SOROUSH SOLEYMANI1, MOHAMMAD DOROUDIAN2,*, MAHDIEH SOEZI3,4, ALI BELADI5, KIARASH ASGARI2, ASO MOBARAKSHAHI2, ARYANA AGHAEIPOUR2, RONAN MACLOUGHLIN6,7,8,*
Oncology Research, Vol.33, No.1, pp. 15-26, 2025, DOI:10.32604/or.2024.053069
- 20 December 2024
Abstract Brain metastasis and primary glioblastoma multiforme represent the most common and lethal malignant brain tumors. Its median survival time is typically less than a year after diagnosis. One of the major challenges in treating these cancers is the efficiency of the transport of drugs to the central nervous system. The blood-brain barrier is cooperating with advanced stages of malignancy. The blood-brain barrier poses a significant challenge to delivering systemic medications to brain tumors. Nanodrug delivery systems have emerged as promising tools for effectively crossing this barrier. Additionally, the development of smart nanoparticles brings new hope More >
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