Shengzhe Ma1,#, Xiaoming Zhu1,#, Cheng Xin1,#, Fuao Cao1, Mengnan Xu1, Xiangling Han1, Jinke Sui3,*, Wenjun Chang2,*, Wei Zhang1,*
Oncologie, Vol.24, No.4, pp. 823-833, 2022, DOI:10.32604/oncologie.2022.025411
- 31 December 2022
Abstract Background: Reticulocalbin 3 (RCN3) has been associated with several malignancies. However, its role in colorectal cancer (CRC) remains controversial. Thus, this study aimed to investigate the role of RCN3 in CRC prognosis. Methods: The clinical significance of RCN3 expression in CRC was evaluated in a large cohort of
483 patients. Normal tissues, carcinoma, para-carcinoma, adenoma, and metastatic tissues were evaluated by
immunohistochemistry. We investigated the association between RCN3 expression and CRC occurrence in
tumors and other tissues. Prognostic factors were also evaluated by Kaplan-Meier survival analysis and the
Cox regression model. Results: RCN3 was significantly overexpressed in CRC… More >
Login
Register
