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  • Open Access

    ARTICLE

    Analysis of Geometrical Arrangement and Packing Material on Heat Generation in Lithium-Ion Battery Banks

    Seenaa Khudhayer Salman1, Shaymaa Husham Abdulmalek2,*, Ali Ahmed Gitan1, Thamer Khalif Salem3, Raaid Rashad Jassem Al-Doury3

    Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.073940 - 27 January 2026

    Abstract Operating Lithium-ion batteries at their temperature limits is a challenging design task due to explosion risk at high temperatures and rapid degradation at low temperatures. Depending on the battery package design, those risks can be solved with passive solutions, which require no active cooling or heating. The current work aims to optimize the pack design and materials of the type-NCR18650B battery based on a wide range of operation temperature. The lower limit was denoted by cold case while the maximum limit was expressed by hot case. A combined analytical-numerical approach was developed to model the… More >

  • Open Access

    ARTICLE

    A Retrospective Real-World Study: The Efficacy and Safety of Immune Checkpoint Inhibitors Combined with Chemoradiotherapy in Limited-Stage Small Cell Lung Cancer

    Ruoxue Cai1,#, Shuyi Hu2,#, Feiyang Li2, Huanhuan Sha3,*, Guoren Zhou2,*, Ying Fang3

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.070893 - 19 January 2026

    Abstract Objective: To determine whether immunotherapy can bring new hope for patients with limited-stage small-cell lung cancer (LS-SCLC). We conducted this retrospective study to evaluate whether immunotherapy can achieve better efficacy in LS-SCLC patients. Methods: We evaluated 122 LS-SCLC patients who received concurrent chemoradiotherapy (CCRT) or sequential chemoradiotherapy (SCRT) (Group A) and immunotherapy combined with CCRT/SCRT followed by immunotherapy (Group B), to assess the objective response rate (ORR), disease control rate (DCR), and progression-free survival (PFS). Factors affecting prognosis were also explored using Cox analysis. The prognosis of patients with type 2 diabetes and patients with… More >

  • Open Access

    ARTICLE

    A Temperature-Indexed Concrete Damage Plasticity Model Incorporating Bond-Slip Mechanism for Thermo-Mechanical Analysis of Reinforced Concrete Structures

    Wu Feng1,2,*, Tengku Anita Raja Hussin1, Xu Yang3

    Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071664 - 08 January 2026

    Abstract This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700°C by integrating experimental testing and advanced numerical modeling. A temperature-indexed Concrete Damage Plasticity (CDP) framework incorporating bond–slip effects was developed in Abaqus to capture both global stress–strain responses and localized damage evolution. Uniaxial compression tests on thermally exposed cylinders provided residual strength data and failure observations for model calibration and validation. Results demonstrated a distinct two-stage degradation regime: moderate stiffness and strength reduction up to ~400°C, followed by sharp deterioration beyond 500°C–600°C, with residual capacity at… More >

  • Open Access

    ARTICLE

    Evaluation of the Failure Impact of Jet Fire from Natural Gas Leakage on Parallel Pipelines

    Zezhi Wen1, Kai Zhang1, Shanlin Liang2, Liqiong Chen1,*, Zijian Xiong1

    Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.066408 - 08 January 2026

    Abstract Maintaining the structural integrity of parallel natural gas pipelines during leakage-induced jet fires remains a critical engineering challenge. Existing methods often fail to account for the complex interactions among heat transfer, material behavior, and pipeline geometry, which can lead to overly simplified and potentially unsafe assessments. To address these limitations, this study develops a multiphysics approach that integrates small-orifice leakage theory with detailed thermo-fluid-structural simulations. The proposed framework contributes to a more accurate failure analysis through three main components: (1) coupled modeling that tracks transient heat flow and stress development as fire conditions evolve; (2)… More >

  • Open Access

    REVIEW

    The Efficacy and Safety of B-Cell Maturation Antigen (BCMA) Antibody-Drug Conjugates (ADC) in Development against Cancer: A Systematic Review

    Jing Shan1, Catherine King2,3, Harunor Rashid3,4, Veysel Kayser1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070851 - 30 December 2025

    Abstract Objectives: B-cell maturation antigen (BCMA)-targeted antibody–drug conjugates (ADCs) have emerged as promising therapies for relapsed/refractory multiple myeloma (RRMM), but the overall efficacy and safety profile is unclear. This study aimed to synthesize the available evidence on the safety and efficacy of BCMA-ADCs in development for RRMM. Methods: A systematic search was conducted using six bibliographic databases and ClinicalTrials.gov up to November 2024. Studies were eligible if they were human clinical trials or animal studies evaluating BCMA-ADCs and reported efficacy and safety outcomes. Data extraction and quality assessments were conducted using validated tools, including ROBINS-I… More >

