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  • Open Access

    ARTICLE

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

    JIE DUAN, AIDONG GU*, WEI CHEN, CHANGHAO CHEN, FANGNAN SONG, FAXI CHEN, FANGFANG JIANG, HUIWEN XING

    BIOCELL, Vol.47, No.12, pp. 2609-2615, 2023, DOI:10.32604/biocell.2023.042472 - 27 December 2023

    Abstract Objective: This study aims to analyze the clinical significance and mechanism of nuclear factor erythroid 2-related factor 2 (NRF2) and glutathione peroxidase 4 (GPX4) in primary hepatic carcinoma (PHC). Methods: The expression of NRF2 and GPX4 in peripheral blood of patients with PHC was determined to analyze the diagnostic value of the two combined for PHC. The prognostic significance of NRF2 and GPX4 was evaluated by 3-year follow-up. Human liver epithelial cells THLE-2 and human hepatocellular carcinoma cells HepG2 were purchased, and the expression of NRF2 and GPX4 in the cells was determined. NRF2 and GPX4… More > Graphic Abstract

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

  • Open Access

    ARTICLE

    Effects of Plant Extracts and Beauveria bassiana on the Activity of Defense-Related Enzymes in Solanum lycopersicum L. during Interaction with Fusarium oxysporum f. sp. lycopersici

    José Adrian Perez-Robles, Carlos Alberto Lecona-Guzmán*, Víctor Manuel Ruíz-Valdiviezo, Joaquín Adolfo Montes-Molina*

    Phyton-International Journal of Experimental Botany, Vol.92, No.9, pp. 2503-2518, 2023, DOI:10.32604/phyton.2023.029784 - 28 July 2023

    Abstract The objective to this work was to evaluate the enzymatic activity in the culture of Solanum lycopersicum L. infected with Fusarium oxysporum after the combined application of Beauveria bassiana and plant extracts. Solanum lycopersicum plantlets were transplanted 15 days after the emergency. Five days after transplanting, Beauveria bassiana spores were applied at a concentration of 1 × 107 spores mL−1 onto soil (along with A. indica (N) and P. auritum (H) leaf extracts) where S. lycopersicum plants were planted. Eight days after transplanting, spores of F. oxysporum strain were applied at a concentration of 1 × 106 spores mL−1 to soil where S. lycopersicum plants were growing.… More >

  • Open Access

    ARTICLE

    Proline and Oxidative Metabolism in Young Pecan Trees Associated with Sulphate Accumulation

    Dalila Jacqueline Escudero-Almanza1, Oscar Cruz-Alvarez1, Ofelia Adriana Hernández-Rodríguez1, Juan Luis Jacobo-Cuellar1, Esteban Sánchez-Chávez2, Pablo Preciado-Rángel3, Dámaris Leopoldina Ojeda-Barrios1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.6, pp. 1141-1152, 2022, DOI:10.32604/phyton.2022.019129 - 14 February 2022

    Abstract Pecan [Carya illinoinensis (Wangenh.) K. Koch.] is a deciduous tree whose fruits (nuts) are of high economic value and offer excellent nutritional benefits. However, soils high in sulphates can limit its growth and development. Working with 5-year-old trees of ‘Western Schley’ pecan grown in soils high in sulphates, the levels of proline and oxidative metabolism were recorded in the leaflets. Results showed that different levels of visible leaflet damage (‘sufficiency’, ‘low’, ‘moderate’ or ‘severe’) were associated with different levels of leaflet sulphates (mg kg−1): ‘sufficiency’ (≤40), ‘low’ (41–60), ‘moderate’ (61–80) and ‘severe’ (80–100). ‘Severe’ sulphate damage was… More >

  • Open Access

    VIEWPOINT

    Nitric oxide and hydrogen sulfide share regulatory functions in higher plant events

    FRANCISCO J. CORPAS*, SALVADOR GONZÁLEZ-GORDO, MARTA RODRÍGUEZ-RUIZ, MARÍA A. MUÑOZ-VARGAS, JOSÉ M. PALMA

    BIOCELL, Vol.46, No.1, pp. 1-5, 2022, DOI:10.32604/biocell.2021.017300 - 29 September 2021

