Dagang Li*, Huizong Li†, Yuping Yang*, Le Kang*
Oncology Research, Vol.26, No.4, pp. 537-546, 2018, DOI:10.3727/096504017X15009792179602
Abstract Long noncoding RNA urothelial carcinoma-associated 1 (lncRNA UCA1) has gained more attention in recent
years due to its oncogenic roles in various cancers. MicroRNA-144 (miR-144) participates in the regulation of
the growth of many cancer cells. This study investigated the interaction between lncRNA UCA1 and miR-144
in lung cancer cells. The potential downstream protein of miR-144 was also assessed. Our results found that
lncRNA UCA1 was highly expressed in human lung cancer A549, H517, H4006, H1299, and H1650 cells compared to normal embryonic lung WI-38 and HEL-1 cells. Knockdown of lncRNA UCA1 significantly inhibited
lung More >
Login
Register
