Ying Liu*†, Hui Lv‡, Xiaoying Wu*§, Jun Zhou¶, Ying Shi#, Jifang Wen*†
Oncology Research, Vol.25, No.3, pp. 445-454, 2017, DOI:10.3727/096504016X14747368729786
Abstract Breast cancer is the leading cause of cancer deaths in females all over the world, mainly resulting from metastasis. Previous studies have revealed that repressor element-1 (RE-1) silencing transcription (REST) acted as
a tumor suppressor in breast cancer. However, the mechanism by which REST is regulated remains unknown,
and its role in the metastasis in breast cancer cells remains unclear. In the present study, we showed that the
expression of REST was lower in breast cancer samples than that of adjacent samples by immunohistochemical analysis, which may be due to hypermethylation of the REST promoter.… More >
Login
Register
