Wei Song*, Jia-Zhuan Mei†, Mingzhi Zhang‡
Oncology Research, Vol.28, No.9, pp. 971-972, 2020, DOI:10.3727/096504022X16414984936791
Abstract Accumulating evidence has indicated that long noncoding RNA (lncRNA) PlncRNA-1 plays an important
regulatory role in cancers. However, the expression and biological functions of PlncRNA-1 in colorectal cancer
(CRC) are still unclear. In the present study, we determined the expression of PlncRNA-1 in CRC and explored
the function of PlncRNA-1 on CRC cell progression. The results showed that PlncRNA-1 was significantly
increased in CRC tissues and cell lines; high PlncRNA-1 expression was associated with depth of invasion,
lymph node metastasis, and TNM stage of CRC patients. Kaplan–Meier curve analysis showed that patients
with high PlncRNA-1 expression had a poor overall… More >
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