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    ARTICLE

    A developed ant colony algorithm for cancer molecular subtype classification to reveal the predictive biomarker in the renal cell carcinoma

    ZEKUN XIN1,#, YUDAN MA2,#, WEIQIANG SONG3, HAO GAO3, LIJUN DONG3, BAO ZHANG1,*, ZHILONG REN3,*

    BIOCELL, Vol.47, No.3, pp. 555-567, 2023, DOI:10.32604/biocell.2023.026254 - 03 January 2023

    Abstract Background: Recently, researchers have been attracted in identifying the crucial genes related to cancer, which plays important role in cancer diagnosis and treatment. However, in performing the cancer molecular subtype classification task from cancer gene expression data, it is challenging to obtain those significant genes due to the high dimensionality and high noise of data. Moreover, the existing methods always suffer from some issues such as premature convergence. Methods: To address those problems, we propose a new ant colony optimization (ACO) algorithm called DACO to classify the cancer gene expression datasets, identifying the essential genes of… More >

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