Xiaorui Liu*†1, Jingjing Li*1, Zujiang Yu*, Juan Li*, Ranran Sun*, Quancheng Kan‡
Oncology Research, Vol.25, No.3, pp. 427-435, 2017, DOI:10.3727/096504016X14747300207374
Abstract Hepatocellular carcinoma (HCC) is the most common cancer in the world. MicroRNAs (miRNAs) are a type
of small noncoding RNA that can regulate the expression of target genes under physiological and pathophysiological conditions. Aberrant expression of microRNA-935 (miR-935) has been reported in cancer studies.
However, its expression and mechanism in HCC remain unclear. In our study, we found that miR-935 was
upregulated in liver cancer tissues and cells. Overexpression of miR-935 in liver cells promoted cell proliferation, tumorigenesis, and cell cycle progression, whereas inhibition of miR-935 reduced cell proliferation,
tumorigenicity, and cell cycle progression. These… More >
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