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  • Open Access

    ARTICLE

    Performance Study of Dynamic Intake and Exhaust Façades in Hot and Dry Climates: Iraq Case Study

    S. M. Hosseinalipour*, S. Asiaei*, Ammar A. Hussain Al-Taee

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 747-767, 2024, DOI:10.32604/fhmt.2024.051541

    Abstract This paper is part of a series addressing the urgent need for effective technologies to reduce energy demand and mitigate climate impact. This study focused on the implementation and development of dynamic insulation technology for a sustainable and energy-efficient future in the region, especially in Iraq. The study assessed the energy efficiency of dynamic insulation technology by analyzing three wall models (static, dynamic, and modified) during the winter season. This paper expands the analysis to include a hot, dry summer scenario, providing valuable insights into the year-round performance of dynamic walls and enabling sustainable and More >

  • Open Access

    ARTICLE

    Gemcitabine Plus Vinorelbine as Second-Line Therapy in Patients With Metastatic Esophageal Cancer Previously Treated With Platinum-Based Chemotherapy

    Yue-shen Wang*1, Jing Tian†1, Yong Han, Shu-mei Han, Sheng-bin Shi

    Oncology Research, Vol.24, No.2, pp. 129-135, 2016, DOI:10.3727/096504016X14618564639213

    Abstract We evaluated the efficacy and feasibility of the combination of gemcitabine plus vinorelbine in patients with platinum-based chemotherapy-refractory esophageal cancer. We enrolled 35 patients who received gemcitabine plus vinorelbine as second-line treatment after platinum-based chemotherapy failure between May 2009 and April 2012. Dosage: gemcitabine 1,000 mg/m2 plus vinorelbine 25 mg/m2 ; all drugs were administered on days 1 and 8 of a 21-day cycle, and this was continued until failure or unacceptable toxicity. A total of 125 cycles of treatment were administered, and all patients received at least two cycles of treatment (two to five cycles;… More >

  • Open Access

    ARTICLE

    Regorafenib Plus FOLFIRI With Irinotecan Dose Escalated According to Uridine Diphosphate Glucuronosyltransferase 1A1 Genotyping in Patients With Metastatic Colorectal Cancer

    Cheng-Jen Ma*†‡, Ching-Wen Huang*‡§, Yung-Sung Yeh*†¶, Hsiang-Lin Tsai*§#**, Huang-Ming Hu††‡‡, I-Chen Wu††‡‡, Tian-Lu Cheng§§¶¶, Jaw-Yuan Wang*†‡§**¶¶

    Oncology Research, Vol.25, No.5, pp. 673-679, 2017, DOI:10.3727/97818823455816X14786040691928

    Abstract We analyzed the results of previously treated patients with metastatic colorectal cancer (mCRC) who received regorafenib plus FOLFIRI with the irinotecan dose escalation on the basis of uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) genotyping. Thirteen patients with previously treated mCRC were subjected to UGT1A1 genotyping between October 2013 and June 2015 and were administered regorafenib plus FOLFIRI with irinotecan dose escalation. Patients with UGT1A1*1/*1 and *1/*28 genotypes were administered 180 mg/m2 of irinotecan, whereas those with the UGT1A1*28/*28 genotype were administered 120 mg/m2 of irinotecan. For all patients, the irinotecan dose was increased by 30 mg/m2 every… More >

  • Open Access

    ARTICLE

    Activation of Vimentin Is Critical to Promote a Metastatic Potential of Cholangiocarcinoma Cells

    Waraporn Saentaweesuk*†‡, Norie Araki, Kulthida Vaeteewoottacharn*†, Atit Silsirivanit*†‡, Wunchana Seubwai†§, Chutima Talabnin, Kanha Muisuk§, Banchob Sripa†#, Sopit Wongkham*†, Seiji Okada**, Chaisiri Wongkham*†

    Oncology Research, Vol.26, No.4, pp. 605-616, 2018, DOI:10.3727/096504017X15009778205068

    Abstract Cholangiocarcinoma (CCA) is a highly metastatic tumor, and the majority of patients with CCA have a short survival time because there are no available effective treatments. Hence, a better understanding regarding CCA metastasis may provide an opportunity to improve the strategies for treatment. A comparison study between the highly metastatic cells and their parental cells is an approach to uncover the molecular mechanisms underlying the metastatic process. In the present study, a lung metastatic CCA cell line, KKU-214L5, was established by the in vivo selection of the tail vein-injected mouse model. KKU-214L5 cells possessed mesenchymal… More >

  • Open Access

    ARTICLE

    Novel Static Security and Stability Control of Power Systems Based on Artificial Emotional Lazy Q-Learning

    Tao Bao*, Xiyuan Ma, Zhuohuan Li, Duotong Yang, Pengyu Wang, Changcheng Zhou

    Energy Engineering, Vol.121, No.6, pp. 1713-1737, 2024, DOI:10.32604/ee.2023.046150

