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  • Open Access

    ARTICLE

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

    JIAN TANG1, CHENQIANG ZHU1, YUN CHEN1, YUNLONG WU1, MING HE1, YI ZHOU2, MINGHUA XIE2,*

    BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562

    Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest reduction and lasso analysis.… More > Graphic Abstract

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

  • Open Access

    ARTICLE

    Effect of Synthesis Parameters on Phosphoric Acid Doped Polybenzimidazole Membranes: A Parametric Evaluation from Microstructural Level to Fuel Cell Performance

    ÇAĞLA GÜL GÜLDİKEN, LEVENT AKYALÇIN, HASAN FERDİ GERÇEL*

    Journal of Polymer Materials, Vol.36, No.4, pp. 337-349, 2019, DOI:10.32381/JPM.2019.36.04.4

    Abstract In the present study, polybenzimidazole (PBI) polymer which has a great importance in polymer electrolyte membrane (PEM) research was synthesized via the solution polycondensation method, under various synthesis conditions to put forward the effect of the synthesis parameters on the properties of the synthesized polymer and consequently to the quality of the prepared polymer electrolyte membrane. The synthesized polymers were characterized in terms of their chemical structure, thermal degradation behaviour, and molecular weight by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (1 H NMR), thermogravimetric analysis (TGA). The Mechanical properties, acid-doping level capacity, proton conductivity, and fuel cell… More >

  • Open Access

    ARTICLE

    Fabrication of Microspherical Catalyst with Hierarchical Porous Structure from Functional Monomers via Low-Temperature Phase-Separation Photopolymerization

    KEMIN WANG, LIFEI HE

    Journal of Polymer Materials, Vol.36, No.3, pp. 253-260, 2019, DOI:10.32381/JPM.2019.36.03.5

    Abstract This study proposes a simple approach for the fabrication of microspherical catalysts with a hierarchical porous structure. The cross-linked porous microspheres with catalytic ability were prepared directly from small-molecular monomers via low-temperature phase-separation photopolymerization of water/oil suspension. The morphology, pore size, chemical structure, and thermal stability of the obtained porous microspheres were characterized by SEM, Mercury Intrusion Porosimetry, FTIR, and TGA. The porous microspheres directly served as an acid catalyst for the condensation reaction of benzaldehyde and ethylene glycol, which exhibited superior catalytic activity and recyclability. The results indicated that such porous microspheres have great potential in the application of… More >

  • Open Access

    ARTICLE

    Improved Corrosion Resistance of Carbon Reinforced Aluminium Laminates in Atmospheric Environment: Role of Environment Friendly Jute Fibre/ Alumina nano Coating

    M. VASUMATHI1,a,*, VELA MURALI2,b, S. RASHIA BEGUM1,c, N. RAJENDRAN2,d

    Journal of Polymer Materials, Vol.36, No.1, pp. 1-11, 2019, DOI:10.32381/JPM.2019.36.01.1

    Abstract In the Fibre Metal Laminate (FML), Carbon Reinforced Aluminium laminate (CARALL), aluminium is placed next to carbon fibres. The potential difference between the aluminium and carbon is larger, leads to galvanic corrosion, which tries to bring down the durability of the FML. To bring down the effect of corrosion, a material layer is introduced between fibres and aluminium so as to separate them thus lowering the possibility of occurrence of corrosion. Another approach is to coat the surfaces of aluminium with different proportions of aluminium oxide nano particles prior to fabrication of the FML. For both the cases, corrosion rates… More >

  • Open Access

    ARTICLE

    Glass/Biofibers/Epoxy Methacrylate of Bisphenol-C Sandwich Composites: Comparative Mechanical and Electrical Properties and Chemical Resistance

    RITESH D. BHATT, JIGNESH P. PATEL, P. H. PARSANIA*

    Journal of Polymer Materials, Vol.38, No.1-2, pp. 71-87, 2021, DOI:10.32381/JPM.2021.38.1-2.7

    Abstract Glass/Biofibers/Epoxy methacrylate of bisphenol-C (G/BF/EBCMAS) sandwich composites was prepared by compression molding. G/BF/EBCMAS showed good mechanical and good to excellent electrical properties and excellent chemical resistance. Studied properties are compared with EBCMAS and G/EBCMAS. In comparison with G/EBCMAS, G/BF/EBCMAS showed considerable decline of tensile strength (18-63.4%), flexural strength (18.8-38.7%), flexural modulus (12.8-50.7%), Izod impact strength (17.4-43.5%), Barcol hardness (2.1-16.7%) and dielectric strength (23.8-76.8%) except flexural strength of G/BM/EBCMAS. G/WC/EBCMAS (96.7%), G/B/EBCMAS (79.2%), G/GN/EBCMAS (83.3%) and G/RH/EBCMAS (97.9%) showed decline of volume resistivity, whereas other sandwich composites showed 1150-58233% improvement. The decrease in mechanical properties and dielectric strength of G/BF/EBCMAS sandwich… More >

  • Open Access

    ARTICLE

    Preparation of Chitin-Glucan Microsphere via SprayDrying Technique and their Antibacterial Activity

    ANU SINGH AND P.K. DUTTA*

    Journal of Polymer Materials, Vol.38, No.1-2, pp. 63-69, 2021, DOI:10.32381/JPM.2021.38.1-2.6

