Yanli Wang*, Jia Li†, Chunling Xu†, Xiaomeng Zhang†
Oncology Research, Vol.28, No.7-8, pp. 823-825, 2020, DOI:10.3727/096504021X16240202940021
Abstract Increasing evidence indicates that the dysregulation of microRNAs is associated with the development and
progression of various cancers. MicroRNA-139-5p (miR-139-5p) has been reported to have a tumor suppressive role in many types of cancers. The role of miR-139-5p in ovarian cancer (OC) is poorly understood. The
purpose of the present study was to explore the expression of miR-139-5p and its function in OC. The results
showed that miR-139-5p expression was markedly downregulated in OC tissues and cell lines. In addition,
underexpression of miR-139-5p was significantly associated with FIGO stage, lymph mode metastasis, and
poor overall survival of OC patients. Functional… More >
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