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Search Results (15)
  • Open Access

    ARTICLE

    A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase (DLAT) as a novel prognostic biomarker in pan-cancer and glioma

    HUI ZHOU#, ZHENGYU YU#, JING XU, ZHONGWANG WANG, YALI TAO, JINJIN WANG, PEIPEI YANG, JINRONG YANG*, TING NIU*

    Oncology Research, Vol.32, No.12, pp. 1903-1919, 2024, DOI:10.32604/or.2024.048138 - 13 November 2024

    Abstract Background: Dihydrolipoamide S-acetyltransferase (DLAT) is a subunit of the pyruvate dehydrogenase complex (PDC), a rate-limiting enzyme complex, that can participate in either glycolysis or the tricarboxylic acid cycle (TCA). However, the pathogenesis is not fully understood. We aimed to perform a more systematic and comprehensive analysis of DLAT in the occurrence and progression of tumors, and to investigate its function in patients’ prognosis and immunotherapy. Methods: The differential expression, diagnosis, prognosis, genetic and epigenetic alterations, tumor microenvironment, stemness, immune infiltration cells, function enrichment, single-cell analysis, and drug response across cancers were conducted based on multiple computational… More > Graphic Abstract

    A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase <i>(DLAT)</i> as a novel prognostic biomarker in pan-cancer and glioma

  • Open Access

    ARTICLE

    Morphometric Attributes of Two Native Forage Species According to Water Source Distance in Semiarid Central Grasslands of Argentina

    Carla Etel Suárez1,*, María Sol Rossini1,3, Ernesto Francisco Atilio Morici1, Héctor Daniel Esterlich1,2

    Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 2063-2074, 2024, DOI:10.32604/phyton.2024.053193 - 30 August 2024

    Abstract The semiarid grasslands of Argentina’s central region have been modified by domestic livestock grazing, both in their composition and structure. The increase in the proportion of woody and non-forage species and the decrease in forage species are some of the most evident results of this process. There is limited available information about the effect of differential grazing pressures on morphometric attributes of native species, and it also depends on the life histories of the species in this grassland. The objective of this work was to evaluate some morphometric aspects in the grasses Poa ligularis Nees ex… More >

  • Open Access

    ARTICLE

    On Designs of Decentralized Reputation Management for Permissioned Blockchain Networks

    Jinyu Chen1, Long Shi1,*, Qisheng Huang2, Taotao Wang3, Daojing He4

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1755-1773, 2024, DOI:10.32604/cmes.2023.046826 - 29 January 2024

    Abstract In permissioned blockchain networks, the Proof of Authority (PoA) consensus, which uses the election of authorized nodes to validate transactions and blocks, has been widely advocated thanks to its high transaction throughput and fault tolerance. However, PoA suffers from the drawback of centralization dominated by a limited number of authorized nodes and the lack of anonymity due to the round-robin block proposal mechanism. As a result, traditional PoA is vulnerable to a single point of failure that compromises the security of the blockchain network. To address these issues, we propose a novel decentralized reputation management… More > Graphic Abstract

    On Designs of Decentralized Reputation Management for Permissioned Blockchain Networks

  • Open Access

    ARTICLE

    Blockchain-Based Cognitive Computing Model for Data Security on a Cloud Platform

    Xiangmin Guo1,2, Guangjun Liang1,2,*, Jiayin Liu1,2, Xianyi Chen3,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3305-3323, 2023, DOI:10.32604/cmc.2023.044529 - 26 December 2023

    Abstract Cloud storage is widely used by large companies to store vast amounts of data and files, offering flexibility, financial savings, and security. However, information shoplifting poses significant threats, potentially leading to poor performance and privacy breaches. Blockchain-based cognitive computing can help protect and maintain information security and privacy in cloud platforms, ensuring businesses can focus on business development. To ensure data security in cloud platforms, this research proposed a blockchain-based Hybridized Data Driven Cognitive Computing (HD2C) model. However, the proposed HD2C framework addresses breaches of the privacy information of mixed participants of the Internet of… More >

  • Open Access

    ARTICLE

    Computation of PoA for Selfish Node Detection and Resource Allocation Using Game Theory

    S. Kanmani1,*, M. Murali2

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 2583-2598, 2023, DOI:10.32604/csse.2023.037265 - 28 July 2023

    Abstract The introduction of new technologies has increased communication network coverage and the number of associating nodes in dynamic communication networks (DCN). As the network has the characteristics like decentralized and dynamic, few nodes in the network may not associate with other nodes. These uncooperative nodes also known as selfish nodes corrupt the performance of the cooperative nodes. Namely, the nodes cause congestion, high delay, security concerns, and resource depletion. This study presents an effective selfish node detection method to address these problems. The Price of Anarchy (PoA) and the Price of Stability (PoS) in Game More >

