WEILAN LIU, XIAOYAN DUAN, KAIYUN QIN, YAN JIANG, CAIFU ZHAO, CONGWEI DAI^*

BIOCELL, Vol.47, No.11, pp. 2471-2484, 2023, DOI:10.32604/biocell.2023.029617 - 27 November 2023

Abstract Introduction: Structural maintenance of chromosome 1A (SMC1A) is a crucial compound of the cohesin complex. It has been reported to regulate the epithelial-mesenchymal transition (EMT) process in multiple cancers. Objectives: The present study aims to further clarify the role of SMC1A in cervical cancer. Methods: We analyzed data from four datasets and confirmed that SMC1A showed high expression in cervical cancer samples and was related to poor prognosis of patients with cervical cancer. Cell proliferation of SiHa and C-33A with knockdown of SMC1A was assessed using CCK-8 and colony formation assay. The migration and invasion were… More > Graphic Abstract

Xiangfei Li, Yang Yin, Yang Zhou, Wenchang Liu, Kaihui Zhao^*

Energy Engineering, Vol.120, No.2, pp. 277-297, 2023, DOI:10.32604/ee.2023.022461 - 29 November 2022

Abstract This paper presents a novel non-singular fast terminal sliding mode control (NFTSMC) based on the deep flux weakening switching point tracking method in order to improve the control performance of permanent interior magnet synchronous motor (IPMSM) drive systems. The mathematical model of flux weakening (FW) control is established, and the deep flux weakening switching point is calculated accurately by analyzing the relationship between the torque curve and voltage decline curve. Next, a second-order NFTSMC is designed for the speed loop controller to ensure that the system converges to the equilibrium state in finite time. Then, More > Graphic Abstract

Ahmed M. Elmogy^1,2,*, Wael M. Elawady²

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 385-400, 2023, DOI:10.32604/iasc.2023.032349 - 29 September 2022

Abstract One of the great concerns when tackling nonlinear systems is how to design a robust controller that is able to deal with uncertainty. Many researchers have been working on developing such type of controllers. One of the most efficient techniques employed to develop such controllers is sliding mode control (SMC). However, the low order SMC suffers from chattering problem which harm the actuators of the control system and thus unsuitable to be used in many practical applications. In this paper, the drawbacks of low order traditional sliding mode control (FOTSMC) are resolved by presenting a… More >

A. Jegatheesh^1,*, M. Germin Nisha², N. Kopperundevi³

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 745-760, 2023, DOI:10.32604/iasc.2023.028011 - 29 September 2022

Abstract Interacting The highest storage capacity of a circular tank makes it popular in process industries. Because of the varying surface area of the cross-sections of the tank, this two-tank level system has nonlinear characteristics. Controlling the flow rate of liquid is one of the most difficult challenges in the production process. This proposed effort is critical in preventing time delays and errors by managing the fluid level. Several scholars have explored and explored ways to reduce the problem of nonlinearity, but their techniques have not yielded better results. Different types of controllers with various techniques… More >

Ahmed M. Elmogy^1,2,*, Amany Sarhan², Wael M. Elawady²

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5629-5641, 2022, DOI:10.32604/cmc.2022.025247 - 21 April 2022

Abstract As most real world systems are significantly nonlinear in nature, developing robust controllers have attracted many researchers for decades. Robust controllers are the controllers that are able to cope with the inherent uncertainties of the nonlinear systems. Many control methods have been developed for this purpose. Sliding mode control (SMC) is one of the most commonly used methods in developing robust controllers. This paper presents a higher order SMC (HOSMC) approach to mitigate the chattering problem of the traditional SMC techniques. The developed approach combines a third order SMC with an adaptive PID (proportional, integral, More >

Kaihui Zhao^1,2, Wenchang Liu¹, Tonghuan Yin³, Ruirui Zhou⁴, Wangke Dai¹ and Gang Huang^5,*

Energy Engineering, Vol.119, No.2, pp. 767-780, 2022, DOI:10.32604/EE.2021.018617 - 24 January 2022

