L. Amaadour, I. Lahrch, O. Siyouri, K. Oualla, Z. Benbrahim, S. Arifi, C. Aarab, S. El Fakir, N. Mellas

Psycho-Oncologie, Vol.17, No.1, pp. 38-43, 2023, DOI:10.3166/pson-2022-0221

Abstract Background: The Covid-19 disease is a cause for several mental alterations mainly in cancer patients who are already categorized as a vulnerable population.
Aim: The objective of this study is to characterize psychological disorders caused by Covid-19 infection among cancer patients on systemic treatment.
Methods: It is a cross-sectional study performed at the Department of Medical Oncology of Hassan-II University Hospital of Fez, Morocco, during a period of four months (peak of the pandemic). Symptoms of anxiety/depression and post-traumatic stress disorder in patients were screened using HADS (Hospital Anxiety and Depression Scale) and PCL-5 (post-traumatic stress disorder checklist version DSM-5)… More >

Hassam Tahir¹, Muhammad Shahbaz Khan¹, Fawad Ahmed², Abdullah M. Albarrak³, Sultan Noman Qasem³, Jawad Ahmad^4,*

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3517-3535, 2023, DOI:10.32604/cmc.2023.035410

Abstract The COVID-19 outbreak began in December 2019 and was declared a global health emergency by the World Health Organization. The four most dominating variants are Beta, Gamma, Delta, and Omicron. After the administration of vaccine doses, an eminent decline in new cases has been observed. The COVID-19 vaccine induces neutralizing antibodies and T-cells in our bodies. However, strong variants like Delta and Omicron tend to escape these neutralizing antibodies elicited by COVID-19 vaccination. Therefore, it is indispensable to study, analyze and most importantly, predict the response of SARS-CoV-2-derived t-cell epitopes against Covid variants in vaccinated and unvaccinated persons. In this… More >

Shangwe Charmant Nicolas^*

Journal of Intelligent Medicine and Healthcare, Vol.1, No.2, pp. 55-68, 2022, DOI:10.32604/jimh.2022.033058

Abstract The COVID-19 outbreak has taken a toll on humankind and the world’s health to a breaking point, causing millions of deaths and cases worldwide. Several preventive measures were put in place to counter the escalation of COVID-19. Usage of face masks has proved effective in mitigating various airborne diseases, hence immensely advocated by the WHO (World Health Organization). A compound CNN-LSTM network is developed and employed for the recognition of masked and none masked personnel in this paper. 3833 RGB images, including 1915 masked and 1918 unmasked images sampled from the Real-World Masked Face Dataset (RMFD) and the Simulated Masked… More >

WEI WANG^1,#, YANRONG PEI^2,#, SHUI-HUA WANG¹, JUAN MANUEL GORRZ³, YU-DONG ZHANG^1,*

BIOCELL, Vol.47, No.2, pp. 373-384, 2023, DOI:10.32604/biocell.2023.025905

Abstract Since 2019, the coronavirus disease-19 (COVID-19) has been spreading rapidly worldwide, posing an unignorable threat to the global economy and human health. It is a disease caused by severe acute respiratory syndrome coronavirus 2, a single-stranded RNA virus of the genus Betacoronavirus. This virus is highly infectious and relies on its angiotensin-converting enzyme 2-receptor to enter cells. With the increase in the number of confirmed COVID-19 diagnoses, the difficulty of diagnosis due to the lack of global healthcare resources becomes increasingly apparent. Deep learning-based computer-aided diagnosis models with high generalisability can effectively alleviate this pressure. Hyperparameter tuning is essential in… More >

QIANG WANG^#, GUO ZHAO^#, LONGXIANG XIE^#, XUAN LI, XIXI YU, QIONGSHAN LI, BAOPING ZHENG, ZULIPINUER WUSIMAN, XIANGQIAN GUO^*

BIOCELL, Vol.47, No.2, pp. 367-371, 2023, DOI:10.32604/biocell.2023.025310

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen of the ongoing coronavirus disease 2019 (COVID-19) global pandemic. Here, by centralizing published cell-based experiments, clinical trials, and virtual drug screening data from the NCBI PubMed database, we developed a database of SARS-CoV-2 inhibitors for COVID-19, dbSCI, which includes 234 SARS-CoV-2 inhibitors collected from publications based on cell-based experiments, 81 drugs of COVID-19 in clinical trials and 1305 potential SARS-CoV-2 inhibitors from bioinformatics analyses. dbSCI provides four major functions: (1) search the drug target or its inhibitor for SARS-CoV-2, (2) browse target/inhibitor information collected from cell experiments, clinical trials, and… More >

