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    REVIEW

    Progress in research on tumor microenvironment-based spatial omics technologies

    FANGMEI XIE1,#, NAITE XI1,#, ZEPING HAN1,#, WENFENG LUO1, JIAN SHEN1, JINGGENG LUO2, XINGKUI TANG2, TING PANG1, YUBING LV1, JIABING LIANG1, LIYIN LIAO1, HAOYU ZHANG1, YONG JIANG1, YUGUANG LI3,*, JINHUA HE1,*

    Oncology Research, Vol.31, No.6, pp. 877-885, 2023, DOI:10.32604/or.2023.029494 - 15 September 2023

    Abstract Spatial omics technology integrates the concept of space into omics research and retains the spatial information of tissues or organs while obtaining molecular information. It is characterized by the ability to visualize changes in molecular information and yields intuitive and vivid visual results. Spatial omics technologies include spatial transcriptomics, spatial proteomics, spatial metabolomics, and other technologies, the most widely used of which are spatial transcriptomics and spatial proteomics. The tumor microenvironment refers to the surrounding microenvironment in which tumor cells exist, including the surrounding blood vessels, immune cells, fibroblasts, bone marrow-derived inflammatory cells, various signaling More >

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