Jie Zhang, Jiaxiang Zhao*, Pengchang Xu
CMES-Computer Modeling in Engineering & Sciences, Vol.131, No.2, pp. 905-917, 2022, DOI:10.32604/cmes.2022.019097
- 14 March 2022
Abstract Accurately, reliably and rapidly identifying intrinsically disordered (IDPs) proteins is essential as they often play important roles in various human diseases; moreover, they are related to numerous important biological activities. However, current computational methods have yet to develop a network that is sufficiently deep to make predictions about IDPs and demonstrate an improvement in performance. During this study, we constructed a deep neural network that consisted of five identical variant models, ResNet18, combined with an MLP network, for classification. Resnet18 was applied for the first time as a deep model for predicting IDPs, which allowed More >