10.32604/cmes.2022.022210

Abstract The article proposes an Equivalent Single Layer (ESL) formulation for the linear static analysis of arbitrarily-shaped shell structures subjected to general surface loads and boundary conditions. A parametrization of the physical domain is provided by employing a set of curvilinear principal coordinates. The generalized blending methodology accounts for a distortion of the structure so that disparate geometries can be considered. Each layer of the stacking sequence has an arbitrary orientation and is modelled as a generally anisotropic continuum. In addition, re-entrant auxetic three-dimensional honeycomb cells with soft-core behaviour are considered in the model. The unknown variables are described employing a… More > Graphic Abstract

He Gong^1,2,3, Zilian Wang^1,3, Zhiqiang Cheng⁴, Lin Chen^1,3, Haohong Pan^1,3, Daming Zhang², Tianli Hu^1,3,*, Thobela Louis Tyasi⁵

CMC-Computers, Materials & Continua, Vol.73, No.3, pp. 4971-4980, 2022, DOI:10.32604/cmc.2022.029433

Abstract Flexible strain sensor has attracted much attention because of its potential application in human motion detection. In this work, the prepared strain sensor was obtained by encapsulating electrospun carbonized sponge (CS) with room temperature vulcanized silicone rubber (RTVS). In this paper, the formation mechanism of conductive sponge was studied. Based on the combination of carbonized sponge and RTVS, the strain sensing mechanism and piezoresistive properties are discussed. After research and testing, the CS/RTVS flexible strain sensor has excellent fast response speed and stability, and the maximum strain coefficient of the sensor is 136.27. In this study, the self-developed CS/RTVS sensor… More >