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  • Open Access

    ARTICLE

    Learning Vector Quantization-Based Fuzzy Rules Oversampling Method

    Jiqiang Chen, Ranran Han, Dongqing Zhang, Litao Ma*

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5067-5082, 2024, DOI:10.32604/cmc.2024.051494

    Abstract Imbalanced datasets are common in practical applications, and oversampling methods using fuzzy rules have been shown to enhance the classification performance of imbalanced data by taking into account the relationship between data attributes. However, the creation of fuzzy rules typically depends on expert knowledge, which may not fully leverage the label information in training data and may be subjective. To address this issue, a novel fuzzy rule oversampling approach is developed based on the learning vector quantization (LVQ) algorithm. In this method, the label information of the training data is utilized to determine the antecedent… More >

  • Open Access

    ARTICLE

    An Interactive Collaborative Creation System for Shadow Puppets Based on Smooth Generative Adversarial Networks

    Cheng Yang1,2, Miaojia Lou2,*, Xiaoyu Chen1,2, Zixuan Ren1

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4107-4126, 2024, DOI:10.32604/cmc.2024.049183

    Abstract Chinese shadow puppetry has been recognized as a world intangible cultural heritage. However, it faces substantial challenges in its preservation and advancement due to the intricate and labor-intensive nature of crafting shadow puppets. To ensure the inheritance and development of this cultural heritage, it is imperative to enable traditional art to flourish in the digital era. This paper presents an Interactive Collaborative Creation System for shadow puppets, designed to facilitate the creation of high-quality shadow puppet images with greater ease. The system comprises four key functions: Image contour extraction, intelligent reference recommendation, generation network, and… More >

  • Open Access

    ARTICLE

    A Harmonic Approach to Handwriting Style Synthesis Using Deep Learning

    Mahatir Ahmed Tusher1, Saket Choudary Kongara1, Sagar Dhanraj Pande2, SeongKi Kim3,*, Salil Bharany4,*

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4063-4080, 2024, DOI:10.32604/cmc.2024.049007

    Abstract The challenging task of handwriting style synthesis requires capturing the individuality and diversity of human handwriting. The majority of currently available methods use either a generative adversarial network (GAN) or a recurrent neural network (RNN) to generate new handwriting styles. This is why these techniques frequently fall short of producing diverse and realistic text pictures, particularly for terms that are not commonly used. To resolve that, this research proposes a novel deep learning model that consists of a style encoder and a text generator to synthesize different handwriting styles. This network excels in generating conditional… More >

  • Open Access

    ARTICLE

    An Intrusion Detection Method Based on a Universal Gravitation Clustering Algorithm

    Jian Yu1,2,*, Gaofeng Yu3, Xiangmei Xiao1,2, Zhixing Lin1,2

    Journal of Cyber Security, Vol.6, pp. 41-68, 2024, DOI:10.32604/jcs.2024.049658

    Abstract With the rapid advancement of the Internet, network attack methods are constantly evolving and adapting. To better identify the network attack behavior, a universal gravitation clustering algorithm was proposed by analyzing the dissimilarities and similarities of the clustering algorithms. First, the algorithm designated the cluster set as vacant, with the introduction of a new object. Subsequently, a new cluster based on the given object was constructed. The dissimilarities between it and each existing cluster were calculated using a defined difference measure. The minimum dissimilarity was selected. Through comparing the proposed algorithm with the traditional Back More >

  • Open Access

    ARTICLE

    ShCTR1 Interacts with ShRBOH1 to Positively Regulate Aerenchyma Formation in Saussurea inversa through ROS Mediation

    Wubin Dai1, Xiuting Ju1,2, Guomin Shi1,2, Jialei Guo3,4, Tao He3,4,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 1023-1042, 2024, DOI:10.32604/phyton.2024.050066

    Abstract Saussurea inversa is one of the Tibetan medicine with developed aerenchyma. In this study, we investigated the function of the ShCTR1 gene related to the formation of aerenchyma. The study of the occurrence and formation of aerenchyma in S. inversa has certain theoretical significance in revealing the special mechanism of alpine plants adapting to the environment. The results of yeast two-hybrid experiments showed that S. inversa ShCTR1 interacted with the ShRBOH1, which is a key producer of reactive oxygen species (ROS), and it was hypothesized that ShCTR1 regulation of aerenchyma formation in S. inversa mainly mediated by ROS. Aerenchyma induction and… More >

  • Open Access

    ARTICLE

    Reversal of tamoxifen resistance by artemisinin in ER+ breast cancer: bioinformatics analysis and experimental validation

    ZHILI ZHUO#, DONGNI ZHANG#, WENPING LU*, XIAOQING WU, YONGJIA CUI, WEIXUAN ZHANG, MENGFAN ZHANG

    Oncology Research, Vol.32, No.6, pp. 1093-1107, 2024, DOI:10.32604/or.2024.047257

