Chun-ming Yang*, Shan Ji†, Yan Li‡, Li-ye Fu‡, Tao Jiang‡, Fan-dong Meng‡
Oncology Research, Vol.25, No.2, pp. 195-205, 2017, DOI:10.3727/096504016X14732772150424
Abstract Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current
therapies for RCC patients are inefficient due to the lack of diagnostic and therapeutic markers. The expression of novel tumor-associated kinases has the potential to dramatically shape tumor cell behavior. Identifying
tumor-associated kinases can lend insight into patterns of tumor growth and characteristics. In the present
study, we investigated the receptor tyrosine kinase-like orphan receptor 2 (Ror2), a new tumor-associated
kinase, in RCC primary tumors and cell lines. Knockdown of Ror2 expression in RCC cells with specific
shRNA significantly More >
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