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  • Open Access

    ARTICLE

    One-Step to Prepare Lignin Based Fluorescent Nanoparticles with Excellent Radical Scavenging Activity

    Xujing Zhang1, Hatem Abushammala2, Debora Puglia3, Binbao Lu1, Pengwu Xu1, Weijun Yang1,*, Piming Ma1

    Journal of Renewable Materials, Vol.12, No.5, pp. 895-908, 2024, DOI:10.32604/jrm.2024.049810

    Abstract Fluorescent nanomaterials have attracted much attention, due to their unique luminescent properties and promising applications in biomedical areas. In this study, lignin based fluorescent nanoparticles (LFNP) with high yield (up to 32.4%) were prepared from lignin nanoparticles (LNP) by one-pot hydrothermal method with ethylenediamine (EDA) and citric acid. Morphology and chemical structure of LFNP were investigated by SEM, FT-IR, and zeta potential, and it was found that the structure of LFNP changed with the increase of citric acid addition. LFNP showed the highest fluorescence intensity under UV excitation at wavelengths of 375–385 nm, with emission More > Graphic Abstract

    One-Step to Prepare Lignin Based Fluorescent Nanoparticles with Excellent Radical Scavenging Activity

  • Open Access

    REVIEW

    Review on marine collagen peptides induce cancer cell apoptosis, necrosis, and autophagy by reducing oxidized free radicals

    YINGHUA LUO1,#, YU ZHANG2,#, TONG ZHANG2,#, YANNAN LI2, HUI XUE2, JINGLONG CAO2, WENSHUANG HOU2, JIAN LIU2, YUHE CUI2, TING XU2, CHENGHAO JIN2,3,*

    BIOCELL, Vol.47, No.5, pp. 965-975, 2023, DOI:10.32604/biocell.2023.027729

    Abstract Marine collagen peptides (MCPs) are natural products prepared by hydrolyzing marine collagen protein through a variety of chemical methods or enzymes. MCPs have a range of structures and biological activities and are widely present in marine species. MCPs also have a small molecular weight, are easily modified, and absorbed by the body. These properties have attracted great interest from researchers studying antioxidant, anti-tumor, and anti-aging activities. MCPs of specific molecular weights have significant anti-tumor activity and no toxic side effects. Thus, MCPs have the potential use as anti-cancer adjuvant drugs. Free radicals produced by oxidation More >

  • Open Access

    ARTICLE

    Performance Improved of a Lime and Hemp-Based Concrete through the Addition of Metakaolin

    Suzanne Daher*, Amar Benazzouk, Haïkel Ben Hamed, Thierry Langlet

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.5, pp. 1091-1113, 2023, DOI:10.32604/fdmp.2023.020348

    Abstract This work describes in detail the experimental investigation of the physico-mechanical properties of nonstructural hemp concrete (usually used as insulating wall material) when the Air-lime based Tradial PF70 binder is partially replaced using Metakaolin. The objective is to reduce the amount of free Ca2+ ions in the binder as these are responsible for the degradation of vegetables particles and can therefore induce a loss of mechanical performances. In order to assess the effectiveness of pozzolanic reaction, amounts of 0%, 10%, and 20% vol. of Air-lime binder were replaced by the Metakaolin material, while testing the mechanical More >

  • Open Access

    ARTICLE

    Phytochemical Analysis and Antioxidant Activity of Crocus speciosus Leaves

    Olha Mykhailenko1,*, Ivan Bezruk1, Victoriia Volochai2, Volodymyr Mishchenko3, Liudas Ivanauskas4, Victoriya Georgiyants1

    Phyton-International Journal of Experimental Botany, Vol.91, No.1, pp. 207-221, 2022, DOI:10.32604/phyton.2022.016458

    Abstract The numerous studies indicate leaves of plants are a rich source of bioactive compounds that can be a valuable source of compounds used in the pharmaceutical and cosmetic industries. Aim of this study was to investigate the chemical composition and the antioxidant property of Crocus speciosus leaves. Primary phytochemical screening of C. speciosus leaves revealed the presence of some following compound categories such as phenolic compounds, aminoacids, saponins, proteins, tannins, triterpenoids, glycosides, polysaccharides. The total flavonoids and phenolic compounds content were determined spectrophotometrically and by HPLC-DAD and HPLC-MS. Antiradical activity was determined by ABTS radical-cation scavenging method,… More >

  • Open Access

    ARTICLE

    Analysis of Antioxidant Potential of Trigonella foenum-graecum (L.) Extract Against Tumorigenesis

    Shivangi Goyal, Sreemoyee Chatterjee, Nidhi Gupta*

    Oncologie, Vol.23, No.1, pp. 89-104, 2021, DOI:10.32604/Oncologie.2021.015234

    Abstract Background: Trigonella foenum-graecum Linn. has been extensively used for medicinal purposes. The current study deals with in vitro and in vivo correlation of free radical quenching activity and anticancer potential of seed extracts of Trigonella. Materials and methods: Antioxidant activity was evaluated against DPPH, NO and ABTS via in vitro radical scavenging assay. Cytotoxicity effect of Trigonella seed extract was studied in human embryonic kidney HEK 293 cell line by alamar blue assay. In vivo antioxidant activity in Swiss albino mice model was assessed by studying endogenous antioxidant enzymes such as GSH, GPx, SOD and LPO. Antitumor effect was observed by studying parameters… More >

  • Open Access

    ARTICLE

    Healing Effect and Underlying Mechanism of Silver Nanoparticles Prepared Using Carboxymethyl Chitosan under Solar Irradiation

