Li Wan1, Lin Zhang1, Kai Fan, Zai-Xing Cheng, Quan-Chao Sun, Jian-Jun Wang
Oncology Research, Vol.24, No.3, pp. 161-170, 2016, DOI:10.3727/096504016X14618564639178
Abstract As a newly identified oncogenic long noncoding RNA (lncRNA), prostate cancer-associated transcript 6
(PCAT6) promoted cellular proliferation and colony formation of prostate cancer. However, the biological
function of PCAT6 in lung cancer is still largely unknown. In this study, we found that PCAT6 is significantly
increased in cancer tissues compared to normal tissues and positively correlates with metastasis of lung cancer
in patients. We then examined PCAT6 expression in lung cancer cell lines and identified that PCAT6 expression was significantly elevated in lung cancer cells compared to normal human bronchial epithelial (NHBE)
cells, especially in… More >
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