Junkai Chang*1, Weibo Xu*1, Guangchao Liu†, Xinyi Du*, Xiaodong Li*
Oncology Research, Vol.25, No.2, pp. 241-248, 2017, DOI:10.3727/096504016X14742891049118
Abstract Rab23, a novel member of the Rab GTPase family, was found to be implicated in the progression of some
human cancers. However, what role Rab23 plays in prostate cancer (PCa) remains to be illustrated. In the
present study, we investigated the expression pattern and roles of Rab23 in PCa. The study results showed
that Rab23 was upregulated in PCa tissues and cell lines. Moreover, downregulation of Rab23 remarkably
suppressed the proliferation, migration, and invasion of PCa cells. In addition, downregulation of Rab23 significantly downregulated the protein expression levels of Shh and Gli1. Furthermore, we found More >
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