    Abstract Breast cancer is the leading cause of cancer-related deaths in women worldwide, with Hormone Receptor (HR)+ being the predominant subtype. Tamoxifen (TAM) serves as the primary treatment for HR+ breast cancer. However, drug resistance often leads to recurrence, underscoring the need to develop new therapies to enhance patient quality of life and reduce recurrence rates. Artemisinin (ART) has demonstrated efficacy in inhibiting the growth of drug-resistant cells, positioning art as a viable option for counteracting endocrine resistance. This study explored the interaction between artemisinin and tamoxifen through a combined approach of bioinformatics analysis and experimental… More > Graphic Abstract

    Reversal of tamoxifen resistance by artemisinin in ER+ breast cancer: bioinformatics analysis and experimental validation

  • Open Access

    ARTICLE

    Prediction of the Pore-Pressure Built-Up and Temperature of Fire-Loaded Concrete with Pix2Pix

    Xueya Wang1, Yiming Zhang2,3,*, Qi Liu4, Huanran Wang1

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2907-2922, 2024, DOI:10.32604/cmc.2024.050736

    Abstract Concrete subjected to fire loads is susceptible to explosive spalling, which can lead to the exposure of reinforcing steel bars to the fire, substantially jeopardizing the structural safety and stability. The spalling of fire-loaded concrete is closely related to the evolution of pore pressure and temperature. Conventional analytical methods involve the resolution of complex, strongly coupled multifield equations, necessitating significant computational efforts. To rapidly and accurately obtain the distributions of pore-pressure and temperature, the Pix2Pix model is adopted in this work, which is celebrated for its capabilities in image generation. The open-source dataset used herein… More >

  • Open Access

    ARTICLE

    CMAES-WFD: Adversarial Website Fingerprinting Defense Based on Covariance Matrix Adaptation Evolution Strategy

    Di Wang, Yuefei Zhu, Jinlong Fei*, Maohua Guo

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2253-2276, 2024, DOI:10.32604/cmc.2024.049504

    Abstract Website fingerprinting, also known as WF, is a traffic analysis attack that enables local eavesdroppers to infer a user’s browsing destination, even when using the Tor anonymity network. While advanced attacks based on deep neural network (DNN) can perform feature engineering and attain accuracy rates of over 98%, research has demonstrated that DNN is vulnerable to adversarial samples. As a result, many researchers have explored using adversarial samples as a defense mechanism against DNN-based WF attacks and have achieved considerable success. However, these methods suffer from high bandwidth overhead or require access to the target… More >

  • Open Access

    ARTICLE

    LDAS&ET-AD: Learnable Distillation Attack Strategies and Evolvable Teachers Adversarial Distillation

    Shuyi Li, Hongchao Hu*, Xiaohan Yang, Guozhen Cheng, Wenyan Liu, Wei Guo

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2331-2359, 2024, DOI:10.32604/cmc.2024.047275

    Abstract Adversarial distillation (AD) has emerged as a potential solution to tackle the challenging optimization problem of loss with hard labels in adversarial training. However, fixed sample-agnostic and student-egocentric attack strategies are unsuitable for distillation. Additionally, the reliability of guidance from static teachers diminishes as target models become more robust. This paper proposes an AD method called Learnable Distillation Attack Strategies and Evolvable Teachers Adversarial Distillation (LDAS&ET-AD). Firstly, a learnable distillation attack strategies generating mechanism is developed to automatically generate sample-dependent attack strategies tailored for distillation. A strategy model is introduced to produce attack strategies that… More >

  • Open Access

    ARTICLE

    Anemarsaponin B mitigates acute pancreatitis damage in mice through apoptosis reduction and MAPK pathway modulation

    YI HU1,#, ZHONGYANG REN2,#, ZHENGZHONG ZHAO1, YONGJIA HUANG3, WANTING HUANG3, JIE LIU3,*, LING DING3,*

    BIOCELL, Vol.48, No.5, pp. 745-758, 2024, DOI:10.32604/biocell.2024.049140

    Abstract Background: Acute pancreatitis (AP), known for its rapid onset and significant incidence and mortality rates, presents a clinical challenge due to the limited availability of effective treatments and preventive measures. Anemarsaponin B (ASB) has emerged as a potential therapeutic agent, demonstrating capabilities in reducing immune inflammation, positioning it as a promising candidate for AP treatment. Methods: We investigated the effects of ASB on AP in mice, induced by caerulein and lipopolysaccharide (LPS). Peripheral blood samples were collected 24 h post-induction with caerulein to assess of key biomarkers including lipase, amylase, TNF-α, IL-1β, IL-6, SOD, and… More >

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