  • Open Access

    ARTICLE

    Proof of Activity Protocol for IoMT Data Security

    R. Rajadevi1, K. Venkatachalam2, Mehedi Masud3, Mohammed A. AlZain4, Mohamed Abouhawwash5,6,*

    Computer Systems Science and Engineering, Vol.44, No.1, pp. 339-350, 2023, DOI:10.32604/csse.2023.024537 - 01 June 2022

    Abstract The Internet of Medical Things (IoMT) is an online device that senses and transmits medical data from users to physicians within a time interval. In, recent years, IoMT has rapidly grown in the medical field to provide healthcare services without physical appearance. With the use of sensors, IoMT applications are used in healthcare management. In such applications, one of the most important factors is data security, given that its transmission over the network may cause obtrusion. For data security in IoMT systems, blockchain is used due to its numerous blocks for secure data storage. In… More >

  • Open Access

    ARTICLE

    Lightweight Direct Acyclic Graph Blockchain for Enhancing Resource-Constrained IoT Environment

    Salaheddine Kably1,2,*, Mounir Arioua1, Nabih Alaoui2

    CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 5271-5291, 2022, DOI:10.32604/cmc.2022.020833 - 14 January 2022

    Abstract Blockchain technology is regarded as the emergent security solution for many applications related to the Internet of Things (IoT). In concept, blockchain has a linear structure that grows with the number of transactions entered. This growth in size is the main obstacle to the blockchain, which makes it unsuitable for resource-constrained IoT environments. Moreover, conventional consensus algorithms such as PoW, PoS are very computationally heavy. This paper solves these problems by introducing a new lightweight blockchain structure and lightweight consensus algorithm. The Multi-Zone Direct Acyclic Graph (DAG) Blockchain (Multizone-DAG-Blockchain) framework is proposed for the fog-based IoT… More >

  • Open Access

    ARTICLE

    Presenting a Signal to Noise Ratio Model Based on the Combined Effect of Sound Pressure Level/frequency, Exposure Time and Oral Potassium: Experimental Study in Rats

    Parvin Nassiri1, Sajad Zare2,*, Mohammad Reza Monazzam1, Akram Pourbakht3, Rasoul Hemmatjo4, Hossein ElahiShirvan2

    Sound & Vibration, Vol.54, No.1, pp. 17-25, 2020, DOI:10.32604/sv.2020.08395 - 01 March 2020

    Abstract Exposure to noise can lead to anatomical, nonauditory, and auditory impacts. The auditory influence of noise exposure is manifested in the form of Noise-induced hearing loss (NIHL). The current study aimed at present a signal to noise ratio model of otoacoustic emission of rats’ ears in the light of the combined effect of sound pressure level, sound frequency, exposure time, and potassium concentration of the used water. In total, 36 adult male rates, whose age varied from 3 to 4 months and had a weight of 200 ± 50 g, were randomly divided into 12… More >

  • Open Access

    ARTICLE

    Stem and root anatomy of Mnesithea selloana (Hack.) de Koning & Sosef

    Moya ME1,2, AA Galussi1,2, N Sattler2, MS Fontana2, YG Gillij1,2

    Phyton-International Journal of Experimental Botany, Vol.87, pp. 231-235, 2018, DOI:10.32604/phyton.2018.87.231

    Abstract The objective of this study was to analyze the anatomy of stems and roots of Mnesithea selloana. Free hand cross sections were made from fresh material of reproductive stems and adventitious roots; they were colored with safranin and mounted on glycerin jelly. Observations were made using an Olympus CH2 light microscope and photographed. In cross section, the stems were circular towards the distal end of the synflorescence and semicircular toward the proximal end, and have two ribs. A uniseriate, continuous epidermis presenting a smooth and thick cuticle and no hairs was observed. Parenchyma cells increased in… More >

  • Open Access

    ARTICLE

    Morphological, molecular and pathogenic diagnostic of fungi in lawn’s root and neck in Mexico

    García-Munguía CA1, M Acosta-Ramos2, O Vázquez-Martinez3, M Pérez-Sato5, A García-Munguía4, O García-Munguía6, AM García-Munguía3

    Phyton-International Journal of Experimental Botany, Vol.86, pp. 258-264, 2017, DOI:10.32604/phyton.2017.86.258

    Abstract The illnesses that cause root and neck rot in golf courses constitute a limiting factor for grass development worldwide. This is mainly true when management guidelines are not conducted. Our research was conducted in the Golf Club “Mexico”, located in Mexico, D.F. Isolates were taken from plants that presented yellowing symptoms and root and neck rot. The identified pathogenic fungi, isolated from axenic media, were Giberella avenacea, Fusarium oxysporum, F. oxysporum f. sp. cubense and Pythium ultimum. The molecular characterization showed a comparison of the DNA-obtained sequences which was morphologically determined as F. avenaceum and was molecularly corroborated as… More >

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