Oncology Research Editorial Office

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.077270 - 30 December 2025

Abstract This article has no abstract. More >

Shenghui Su, Yu Zeng, Jiaxin Chen, Xieping Dong^*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070558 - 30 December 2025

Abstract Background: Recent studies have shown glycerolipid metabolism played an essential role in multiple tumors, however, its function in osteosarcoma is unclear. This study aimed to explore the role of glycerolipid metabolism in osteosarcoma. Methods: We conducted bioinformatics analysis using data from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database and single-cell RNA sequencing. Least Absolute Shrinkage and Selection Operator (LASSO) regression was used to identify the Glycerolipid metabolism-related genes associated with the clinical outcome of osteosarcoma. Tumor-associated macrophages (TAMs) and their interactions with immune cells were examined through single-cell analysis and co-culture experiments.… More >

Kai Gui^1,#, Tianyi Yang^1,#, Chengying Xiong¹, Yue Wang¹, Zhiqiang He¹, Wuxian Li^2,3,*, Min Tang^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070143 - 30 December 2025

Abstract Objectives: The mechanism by which specific tumor subsets in colorectal cancer (CRC) use alternative metabolic pathways, particularly those modulated by hypoxia and fructose, to alter the tumor microenvironment (TME) remains unclear. This study aimed to identify these malignant subpopulations and characterize their intercellular signaling networks and spatial organization through an integrative multi-omics approach. Methods: Leveraging bulk datasets, single-cell RNA sequencing, and integrative spatial transcriptomics, we developed a prognostic model based on hypoxia-and fructose metabolism-related genes (HFGs) to delineate tumor cell subpopulations and their intercellular signaling networks. Results: We identified a specific subset of stanniocalcin-2 positive (STC2+)… More > Graphic Abstract

Shaojie Min¹, Yaxiao Luo¹, Kebing Liu¹, Qingyuan Gong², Yang Chen^1,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.073175 - 09 December 2025

Abstract User identity linkage (UIL) across online social networks seeks to match accounts belonging to the same real-world individual. This cross-platform mapping enables accurate user modeling but also raises serious privacy risks. Over the past decade, the research community has developed a wide range of UIL methods, from structural embeddings to multimodal fusion architectures. However, corresponding adversarial and defensive approaches remain fragmented and comparatively understudied. In this survey, we provide a unified overview of both mapping and anti-mapping methods for UIL. We categorize representative mapping models by learning paradigm and data modality, and systematically compare them… More >

Bing Zhang, Wenqi Shi^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.067470 - 09 December 2025

Abstract To address the challenge of low survival rates and limited data collection efficiency in current virtual probe deployments, which results from anomaly detection mechanisms in location-based service (LBS) applications, this paper proposes a novel virtual probe deployment method based on user behavioral feature analysis. The core idea is to circumvent LBS anomaly detection by mimicking real-user behavior patterns. First, we design an automated data extraction algorithm that recognizes graphical user interface (GUI) elements to collect spatio-temporal behavior data. Then, by analyzing the automatically collected user data, we identify normal users’ spatio-temporal patterns and extract their… More >

Qin Hu, Hongshan Kong^*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-31, 2026, DOI:10.32604/cmc.2025.069078 - 10 November 2025

Abstract To address the issues of frequent identity switches (IDs) and degraded identification accuracy in multi object tracking (MOT) under complex occlusion scenarios, this study proposes an occlusion-robust tracking framework based on face-pedestrian joint feature modeling. By constructing a joint tracking model centered on “intra-class independent tracking + cross-category dynamic binding”, designing a multi-modal matching metric with spatio-temporal and appearance constraints, and innovatively introducing a cross-category feature mutual verification mechanism and a dual matching strategy, this work effectively resolves performance degradation in traditional single-category tracking methods caused by short-term occlusion, cross-camera tracking, and crowded environments. Experiments… More >

Asal Jameel Khudhair^#, Amenah Dahim Abbood^#,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-31, 2026, DOI:10.32604/cmc.2025.068553 - 10 November 2025

Abstract Community detection is one of the most fundamental applications in understanding the structure of complicated networks. Furthermore, it is an important approach to identifying closely linked clusters of nodes that may represent underlying patterns and relationships. Networking structures are highly sensitive in social networks, requiring advanced techniques to accurately identify the structure of these communities. Most conventional algorithms for detecting communities perform inadequately with complicated networks. In addition, they miss out on accurately identifying clusters. Since single-objective optimization cannot always generate accurate and comprehensive results, as multi-objective optimization can. Therefore, we utilized two objective functions… More >

Noreen Fuentes¹, Janeth Ugang¹, Narcisan Galamiton¹, Suzette Bacus¹, Samantha Shane Evangelista², Fatima Maturan², Lanndon Ocampo^2,3,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-26, 2026, DOI:10.32604/cmc.2025.068104 - 10 November 2025

Abstract This study demonstrates a novel integration of large language models, machine learning, and multi-criteria decision-making to investigate self-moderation in small online communities, a topic under-explored compared to user behavior and platform-driven moderation on social media. The proposed methodological framework (1) utilizes large language models for social media post analysis and categorization, (2) employs k-means clustering for content characterization, and (3) incorporates the TODIM (Tomada de Decisão Interativa Multicritério) method to determine moderation strategies based on expert judgments. In general, the fully integrated framework leverages the strengths of these intelligent systems in a more systematic evaluation… More >

Chia-Hui Hou^*

International Journal of Mental Health Promotion, Vol.27, No.12, pp. 2007-2022, 2025, DOI:10.32604/ijmhp.2025.073748 - 31 December 2025

Abstract Objectives: With the rapid aging of populations worldwide, the long-term care (LTC) industry has become a critical arena for both social welfare and entrepreneurial development, particularly among women who play a leading role in caregiving enterprises. However, female LTC entrepreneurs often face emotional strain and limited social resources that affect their professional well-being. This study investigates the effects of psychological resilience and social capital on the well-being of female entrepreneurs in the long-term care (LTC) industry and examines the mediating role of entrepreneurial competence. Methods: A mixed-methods design was employed. Quantitative data were collected from 73… More >

Youngho Kim¹, Jonghwa Lee^2,*

International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1949-1960, 2025, DOI:10.32604/ijmhp.2025.072560 - 31 December 2025

Abstract Background: Shift-based occupations have been consistently linked to adverse psychological outcomes; however, limited research has examined how work schedule type and physical activity are jointly associated with mental health and job stress in public transportation employees, a population frequently exposed to irregular hours and safety-critical responsibilities. This study investigated the associations between work schedule type and physical activity with mental health indicators and job stress among Seoul Metro employees. Methods: A cross-sectional survey was administered to 298 full-time male employees of Seoul Metro. Participants were categorized by work schedule (shift vs. regular) and physical activity level… More >