Binyang Zhao¹, Fengchan Wu², Guojun Cai³, Peiyu Xi², Yulin Guo², Anding Li^2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1345-1363, 2024, DOI:10.32604/phyton.2024.050950

Abstract In order to explore the response mechanism of Passiflora edulis Sims to drought stress, the changes in morphological and physiological traits of Passiflora edulis Sims under different drought conditions were studied. A total of 7 germplasm resources of Passiflora edulis Sims were selected and tested under drought stress by the pot culture method under 4 treatment levels: 75%–80% (Control, CK) of maximum field water capacity, 55%–60% (Light Drought, LD) of maximum field water capacity, i.e., mild drought, 40%–45% (Moderate Drought, MD) of maximum field water capacity, i.e., moderate drought and 30%–35% (Severe Drought, SD) of maximum field water… More >

Khalid A. Al-Gaadi^1,2, Ahmed M. Zeyada¹, ElKamil Tola^2,*, Abdullah M. Alhamdan^1,3, Khalid A.M. Ahmed^3,4, Rangaswamy Madugundu², Mohamed K. Edrris²

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1311-1323, 2024, DOI:10.32604/phyton.2024.049535

Abstract From economic and nutritional points of view, tomato is, historically, considered one of the most important crops. Without significant yield reduction, most commercial cultivars of tomato crops are sensitive to moderate levels of salinity. However, high levels of salt stress can negatively affect the yield and quality of tomato fruits. Therefore, this study was conducted to evaluate the yield and fruit quality of three tomato cultivars (Forester, Ghandowra-F1, and Feisty-Red) cultivated hydroponically, under three different levels of nutrient solution salinity. Evaluation of tomato fruits was performed based on quantity (number and weight of fruits, and… More >

Song Deng^1,*, Yiming Yuan²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 3679-3697, 2024, DOI:10.32604/cmc.2024.052008

Abstract Malicious attacks against data are unavoidable in the interconnected, open and shared Energy Internet (EI), Intrusion tolerant techniques are critical to the data security of EI. Existing intrusion tolerant techniques suffered from problems such as low adaptability, policy lag, and difficulty in determining the degree of tolerance. To address these issues, we propose a novel adaptive intrusion tolerance model based on game theory that enjoys two-fold ideas: 1) it constructs an improved replica of the intrusion tolerance model of the dynamic equation evolution game to induce incentive weights; and 2) it combines a tournament competition More >

Jie Ma¹, Pengcheng Yue², Haozheng Yu¹, Yuqing Zhang³, Youwen Zhang¹, Cuiping Li³, Junhui Li^3,*, Wenwen Qin³, Yong Guo¹

Energy Engineering, Vol.121, No.7, pp. 1823-1846, 2024, DOI:10.32604/ee.2024.048225

Abstract In recent years, the proportion of installed wind power in the three north regions where wind power bases are concentrated is increasing, but the peak regulation capacity of the power grid in the three north regions of China is limited, resulting in insufficient local wind power consumption capacity. Therefore, this paper proposes a two-layer optimal scheduling strategy based on wind power consumption benefits to improve the power grid's wind power consumption capacity. The objective of the upper model is to minimize the peak-valley difference of the system load, which is mainly to optimize the system… More >

Fangjin Lu^*†, Ying Zheng^‡, Paul Owusu Donkor^*, Peng Zou^§, Ping Mu^†

Oncology Research, Vol.24, No.3, pp. 171-179, 2016, DOI:10.3727/096504016X14634208142987

Abstract The cyclic-AMP response element-binding protein (CREB), a well-known nuclear transcription factor, has been shown to play an essential role in many cellular processes, including differentiation, cell survival, and cell proliferation, by regulating the expression of downstream genes. Recently, increased expression of CREB was frequently found in various tumors, indicating that CREB is implicated in the process of tumorigenesis. However, the effects of CREB on Hodgkin lymphoma (HL) remain unknown. To clarify the role of CREB in HL, we performed knockdown experiments in HL. We found that downregulation of CREB by short hairpin RNA (shRNA) resulted… More >

Enrico Mini^*, Ida Landini^*, Laura Lucarini^†, Andrea Lapucci^*, Cristina Napoli^‡, Gabriele Perrone^*, Renato Tassi^*, Emanuela Masini^†, Flavio Moroni^†, Stefania Nobili^‡

Oncology Research, Vol.25, No.9, pp. 1441-1451, 2017, DOI:10.3727/096504017X14926854178616