Abstract This paper presents a novel model-free sliding mode control (MFSMC) method to improve the speed response of permanent magnet synchronous machine (PMSM) drive system. The ultra-local model (ULM) is first derived based on the input and the output of the PMSM. Then, the novel MFSMC method is presented, and the controller is designed based on ULM and MFSMC. A sliding mode observer (SMO) is constructed to estimate the unknown part of the ULM. The estimated unknown part is feedbacked to MFSMC controller to perform compensation for parameter perturbations and external disturbances. Compared with the sliding More >

TING LAN, SHENG QIN, XIAOJIN GONG, PING ZHENG, JIAXIN YAN, YANG LIU^*

BIOCELL, Vol.45, No.5, pp. 1313-1319, 2021, DOI:10.32604/biocell.2021.015923 - 12 July 2021

Abstract Invasive stratified mucin-producing carcinoma (ISMC) is a recently described histologic variant of high-risk human papillomavirus (HPV)-associated endocervical adenocarcinoma, as the putative invasive counterpart of the stratified mucin-producing intraepithelial lesion (SMILE). ISMC can display variable architectural patterns and usually coexists with other more conventional types of HPV-associated carcinomas, which makes diagnosis and differential diagnosis of ISMC is difficult for pathologists. Moreover, the prognosis of ISMC is still controversial. We analyzed 6 ISMCs with detailed pathological and clinical information. Intraepithelial lesion, including 1 high-grade squamous intraepithelial lesion and 1 SMILE, was found. Various architectures were observed (including… More >

Yi Liang^1,*, Shaokang Zeng¹, Xiaoxian Xu², Shilu Chang¹, Xing Su¹

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1697-1717, 2021, DOI:10.32604/cmc.2020.012513 - 26 November 2020

Abstract Spark is the most popular in-memory processing framework for big data analytics. Memory is the crucial resource for workloads to achieve performance acceleration on Spark. The extant memory capacity configuration approach in Spark is to statically configure the memory capacity for workloads based on user’s specifications. However, without the deep knowledge of the workload’s system-level characteristics, users in practice often conservatively overestimate the memory utilizations of their workloads and require resource manager to grant more memory share than that they actually need, which leads to the severe waste of memory resources. To address the above… More >

Nikhil Gadewal^*1, Rohit Kumar^†1, Swapnil Aher^†, Anagha Gardane^†, Tarang Gaur^†, Ashok K. Varma^*‡§, Navin Khattry^¶, Syed K. Hasan^†§¶

Oncology Research, Vol.28, No.3, pp. 321-330, 2020, DOI:10.3727/096504020X15816752427321

Abstract Acute myeloid leukemia (AML) with NPM1 mutation is a disease driving genetic alteration with good prognosis. Although it has been suggested that NPM1 mutation induces chemosensitivity in leukemic cells, the underlying cause for the better survival of NPM1 mutated patients is still not clear. Mutant NPM1 AML has a unique microRNA and their target gene (mRNA) signature compared to wild-type NPM1. Dynamic regulation of miRNA–mRNA has been reported to influence the prognostic outcome. In the present study, in silico expression data of miRNA and mRNA in AML patients was retrieved from genome data commons, and differentially expressed miRNA… More >

Qian Xiao¹, Xia Tang¹, Yuanxiu Chen¹, Han Bao¹, Lizhi Gao^1,2, Xiaobo Gong^3,*, Ping Zhang^1,4,*

Molecular & Cellular Biomechanics, Vol.16, No.3, pp. 199-210, 2019, DOI:10.32604/mcb.2019.07107

Abstract Adrenocorticotrophic hormone (ACTH), a 39-amino acid peptide hormone, has been reported in the appreciation of the proliferation of vascular smooth muscle cells (VSMCs), however, the mechanism in molecular scale supporting the appreciation remains to be elucidated. In this study, we observed that the protein expression levels of ACTH at 24 h after exposure to 15% cyclic stretch were significantly higher than that after 5% cyclic stretch. When VSMCs were treated with 1000 nM ACTH directly, Oct-1 and lamin B1 expression were both up-regulated associating with each other, and the presence of Oct-1 was found shuttling… More >