Fenglan Zhao¹, Jizhi Jin¹, Meng Yang¹, Franklin Eduardo Melo Santiago², Jianping Xue¹, Li Xu^3,*, Yongbo Duan^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.3, pp. 611-625, 2024, DOI:10.32604/phyton.2024.048295

Abstract

Seed germination with selenium (Se) is promising for producing Se-biofortified foods. Mungbean (Vigna radiata (L.) Wilczek) sprout is freshly eaten as a salad dressed with sauce, making it superior for Se biofortification. Since the Se safety range for the human body is extremely narrow, it is imperative to evaluate the genotypic responses of mungbean sprouts to Se. This study evaluated the Se enrichment capacity and interaction with flavonoids and antioxidant systems in sprouts of 20 mungbean germplasms. Selenium treatment was done by immersing mungbean seeds in 20 μM sodium selenite solution for 8 h. Afterward, the biomass, Se amounts, flavonoid… More >

ROGHAYEH GHORBANI¹, MAHMOUD GHARBAVI², ALI SHARAFI^3,4, ELHAM RISMANI⁵, HAMED REZAEEJAM⁶, YOUSEF MORTAZAVI^1,*, BEHROOZ JOHARI^3,*

Oncology Research, Vol.32, No.1, pp. 101-125, 2024, DOI:10.32604/or.2023.044741

Abstract In the present study, we investigated the synergistic effects of targeted methotrexate-selenium nanostructure containing Myc decoy oligodeoxynucleotides along with X-irradiation exposure as a combination therapy on LNCaP prostate cancer cells. Myc decoy ODNs were designed based on the promoter of Bcl-2 gene and analyzed by molecular docking and molecular dynamics assays. ODNs were loaded on the synthesized Se@BSA@Chi-MTX nanostructure. The physicochemical characteristics of nanostructures were determined by FTIR, DLS, UV-vis, TEM, EDX, in vitro release, and hemolysis tests. Subsequently, the cytotoxicity properties of them with and without X-irradiation were investigated by uptake, MTT, cell cycle, apoptosis, and scratch assays on… More > Graphic Abstract

Mojtaba Kordrostami¹, Ali Akbar Ghasemi-Soloklui¹, Mohammad Anwar Hossain^2,*, Mohammad Golam Mostofa^3,4,*

Phyton-International Journal of Experimental Botany, Vol.92, No.9, pp. 2713-2736, 2023, DOI:10.32604/phyton.2023.030372

Abstract Numerous plant species, particularly those that can accumulate selenium (Se) and silicon (Si), benefit from these essential micronutrients. Se and Si accumulation in plants profoundly affects several biochemical reactions in cells. Understanding how plants react to Se/Si enrichment is crucial for ensuring adequate dietary Se/Si intake for humans and animals and increasing plant tolerance to environmental stressors. Several studies have shown that Se/Si-enriched plants are more resistant to salinity, drought, extreme temperatures, UV radiation, and excess metalloids. The interplay between Se/Si in plants is crucial for maintaining growth and development under normal conditions while providing a critical defense mechanism against… More >

Ali Bandehagh^1,*, Zahra Dehghanian², Vahideh Gougerdchi¹, Mohammad Anwar Hossain^3,*

Phyton-International Journal of Experimental Botany, Vol.92, No.8, pp. 2301-2324, 2023, DOI:10.32604/phyton.2023.028586

Abstract The presence of selenium (Se) is not widely established as crucial for crops, although it is commonly recognized as an important nutrient for animals as well as humans. Even so, it is inevitably accepted that Se usually contributes positively to the life cycle of plants. Previous findings suggested that small amounts of Se seem to have a productive role in growth and production. As a result, Se is assumed to function in multiple ways, primarily by influencing a variety of biochemical and physiological functions. Also, Se also acts as a plant antioxidant and pro-oxidant and confers tolerance against different abiotic… More >

Armin Saed-Moucheshi^1,*, Elham Rezaei Mirghaed²

Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1921-1941, 2023, DOI:10.32604/phyton.2023.027810

Abstract

One of the main reasons of the annual reduction in plant production all around the world is the occurrence of abiotic stresses as a result of an unpredicted changes in environmental conditions. Abiotic stresses basically trigger numerous pathways related to oxygen free radicals’ generation resulting in a higher rate of reactive oxygen species (ROS) production. Accordingly, higher rate of oxygen free radicals than its steady state causes to oxidize various types of molecules and compartments within the plants’ cells and tissues. Oxidative stress is the result of high amount free radicals of oxygen interfering with different functions leading to undergo… More >

