Dandan Li*, Changjun He†, Junfeng Wang†, Yanbo Wang†, Jianlong Bu†, Xianglong Kong†, Dawei Sun†
Oncology Research, Vol.26, No.3, pp. 385-400, 2018, DOI:10.3727/096504017X14973124850905
Abstract Many studies have shown that downregulation of miR-138 occurs in a variety of cancers including non-small
cell lung cancer (NSCLC). However, the precise mechanisms of miR-138 in NSCLC have not been well clarified. In this study, we investigated the biological functions and molecular mechanisms of miR-138 in NSCLC
cell lines, discussing whether it could turn out to be a therapeutic biomarker of NSCLC in the future. In our
study, we found that miR-138 is downregulated in NSCLC tissues and cell lines. Moreover, the low level of
miR-138 was associated with increased expression of SOX4 in… More >
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