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  • Open Access

    ARTICLE

    The Usefulness of Pretreatment MR-Based Radiomics on Early Response of Neoadjuvant Chemotherapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

    Piao Yongfeng*†‡§1, Jiang Chuner*¶#1, Wang Lei*†‡§, Yan Fengqin*†‡§, Ye Zhimin*†‡§, Fu Zhenfu*†‡§, Jiang Haitao*,**††, Jiang Yangming‡‡, Wang Fangzheng*†‡§

    Oncology Research, Vol.28, No.6, pp. 605-613, 2020, DOI:10.3727/096504020X16022401878096

    Abstract The aim of this study was to explore the predictive role of pretreatment MRI-based radiomics on early response of neoadjuvant chemotherapy (NAC) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients. Between January 2016 and December 2016, a total of 108 newly diagnosed NPC patients who were hospitalized in the Cancer Hospital of the University of Chinese Academy of Sciences were reviewed. All patients had complete data of enhanced MR of nasopharynx before treatment, and then received two to three cycles of TP-based NAC. After 2 cycles of NAC, enhanced MR of nasopharynx was conducted again. Compared with the enhanced MR images… More >

  • Open Access

    ARTICLE

    Development of an Ultrasonic Nomogram for Preoperative Prediction of Castleman Disease Pathological Type

    Xinfang Wang1, Lianqing Hong2, Xi Wu3, Jia He3, Ting Wang3,4,*, Hongbo Li5, Shaoling Liu6

    CMC-Computers, Materials & Continua, Vol.61, No.1, pp. 141-154, 2019, DOI:10.32604/cmc.2019.06030

    Abstract An ultrasonic nomogram was developed for preoperative prediction of Castleman disease (CD) pathological type (hyaline vascular (HV) or plasma cell (PC) variant) to improve the understanding and diagnostic accuracy of ultrasound for this disease. Fifty cases of CD confirmed by pathology were gathered from January 2012 to October 2018 from three hospitals. A grayscale ultrasound image of each patient was collected and processed. First, the region of interest of each gray ultrasound image was manually segmented using a process that was guided and calibrated by radiologists who have been engaged in imaging diagnosis for more than 5 years. In addition,… More >

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