MIAOMIAO LI^1,#, ZILIN ZHENG^1,#, JUNYI KE¹, JIEYI LUO¹, FAN JIANG¹, YANXIA QU¹, BING ZHU², YINGHUA LI^2,*, LIANDONG ZUO^1,*

BIOCELL, Vol.47, No.6, pp. 1397-1405, 2023, DOI:10.32604/biocell.2023.027971

Abstract Background: Nano-selenium has been widely used in antiviral and anticancer therapy, and has the advantages of good targeting and low toxicity. For the first time, we combined male reproduction with nano-selenium to investigate its antioxidant effect. This study investigated the protective effect of lentinan functionalized selenium nanoparticles on oxidative stress injury of the hydrogen peroxide (H₂O₂)-induced Leydig cell line, TM3. Methods: The suitable concentration of nano-selenium treatment to promote cell proliferation was also discussed. The concentration of 4 μM could significantly promote the growth of TM3 cells. Oxidative stress damage was caused using an 800 μM concentration of hydrogen peroxide.… More >

Mohammad Reza Boorboori, Husen Qiu, Jieyun Liu, Haiyang Zhang^*

Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1873-1886, 2023, DOI:10.32604/phyton.2023.027924

Abstract Rice is an essential part of the human diet in most parts of the world; On the other hand, the industrialization of societies has led to pollution of the environment, including heavy metal contamination of soil and water, which negatively affects rice production and quality. Therefore, finding ways to increase the yield and quality of this strategic crop seems essential. Several studies have been conducted in recent decades to find effective and inexpensive solutions to reduce the adverse effects of heavy metals in rice fields. Due to the negative effect of cadmium pollution on rice quality and yield, the current… More >

Mufang Sun¹, Xinran Hui², Cuiling Tong³, Longyi Yuan², Dejian Zhang^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 851-860, 2023, DOI:10.32604/phyton.2022.025147

Abstract To study the effect of exogenous selenium on fruit quality in walnut (Juglans regia L.), 8-year-old walnut (Qingxiang) was taken as the research object. In the fruit expansion stage, 300 mg/L of sodium selenate, yeast selenium and sodium selenite solutions were applied on the leaf of walnut, and the selenium levels in leaves, pericarp and kernel were determined at the ripening stage. The fruit quality, mineral nutrient content, antioxidant enzyme activity, and related genes’ expression were analyzed. The results showed that the three exogenous selenium increased the selenium levels in leaves, pericarp and kernel of walnut. They also significantly increased… More >

SEHRISH ABBAS¹, BUSHRA UZAIR^1,*, MAISRA AZHAR BUTT¹, FARID MENAA², BARKAT A. KHAN^3,*

BIOCELL, Vol.47, No.2, pp. 245-260, 2023, DOI:10.32604/biocell.2023.025311

Abstract The association of gut microflora and human health is being increasingly recognized, and the impact of gut microflora on the host is well characterized, including the body’s energy metabolism and immune system maintenance. Several human diseases, including metabolic, autoimmune, obesity, hypothyroidism, and intestinal disorders, are closely associated with gut dysbiosis. Inorganic nanoparticles (NPs) are extensively utilized in numerous fields due to their distinctive, attractive physicochemical properties. Estimation of the potential impacts of NPs, with a high number of microorganisms inside the human body (microbiota) and its genomes (microbiome), represents one of the most important aspects of nano-toxicology. This review article… More > Graphic Abstract

MIAOMIAO LI^1,#, DANYANG CHEN^2,#, JUNYI KE¹, RUILIN ZHENG², JINGYAO SU², ZILIN ZHENG¹, JIEYI LUO¹, HANRAN MAI¹, FAN JIANG¹, YANXIA QU¹, XIAOQIONG GU¹, BING ZHU², YINGHUA LI^2,*, LIANDONG ZUO^1,*

BIOCELL, Vol.47, No.2, pp. 401-408, 2023, DOI:10.32604/biocell.2023.025154

Abstract A H₂O₂-induced oxidative stress injury cell model was established to investigate the antioxidant effect of nano-selenium on mouse spermatocyte lines and the regulation mechanism of the expression level and activity of selenium-containing antioxidant enzymes induced by oxidative stress. A safe and effective nano-drug system of functionalized selenium-containing nanoparticles (SeNPs) was developed with lentinan (LNT) (SeNPs@LNT). Mice spermatocyte line GC2-spg cells were treated with SeNPs@LNT (1, 2, 4, 8, 16, 32 μM) for 24–72 h to evaluate the cytotoxicity of selenium. GC2-spg cells were randomly divided into the following groups: control, hydrogen peroxide (H₂O₂), SeNPs@LNT, and H₂O₂+SeNPs@LNT groups. H₂O₂+SeNPs@LNT group was… More >