    Abstract The experiment was designed to examine the microsphere of the chitin-glucan complex. We formed a chitin-glucan microsphere (ChGMS) from the spray dryer technique. SEM images observed that shape of ChGMS was spherical. From particle size analyzer and SEM analysis both showed that the size of particles was in the range of 1.5 to 3.5 µm. It showed amorphous nature after the formation of microsphere particles of chitin-glucan. The effect of chitin-glucan complex and ciprofloxacin loaded chitin-glucan microsphere on Bacillus subtilis and Escherichia coli were also tested. Antibacterial analysis was indicating that the ciprofloxacin loaded chitinglucan microsphere strongly inhibited the growth… More >

  • Open Access

    ARTICLE

    A study on Flame-retardancy Property of UV Curable Epoxy Coating for Wooden Surfaces using Boron Diluent and Phosphorus Based Initiator

    RAJKUMAR SINGH RAWAT1,2, MEENU TALWAR1,*, RAJENDRA KUMAR DIWAN2, AJAY KUMAR TYAGI1

    Journal of Polymer Materials, Vol.38, No.3-4, pp. 281-294, 2021, DOI:10.32381/JPM.2021.38.3-4.9

    Abstract In the present paper,boron based diluent was synthesized and incorporated in to a Ultraviolet (UV) radiation curable epoxy coating composition comprising of phosphorus based initiator (Trimethylbenzoyl diphenyl phosphine oxide) for enhancing its flame retardant property. The boron based diluent was synthesized by thermal polymerization technique. The presence of boron and phosphorus on the coating surface was confirmed by Energy Dispersive X-Ray (EDX) and X-ray photoelectron spectroscopy (XPS) techniques and functionality was determination by Fourier Transform Infra-Red (FTIR) and proton/boron NMR spectroscopy technique. The flame retardency property of the coating composition was confirmed by determining limiting oxygen index,vertical burning test, rate… More >

  • Open Access

    ARTICLE

    Fabrication and Comparative Properties of Sustainable Epoxy Methacrylate of Bisphenol-C-Jute/Treated JuteNatural Fibers Sandwich Composites: Part-2

    RITESH D. BHATT, JIGNESH P. PATEL, PARSOTAM H. PARSANIA*

    Journal of Polymer Materials, Vol.39, No.3-4, pp. 223-239, 2022, DOI:10.32381/JPM.2022.39.3-4.4

    Abstract Compression-molded epoxy methacrylate of bisphenol-C-jute/treated jute-banana/groundnut/ cane sugar/pineapple leaf/rice husk/wheat husk sandwich composites were fabricated under 5 MPa pressure at room temperature for 3 h. Alkali treated jute-natural fiber sandwich composites displayed considerably improved mechanical properties over untreated jute-natural fiber sandwich composites due to surface modification of the jute fibers. Both types of sandwich composites showed high water uptake tendency, excellent hydrolytic stability against acids, alkali, and salt solutions, and also a longer equilibrium time at 30o C. Alkali treated sandwich composites revealed a considerably lower water uptake tendency than untreated sandwich composites. Observed water uptake trend is H2 SO4More >

  • Open Access

    ARTICLE

    Fabrication and Comparative Properties of Sustainable Epoxy Methacrylate of Bisphenol-C-Jute/Treated JuteNatural Fibers Sandwich Composites: Part-1

    RITESH D. BHATT, JIGNESH P. PATEL, PARSOTAM H. PARSANIA*

    Journal of Polymer Materials, Vol.39, No.3-4, pp. 205-221, 2022, DOI:10.32381/JPM.2022.39.3-4.3

    Abstract Epoxy methacrylate of bisphenol-C-jute/treated jute and their sandwich composites of white coir, brown coir, wild almond, bamboo, betel nut, and palmyra were prepared by a compression molding technique under 5MPa pressure and at room temperature for three h. The neat sample showed almost double tensile strength than its jute composite, while it is comparable for treated jute. The composites revealed substantially improved flexural strength compared to neat. The neat, jute/treated jute and their sandwich composites indicated good impact strength, pretty good Barcol hardness, and fairly good electric strength. The neat sample showed excellent volume resistivity, while jute/treated jute and their… More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of Bisphenol-C Epoxy Crotonate and Its Fiber-Reinforced Composites

    PARSOTAM H. PARSANIA1,*, JIGNESH V. PATEL2, JIGNESH P. PATEL3

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 271-284, 2023, DOI:10.32381/JPM.2023.40.3-4.9

    Abstract Bisphenol-C epoxy crotonate resin was synthesized by reacting 8.09g epoxy resin of bisphenolC, and 2.15g crotonic acid using 25 mL 1,4-dioxane as a solvent, and 1 mL triethylamine as a catalyst at reflux temperature for 1-6 h. Solid epoxy crotonate (ECCR) is highly soluble in common organic solvents. ECCR was characterized by its acid (24.5-1.5 mg KOH/g) and hydroxyl (504.5-678.4 mg KOH/g) values. The structure of ECCR is supported by FTIR and 1 HNMR spectroscopic methods. A DSC endothermic transition at 229o C indicated melting followed by thermal polymerization of ECCR. ECCR is thermally stable up to 320o C and… More >

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