    Abstract The stability problem of power grids has become increasingly serious in recent years as the size of novel power systems increases. In order to improve and ensure the stable operation of the novel power system, this study proposes an artificial emotional lazy Q-learning method, which combines artificial emotion, lazy learning, and reinforcement learning for static security and stability analysis of power systems. Moreover, this study compares the analysis results of the proposed method with those of the small disturbance method for a stand-alone power system and verifies that the proposed lazy Q-learning method is able More >

  • Open Access

    ARTICLE

    Design and Performance Analysis of HMDV Dynamic Inertial Suspension Based on Active Disturbance Rejection Control

    Xiaofeng Yang1,3,4, Wei Wang1,3,4,*, Yujie Shen2,4, Changning Liu1,3,4, Tianyi Zhang1,4

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1485-1506, 2024, DOI:10.32604/cmes.2024.049837

    Abstract This paper addresses the impact of vertical vibration negative effects, unbalanced radial forces generated by the static eccentricity of the hub motor, and road excitation on the suspension performance of Hub Motor Driven Vehicle (HMDV). A dynamic inertial suspension based on Active Disturbance Rejection Control (ADRC) is proposed, combining the vertical dynamic characteristics of dynamic inertial suspension with the features of ADRC, which distinguishes between internal and external disturbances and arranges the transition process. Firstly, a simulation model of the static eccentricity of the hub motor is established to simulate the unbalanced radial electromagnetic force… More > Graphic Abstract

    Design and Performance Analysis of HMDV Dynamic Inertial Suspension Based on Active Disturbance Rejection Control

  • Open Access

    ARTICLE

    Influence of Confined Concrete Models on the Seismic Response of RC Frames

    Hüseyin Bilgin*, Bredli Plaku

    Structural Durability & Health Monitoring, Vol.18, No.3, pp. 197-222, 2024, DOI:10.32604/sdhm.2024.048645

    Abstract In this study, the influence of confined concrete models on the response of reinforced concrete structures is investigated at member and global system levels. The commonly encountered concrete models such as Modified Kent-Park, Saatçioğlu-Razvi, and Mander are considered. Two moment-resisting frames designed according to the pre-modern code are taken into consideration to reflect the example of an RC moment-resisting frame in the current building stock. The building is in an earthquake-prone zone located on Z3 Soil Type. The inelastic response of the building frame is modelled by considering the plastic hinges formed on each beam… More >

  • Open Access

    ARTICLE

    Static Analysis Techniques for Fixing Software Defects in MPI-Based Parallel Programs

    Norah Abdullah Al-Johany1,*, Sanaa Abdullah Sharaf1,2, Fathy Elbouraey Eassa1,2, Reem Abdulaziz Alnanih1,2,*

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3139-3173, 2024, DOI:10.32604/cmc.2024.047392

    Abstract The Message Passing Interface (MPI) is a widely accepted standard for parallel computing on distributed memory systems. However, MPI implementations can contain defects that impact the reliability and performance of parallel applications. Detecting and correcting these defects is crucial, yet there is a lack of published models specifically designed for correcting MPI defects. To address this, we propose a model for detecting and correcting MPI defects (DC_MPI), which aims to detect and correct defects in various types of MPI communication, including blocking point-to-point (BPTP), nonblocking point-to-point (NBPTP), and collective communication (CC). The defects addressed by… More >

  • Open Access

    ARTICLE

    Experimental Novel Investigation of Electrostatic Charged Multi Walled Carbon Nanotubes Reinforced Epoxy Based Polymer Composite

    R. SARAVANAN*, A. SURESHBABU

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 43-54, 2020, DOI:10.32381/JPM.2020.37.1-2.4

    Abstract In this research work, multi walled carbon nanotubes (MWCNT) particulate filler of various (0.9, 1.2, 1.5, & 1.8 wt %) weight percentage was used along with epoxy resin. A novel method of distributing the MWCNT in epoxy had been employed to reduce the agglomeration problem by charging the MWCNT electrostatically. The electrostatic charged (MWCNT) and uncharged (MWCNT) were loaded on to matrix and then it was stirred by a mechanical mixer for 300 minutes continuously to achieve uniform distribution. The nano filler reinforced composite was fabricated by using hand layup method and mechanical testing (Tensile More >

  • Open Access

    ARTICLE

    Study of Galvanic Charging-Discharging Properties of Graphene Nanoplatelets Incorporated Epoxy-Carbon Fabric Composites

    HADIMANI SHIVAKUMAR1, GURUMURTHY G. D.1, BOMMEGOWDA K. B.2, S. PARAMESHWARA3

    Journal of Polymer Materials, Vol.40, No.1-2, pp. 93-103, 2023, DOI:10.32381/JPM.2023.40.1-2.8

    Abstract Polymer composites are increasing in demand in energy storage applications including in the electronic as well as electrical industries due to the ease of processing of these materials with associated advantages like light weight, corrosion resistance, and high mechanical strength. In this investigation, efforts are made to enhance the charging and discharging properties of epoxy/carbon fabric composite by the addition of graphene nanoplatelets (GNPs) into the epoxy/ carbon matrix. The performance of the composites with graphene platelets of 0.5 to 5 wt. % in epoxy were characterized and 1wt.% percolation threshold was observed poor performance… More >

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