Dong Yang, Jian-Jun Wang, Jin-Song Li, Qian-Yu Xu
Oncology Research, Vol.26, No.4, pp. 519-528, 2018, DOI:10.3727/096504017X15000757094686
Abstract Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancer cases. Absence of miR-103
has recently been identified to be associated with metastatic capacity of primary lung tumors. However, the
exact role of miR-103 in NSCLC and the molecular mechanism are unclear. In the present study, we showed
that miR-103 expression was reduced in NSCLC tissues and cells. miR-103 expression was negatively correlated with tumor size and stage. The overall survival was longer in patients with higher miR-103 level than
in those with lower miR-103 expression. miR-103 inhibited cell proliferation in A549… More >
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