    Yi Long1,#,* , Chunling Zhang2,#,*, Lan Chen3,#, Tietao Di2, Lu Chen2, Lisha Tang2, Kaizhong Luo2, Yu Yan1, Pingzhen Tong2, Jie Xiang4

    Journal of Renewable Materials, Vol.9, No.6, pp. 1075-1085, 2021, DOI:10.32604/jrm.2021.014555

    Abstract In our previous study, silver nanoparticles were prepared using AgNO3 and carboxymethyl chitosan (CMCS) which is commercially available with solar irradiation. In this study, the efficacy and safety of silver nanoparticles prepared by this method were evaluated for healing wounds in rats with diabetes. We also attempted to determine the underlying mechanism and influencing factors of the silver nanomaterial preparation method. Compared with growth factors, silver nanoparticles exhibit better healing effects for rats with diabetes. No remnant silver ions were detected in the major organs of these rats after the application of silver nanoparticles. Silver nanoparticles… More >

  • Open Access

    ARTICLE

    Understanding the Language of ISIS: An Empirical Approach to Detect Radical Content on Twitter Using Machine Learning

    Zia Ul Rehman1,2, Sagheer Abbas1, Muhammad Adnan Khan3,*, Ghulam Mustafa2, Hira Fayyaz4, Muhammad Hanif1,2, Muhammad Anwar Saeed5

    CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1075-1090, 2021, DOI:10.32604/cmc.2020.012770

    Abstract The internet, particularly online social networking platforms have revolutionized the way extremist groups are influencing and radicalizing individuals. Recent research reveals that the process initiates by exposing vast audiences to extremist content and then migrating potential victims to confined platforms for intensive radicalization. Consequently, social networks have evolved as a persuasive tool for extremism aiding as recruitment platform and psychological warfare. Thus, recognizing potential radical text or material is vital to restrict the circulation of the extremist chronicle. The aim of this research work is to identify radical text in social media. Our contributions are… More >

  • Open Access

    ARTICLE

    Prognostic Value of EGFR Expression for Patients With Stage III Colorectal Cancer Receiving Fluoropyrimidine Metronomic Maintenance Therapy After Radical Resection and Adjuvant Oxaliplatin-Based Chemotherapy

    Ching-Wen Huang*, Cheng-Jen Ma*†, Wei-Chih Su*, Yi-Ting Chen‡§, Hsiang-Lin Tsai, Yung-Sung Yeh*#, Tsung-Kun Chang*, Wen-Hung Hsu**††, Fang-Jung Yu**††, Jaw-Yuan Wang*¶‡‡§§¶¶##

    Oncology Research, Vol.28, No.7-8, pp. 701-714, 2020, DOI:10.3727/096504020X15986099915822

    Abstract This study evaluated the survival effects of metronomic maintenance therapy with oral fluoropyrimidine in patients with stage III colorectal cancer (CRC) according to epidermal growth factor receptor (EGFR) expression. We enrolled 197 patients with stage III CRC who had undergone radical resection and FOLFOX regimen adjuvant chemotherapy. The clinicopathological features and effects of metronomic maintenance therapy with oral capecitabine (daily dose of 850 mg/m2 , twice daily, on days 1–14 every 3 weeks for 6 months) on survival according to treatment group and EGFR expression were analyzed. By conducting an in vitro cell line study… More >

  • Open Access

    ARTICLE

    Tentative Identification of Phytochemicals and Antioxidant Activities during Fruit-Ripening on Chamaedorea radicalis Mart.

    Gerardo Montelongo-Ruíz1, Yolanda del Rocio Moreno-Ramírez1, María Cruz Juárez-Aragón1, Nohemí Niño-García2, Reyna Ivonne Torres-Acosta2, Torres-Castillo Jorge Ariel1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.2, pp. 361-373, 2020, DOI:10.32604/phyton.2020.08499

    Abstract This work aims to determine the phytochemical characterization of the pericarp of Chamaedorea radicalis Mart. fruit as a non-timber product with potential to obtain phytochemicals with potential applications in the industry. Fruit from C. radicalis were grouped in four ripening stages named as S1, S2, S3 and S4, according to maturity; S1 the most unripe stage and S4 the completely ripe stage. Determinations of total phenolic compounds, free radical scavenging activities and total flavonoid contents using spectrophotometric methods were done. Also, the tentative identification of phytochemicals during fruit ripening was done using UPLC-MS-MS. Total phenolic compound (TPC)… More >

  • Open Access

    ARTICLE

    Novel Sugar Based Acrylate: Synthesis, Characterization and Polymerization

    MERYEM KORUYUCUa, FEHMi SALTANa,b, GÖKHAN KÖKa, HAKAN AKATa, YEŞIM SALMANa,*

    Journal of Polymer Materials, Vol.36, No.3, pp. 207-216, 2019, DOI:10.32381/JPM.2019.36.03.1

    Abstract The present study has demonstrated that novel acrylic glycopolymers are successfully prepared by using monosaccharides containing an acrylate group (9-12). For this purpose, sugar based acrylate monomers were synthesized via ring opening method (Method B) and homopolymerization of this sugar oxypropylacrylates was performed using free radical polymerization. The characterization of all the monomers and polymers were verified by 1HNMR, 13CNMR, FTIR and GPC techniques. The Glass transition temperatures and thermal characteristics of the polymers were also analyzed by using DSC and TG techniques. The thermal stability of prepared polymers have changed with the stereochemistry of the More >

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