HONGYANG LI^1,2, CHAN WANG⁴, SHIWEI LIU¹, YONGLONG GUO^1,3,4,*, JIANSU CHEN^1,3,4,*

BIOCELL, Vol.46, No.7, pp. 1705-1716, 2022, DOI:10.32604/biocell.2022.018442

Abstract Human adipose stem cells (hADSCs) are reliable sources for cell therapy. However, the clinical applications are limited by the decrease in activity during in vitro culture. We used a knockout serum replacement (KSR) medium, Eppendorf (EP) tube culture, and a simulated microgravity (SMG) culture system to establish hADSC spheroids. We found that hADSCs aggregated and formed spheroids in the KSR culture medium. The EP tube culture method revealed many biological cell characteristics, such as good cell viabilities, rough surfaces, polar growth, fusion phenomenon, and injectability. The findings show its advantages for hADSCs spherical cultures. When cultured in SMG, hADSC spheroids… More >

Yi W. Wan¹, Huan J. Keh²

CMES-Computer Modeling in Engineering & Sciences, Vol.74, No.2, pp. 109-138, 2011, DOI:10.3970/cmes.2011.074.109

Abstract The steady rotation of an axially symmetric particle about its axis of revolution normal to two plane walls at an arbitrary position between them in a viscous fluid is studied theoretically in the limit of small Reynolds number. The fluid is allowed to slip at the surface of the particle. A method of distribution of a set of spherical singularities along the axis of revolution inside a prolate particle or on the fundamental disk within an oblate particle is used to find the general solution for the fluid velocity distribution that satisfies the boundary conditions at the confining walls and… More >

Huan J. Keh¹, Yu C. Chang²

CMES-Computer Modeling in Engineering & Sciences, Vol.62, No.3, pp. 225-254, 2010, DOI:10.3970/cmes.2010.062.225

Abstract A theoretical study of the Stokes flow caused by a rigid particle of revolution translating axisymmetrically perpendicular to two parallel plane walls at an arbitrary position between them in a viscous fluid, which may slip at the particle surface, is presented. A method of distribution of a set of spherical singularities along the axis of revolution within a prolate particle or on the fundamental plane within an oblate particle is used to find the general solution of the fluid velocity field that satisfies the boundary conditions at the plane walls and at infinity. The slip condition on the particle surface… More >

A. Vukovic¹, P. Sewell¹, T. M. Benson¹

CMES-Computer Modeling in Engineering & Sciences, Vol.55, No.2, pp. 171-190, 2010, DOI:10.3970/cmes.2010.055.171

Abstract A fast and accurate method is developed for the analysis of a class of metal three-dimensional resonators with rotational symmetry. The analysis is formulated using the Body of Revolution approach and the Method of Analytical Regularization. This development is motivated by the need for three-dimensional analytical solvers that could enable fast and accurate analysis of photonic resonant structures which support very high Q whispering gallery modes and which are computationally challenging for numerical simulations. The paper outlines the formulation of the method and demonstrates the stability and the source of computation errors of the method. As a practical illustration, the… More >

Yi W. Wan¹, Huan J. Keh²

CMES-Computer Modeling in Engineering & Sciences, Vol.53, No.1, pp. 73-94, 2009, DOI:10.3970/cmes.2009.053.073

Abstract The problem of the rotation of a rigid particle of revolution about its axis in a viscous fluid is studied theoretically in the steady limit of low Reynolds number. The fluid is allowed to slip at the surface of the particle. A singularity method based on the principle of distribution of a set of spherical singularities along the axis of revolution within a prolate particle or on the fundamental plane within an oblate particle is used to find the general solution for the fluid velocity field that satisfies the boundary condition at infinity. The slip condition on the surface of… More >