TIANZHU LI1,#, YU ZHANG2,#, TONG ZHANG2,#, YANNAN LI2, HUI XUE2, JINGLONG CAO2, WENSHUANG HOU2, YINGHUA LUO3,*, CHENGHAO JIN2,4,*,
BIOCELL, Vol.47, No.1, pp. 195-204, 2023, DOI:10.32604/biocell.2023.025593
- 26 September 2022
Abstract Schisandrin B (Sch B) is a monomer with anti-cancer and anti-inflammatory effects, which are isolated from the
plant Schisandra chinensis (Turcz) Baillon. We investigated the anti-gastric cancer (GC) effects of Sch B and its
underlying molecular mechanisms. The Cell Counting Kit-8 assay was used to determine the effects of Sch B on the
viability of GC and normal cell lines. Hoechst/propidium iodide staining and flow cytometry were used to assess the
apoptosis induction of Sch B. Western blotting was used to evaluate the effects of Sch B on downstream apoptotic
proteins. The DCFH-DA fluorescent probe was… More >
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