Abstract The poly(ADP-ribose) polymerase (PARP) enzymes play a key role in the regulation of cellular processes (e.g., DNA damage repair, genomic stability). It has been shown that PARP inhibitors (PARPIs) are selectively cytotoxic against cells having dysfunctions in genes involved in DNA repair mechanisms (synthetic lethality). Drug-induced PARP inhibition potentiates the activity of anticancer drugs such as 5-fluorouracil in enhancing DNA damage, whose repair involves PARP-1 activity. The aim of this study was to evaluate the inhibitory effects of a novel PARPI, HYDAMTIQ, on growth in human tumor cell lines characterized by different features with regard… More >

Xiaoyu Wu^*1, Jin Zhou^†1, Zhenfeng Wu^*, Che Chen^*, Jiayun Liu^*, Guannan Wu^*, Jing Zhai^*, Fukun Liu^*, Gang Li^‡

Oncology Research, Vol.25, No.8, pp. 1383-1390, 2017, DOI:10.3727/096504017X14879366402279

Abstract miR-101-3p has been identified as a tumor suppressor in several cancers, but its exact role in gastric adenocarcinoma is still largely unknown. In this study, we found that, compared with the RGM-1 human normal gastric epithelial cells, miR-101-3p was significantly downregulated in all six human gastric adenocarcinoma cell lines, including BGC-823, MNK-45, MGC-803, SGC-7901, AGS, and HGC-27. Overexpression of miR- 101-3p suppressed both the proliferation and invasion of AGS gastric adenocarcinoma cells, and knockdown of miR-101-3p displayed the opposite effect. In addition, miR-101-3p could directly target and suppress the expression of the serum response factor More >

Fen Liu^*†, Shaojun Liu^*, Feiyan Ai^*†, Decai Zhang^*†, Zhiming Xiao^*, Xinmin Nie^‡, Yunfeng Fu^§

Oncology Research, Vol.25, No.6, pp. 967-974, 2017, DOI:10.3727/096504016X14803476672380

Abstract Colorectal cancer (CRC) is one of the most common malignancies in the world, with a high incidence and a high mortality. However, the pathogenesis of CRC carcinogenesis is still unexplored. In this study, we investigated the role of miR-107 in the regulation of CRC cell proliferation and apoptosis. First, the expression of miR-107 was observed to be aberrantly increased in human CRC tumor tissues and cell lines when compared to the colonic control tissues and colon epithelial cells. Further study showed that the proliferative and apoptotic capacities of human CRC SW480 and LoVo cells were… More >

Jing Zheng, Jianya Zhou, Yanping Zhu, Qian Shen, Jianying Zhou

Oncology Research, Vol.25, No.4, pp. 545-550, 2017, DOI:10.3727/096504016X14801968368898

Abstract Pancreatic metastasis from non-small cell lung cancer (NSCLC) is usually asymptomatic or presents with abdominal pain, acute pancreatitis, or jaundice. A lung primary is associated with worse survival compared to pancreatic metastases from other organs. Surgical treatment of solitary metastasis to the pancreas from NSCLC has been reviewed in several studies, one of which had a notable disease-free interval. To our knowledge, there are no prior reports of targeted therapy of pancreatic metastasis of NSCLC followed by a significant response. Herein we report the case of a 31-year-old female with a solitary pancreatic metastasis from ALK-rearranged More >

Enrico Mini^*, Ida Landini^*, Laura Lucarini^†, Andrea Lapucci^*, Cristina Napoli^‡, Gabriele Perrone^*, Renato Tassi^*, Emanuela Masini^†, Flavio Moroni^†, Stefania Nobili^‡

Oncology Research, Vol.26, No.2, pp. 333-334, 2018, DOI:10.3727/096504018X15187172557369

Abstract The poly(ADP-ribose) polymerase (PARP) enzymes play a key role in the regulation of cellular processes (e.g., DNA damage repair, genomic stability). It has been shown that PARP inhibitors (PARPIs) are selectively cytotoxic against cells having dysfunctions in genes involved in DNA repair mechanisms (synthetic lethality). Drug-induced PARP inhibition potentiates the activity of anticancer drugs such as 5-fluorouracil in enhancing DNA damage, whose repair involves PARP-1 activity. The aim of this study was to evaluate the inhibitory effects of a novel PARPI, HYDAMTIQ, on growth in human tumor cell lines characterized by different features with regard… More >