Guo-Qiang Zhou*, Fu Han*, Zhi-Liang Shi*, Liang Yu*, Xue-Feng Li*, Cheng Yu*, Cheng-Long Shen*, Dai-Wei Wan†, Xin-Guo Zhu†, Rui Li‡, Song-Bing He†
Oncology Research, Vol.26, No.5, pp. 795-800, 2018, DOI:10.3727/096504017X15004613574679
Abstract Dysregulation of SUMO-specific protease 1 (SENP1) expression has been reported in several kinds of cancer,
including human colorectal and prostate cancers, proposing SENP1 as an oncogene with a critical role in cancer
progression. miR-133a-3p has been reported as a tumor suppressor in several malignant neoplasias. However,
the precise molecular mechanisms underlying its role in colorectal cancer remain largely unknown. The aim
of this work was to investigate the relationship between miR-133a-3p and SENP1 in colorectal cancer cells.
We found that miR-133a-3p expression was downregulated in colorectal cancer tissues. In silico analyses
indicated that SENP1 is More >
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