  • Open Access

    REVIEW

    Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review

    Giacomo Iovane1,*, Luca Traman2, Michele Maffezzoli1,3, Giuseppe Fornarini2, Domenico Corradi4, Debora Guareschi4, Matteo Santoni5,#, Sebastiano Buti1,#

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070523 - 30 December 2025

    Abstract Background: While the treatment of metastatic renal cell carcinoma (mRCC) is evolving due to immune checkpoint inhibitors (ICIs), optimal strategies for later lines of therapy have yet to be defined. The combination of lenvatinib and everolimus represents a viable option, and the present review aimed to summarize its activity, effectiveness, and safety. Methods: A systematic review of the literature was conducted using PubMed, targeting studies published between 2018 and 2025. Eligible studies included English-language prospective and retrospective trials reporting survival outcomes in mRCC patients treated with lenvatinib and everolimus after at least one ICI-containing regimen. Results:More > Graphic Abstract

    Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review

  • Open Access

    ARTICLE

    Mountain climber outdoor motivation and safety behavior: Does role clarity and safety cognition make a difference to participant safety?

    Gengan Wu1,#, Anqi Jiang1,#, Zihan Chen2, Xinwei Su3,4,*

    Journal of Psychology in Africa, Vol.35, No.6, pp. 853-861, 2025, DOI:10.32604/jpa.2025.073822 - 30 December 2025

    Abstract This study examined the role of role clarity and safety cognition in shaping mountain climbers’ participation motivation and safety behavior. The study sample comprised 454 participants (males = 58.8%, mean age = 32 years, SD = 9.31). They completed measures on five participation motivation dimensions (achievement, interest, knowledge, socialization, and health) and safety participation. The results from structural equation modelling indicated that participant motivations in achievement, health, and knowledge significantly predicted safety participation behavior, such as risk avoidance, self-protection, and mutual assistance, more so than the motivations of interest and socialization. Role clarity moderated the More >

  • Open Access

    ARTICLE

    Customer-employee exchange work through psychological safety and self-efficacy for improved hotel employees’ work engagement

    Fan Deng*

    Journal of Psychology in Africa, Vol.35, No.6, pp. 797-805, 2025, DOI:10.32604/jpa.2025.068735 - 30 December 2025

    Abstract This study investigated the relationship between customer-employee exchange (CEX) and employee work engagement (vigor, dedication, absorption), and the role of psychological safety and self-efficacy mediate that relationship. Survey data were collected from 329 Chinese hotel employees (females = 52.9%, tenure: 1–3 years = 50.5%). The results following ordinary least squares regression and the SPSS PROCESS macro indicate that higher customer-employee exchange is associated with employee vigor, dedication, and absorption. Psychological safety and self-efficacy mediate the relationship between customer-employee exchange and vigor and dedication to be stronger, while the work absorption mediating effect is not significant. More >

  • Open Access

    REVIEW

    Human Behaviour Classification in Emergency Situations Using Machine Learning with Multimodal Data: A Systematic Review (2020–2025)

    Mirza Murad Baig1, Muhammad Rehan Faheem2,*, Lal Khan3,*, Hannan Adeel2, Syed Asim Ali Shah4

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 2895-2935, 2025, DOI:10.32604/cmes.2025.073172 - 23 December 2025

    Abstract With growing urban areas, the climate continues to change as a result of growing populations, and hence, the demand for better emergency response systems has become more important than ever. Human Behaviour Classification (HBC) systems have started to play a vital role by analysing data from different sources to detect signs of emergencies. These systems are being used in many critical areas like healthcare, public safety, and disaster management to improve response time and to prepare ahead of time. But detecting human behaviour in such stressful conditions is not simple; it often comes with noisy… More > Graphic Abstract

    Human Behaviour Classification in Emergency Situations Using Machine Learning with Multimodal Data: A Systematic Review (2020–2025)

  • Open Access

    ARTICLE

    Improving the Performance of AI Agents for Safe Environmental Navigation

    Miah A. Robinson, Abdulghani M. Abdulghani, Mokhles M. Abdulghani, Khalid H. Abed*

    Journal on Artificial Intelligence, Vol.7, pp. 615-632, 2025, DOI:10.32604/jai.2025.073535 - 01 December 2025

    Abstract Ensuring the safety of Artificial Intelligence (AI) is essential for providing dependable services, especially in various sectors such as the military, education, healthcare, and automotive industries. A highly effective method to boost the precision and performance of an AI agent involves multi-configuration training, followed by thorough evaluation in a specific setting to gauge performance outcomes. This research thoroughly investigates the design of three AI agents, each configured with a different number of hidden units. The first agent is equipped with 128 hidden units, the second with 256, and the third with 512, all utilizing the… More >

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