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  • Open Access

    REVIEW

    Monocyte Phenotypic Plasticity in Peripheral Artery Disease: From Pathophysiology to Therapeutic Targets

    Gizem Kaynar Beyaz1,*, Ahmet Kirbas2, Sevgi Kalkanli Tas1

    BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072368 - 23 January 2026

    Abstract Peripheral artery disease (PAD) remains a significant global health issue, with current treatments primarily focused on relieving symptoms and addressing macrovascular issues. However, critical immunoinflammatory mechanisms are often overlooked. Recent evidence suggests that monocyte phenotypic plasticity plays a central role in PAD development, affecting atherogenesis, plaque progression, ischemia-reperfusion injury, and chronic ischemic remodeling. This narrative review aims to summarize the latest advances (2023–2025) in understanding monocyte diversity, functional states, and their changes throughout different stages of PAD. We discuss both established and emerging biomarkers, such as circulating monocyte subset proportions, functional assays, immune checkpoint expression, More >

  • Open Access

    ARTICLE

    Growth and production characters of elymus cylindricus in different shortening heading time

    Chengcheng Li1, Chan Zhou2, Yunfei Yang1

    Phyton-International Journal of Experimental Botany, Vol.88, No.1, pp. 55-61, 2019, DOI:10.32604/phyton.2019.04577

    Abstract Ramet modules in a certain population differ in terms of functions, which accounts for different contributions of the same ramets. Shortening heading time brings about different contributions of such modules. Ramets heading one after another were treated as a continuum in respective cohorts of Elymus cylindricus aged two. The reproductive ramets that head earlier were marked with tags every four days during the whole heading stage from the beginning to the end, after which all the labeled ramets at the maturity period were gathered. The results showed that, the height and biomass of ramets, the… More >

  • Open Access

    ARTICLE

    Patterns of Leymus chinensis in response to grazing exclusion across two steppe habitats in Inner Mongolia: implications for phenotypic plasticity

    Shi G1, ZY Liu1, T Baoyin1, J Sun2, JJ Duan3, XL Li3, GF Yang4

    Phyton-International Journal of Experimental Botany, Vol.87, pp. 236-241, 2018, DOI:10.32604/phyton.2018.87.236

    Abstract Plant functional traits and their effects on rangeland ecosystem function have received much attention by ecologists. However, the importance of functional traits and the interactive effects of grazing exclusion and climate are poorly understood. This study, therefore, aimed to analyse the response of Leymus chinensis functional traits in long-term grazing exclusion in different habitats (rainless typical steppe and rainy meadow steppe). This study showed that although the sensitivity and variability of different traits were similar in two steppe habitats, phenotypic plasticity of L. chinensis in meadow steppe was significantly higher than typical steppes. With the increased degree More >

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