Tahir Khan¹, Rahman Ullah¹, Thabet Abdeljawad^2,3,*, Manar A. Alqudah⁴, Faizullah Faiz⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.2, pp. 1295-1313, 2023, DOI:10.32604/cmes.2022.022177

Abstract We propose a theoretical study investigating the spread of the novel coronavirus (COVID-19) reported in Wuhan City of China in 2019. We develop a mathematical model based on the novel corona virus's characteristics and then use fractional calculus to fractionalize it. Various fractional order epidemic models have been formulated and analyzed using a number of iterative and numerical approaches while the complications arise due to singular kernel. We use the well-known Caputo-Fabrizio operator for the purposes of fictionalization because this operator is based on the non-singular kernel. Moreover, to analyze the existence and uniqueness, we will use the well-known fixed… More >

LARISSA DANIELE BOBERMIN^1,*, LARA SCOPEL MEDEIROS², FERNANDA WEBER², GIANCARLO TOMAZZONI DE OLIVEIRA², LUCÉLIA SANTI^3,4,5, WALTER ORLANDO BEYS-DA-SILVA^3,4,5, CARLOS-ALBERTO GONÇALVES^1,2,6, ANDRÉ QUINCOZES-SANTOS^1,2,6

BIOCELL, Vol.46, No.12, pp. 2517-2523, 2022, DOI:10.32604/biocell.2022.021566

Abstract Glial cells are crucial for maintaining central nervous system (CNS) homeostasis. They actively participate in immune responses, as well as form functional barriers, such as blood-brain barrier (BBB), which restrict the entry of pathogens and inflammatory mediators into the CNS. In general, viral infections during the gestational period can alter the embryonic and fetal environment, and the related inflammatory response may affect neurodevelopment and lead to behavioral dysfunction during later stage of life, as highlighted by our group for Zika virus infection. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces a cytokine storm and, during pregnancy, may be related to a… More >

LORIS RIZZELLO^1,2,3, VALERIA DE MATTEIS^4,*

BIOCELL, Vol.46, No.11, pp. 2369-2380, 2022, DOI:10.32604/biocell.2022.021059

Abstract The SARS-CoV-2 outbreaks highlighted the need for effective, reliable, fast, easy-to-do and cheap diagnostics procedures. We pragmatically experienced that an early positive-case detection, inevitably coupled with a mass vaccination campaign, is a milestone to control the COVID-19 pandemic. Gold nanoparticles (AuNPs) can indeed play a crucial role in this context, as their physicochemical, optics and electronics properties are being extensively used in photothermal therapy (PTT), radiation therapy (RT), drug delivery and diagnostic. AuNPs can be synthesized by several approaches to obtain different sizes and shapes that can be easily functionalized with many kinds of molecules such as antibodies, proteins, probes,… More >

Fawaz Alsolami¹, Abdullah Saad Al-Malaise Alghamdi², Asif Irshad Khan^1,*, Yoosef B. Abushark¹, Abdulmohsen Almalawi¹, Farrukh Saleem², Alka Agrawal³, Rajeev Kumar⁴, Raees Ahmad Khan³

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 2591-2618, 2022, DOI:10.32604/cmc.2022.025703

Abstract The COVID-19 pandemic has triggered a global humanitarian disaster that has never been seen before. Medical experts, on the other hand, are undecided on the most valuable treatments of therapy because people ill with this infection exhibit a wide range of illness indications at different phases of infection. Further, this project aims to undertake an experimental investigation to determine which treatments for COVID-19 disease is the most effective and preferable. The research analysis is based on vast data gathered from professionals and research journals, making this study a comprehensive reference. To solve this challenging task, the researchers used the HF… More >

Hirdayesh Anuragi¹, Rajesh Kumar Singhal², Yashfa Tanveer³, Humaira Yasmin³, Ambati Srijan⁴, Alka Bharati¹, Lal Chand⁵, Sukumar Taria¹, Kunasekaran Rajarajan¹, Asha Ram¹, Arun Kumar Handa¹, Ayyanadar Arunachalam¹, Khalid Rehman Hakeem^6,7,8,*, Deniz Özbilici⁹, Ayman EL Sabagh^10,11,*

Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1831-1858, 2022, DOI:10.32604/phyton.2022.020540

Abstract A severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led novel coronavirus disease (COVID-19) outbreak spread through China has become the biggest global public health challenge today. The virus upon several mutations has led to the resurgence of more infectious and lethal variants infecting over 298 million people with more than 5.46 million deaths worldwide by the end of December, 2021. Though vaccines are available, various preventive measures particularly a high body immunity is still extremely important which determines the likelihood of disease severity and subsequent recovery in the current and future pandemics. This review acknowledges the potentiality of miraculous Moringa oleifera… More >