    Abstract Nitric oxide (NO) and hydrogen sulfide (H2S) are two molecules that share signaling properties in plant and animal cells. NO and H2S originate two families of derived molecules designated reactive nitrogen and sulfur species (RNS and RSS, respectively). These molecules are responsible for certain protein regulatory processes through posttranslational modifications (PTMs), being the most remarkable S-nitrosation and persulfidation, which affect the thiol group of cysteine residues. NO and H2S can also exert regulatory functions due to their interaction through the iron present in proteins that contain heme groups or iron-sulfur clusters, as reported mainly in animal cells. More >

  • Open Access

    ARTICLE

    Stress Ameliorative Effects of Indole Acetic Acid on Hordeum vulgare L. Seedlings Subjected to Zinc Toxicity

    Monika Sood1, Shanti S. Sharma1, Joginder Singh1, Ram Prasad2,3,*, Dhriti Kapoor1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 71-86, 2020, DOI:10.32604/phyton.2020.07180 - 01 March 2020

    Abstract The heavy metals present in the environment accumulate in the plants and affect their productivity and yield. By entering the food chain, metals cause several serious health problems in human beings as well as in other organisms. Indole acetic acid (IAA) is known to act as a signaling molecule between symbiotic association of metal accumulating plants and plant growth promoting rhizobacteria (PGPR). Present study demonstrated a protective role of IAA against surplus Zinc (Zn)-induced toxicity to Hordeum vulgare seedlings. Elevated Zn concentrations suppressed the plant growth, caused a reduction in leaf relative water contents (RWC) and More >

  • Open Access

    ARTICLE

    Pharmacotherapy for patent ductus arteriosus closure

    John M. Ferguson

    Congenital Heart Disease, Vol.14, No.1, pp. 52-56, 2019, DOI:10.1111/chd.12715

    Abstract Even though up to 60% of premature infants less than 28 weeks gestation develop persistent patent ductus arteriosus (PDA), there remains controversy regarding if, when, and how to close the PDA. Failure to close the PDA has been associated with significant morbidity but no cause‐and‐effect has been proven for short‐term or long‐term outcomes in modern times. Surgical closure has the advantage of eliminating the PDA, but short‐term complications and long‐term adverse outcomes are worrisome. Intravenous indomethacin has been the “gold standard” for pharmacologic treatment over the past 40 years with high closure rates and decreased More >

  • Open Access

    ARTICLE

    Growth and biochemical responses of moringa (Moringa oleifera L.) to vermicompost and phosphate rock under water stress conditions

    Abud-Archila M1, AK Espinosa-Arrioja1, T González-Soto2, VF Gutiérrez-Oliva1, V Ruíz-Valdiviezo1, D González-Mendoza2, L Rodríguez-Hernández3, FA Gutiérrez-Miceli1

    Phyton-International Journal of Experimental Botany, Vol.87, pp. 209-215, 2018, DOI:10.32604/phyton.2018.87.209

    Abstract The aim of this investigation was to analyze the effect of vermicompost and phosphate rock on plant growth and biochemical responses of Moringa oleifera exposed to water deficit and waterlogging conditions. Treatments included 152 g of vermicompost (V) and 1.3 g of phosphate rock (PR) added to each cultivation bag. Control was prepared with 2.3 g of urea. All treatments were irrigated under different watering conditions [water deficit: irrigated at 20% water holding capacity (WHC); control (40% WHC) and waterlogging (60% WHC)]. The overall average in plant height was 90, 86 and 68 cm, whereas chlorophyll… More >

  • Open Access

    ARTICLE

    Biomechanical proposal as a cause of incomplete seed and pericarp development of the sunflower (Helianthus annuus L.) fruits

    Hernández LF1,2, PM Bellés3, MA Bidegain4,5, PD Postemsky4

    Phyton-International Journal of Experimental Botany, Vol.87, pp. 198-208, 2018, DOI:10.32604/phyton.2018.87.198

    Abstract Absence or underdevelopment of sunflower fruits come usually from failure in fertilization, stresses as well as physiological and morphological defects in the ovary. Thigmomorphogenesis has never been included as a possible cause. We have previously shown that a 2-3 day fertilization shift can occur between neighboring florets in the sunflower capitulum. It is proposed here that those ovaries with advanced fertilization can generate a significant radial and axial compressive stress on ovaries with delayed fertilization. This mechanical stimulus could be strong enough to trigger a thigmo response that affects further ovary development. In vivo tests… More >

  • Open Access

    ARTICLE

    Selenium invoked antioxidant defense system in Azolla caroliniana plant

    Hassan AMA, EM Mostafa

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 262-269, 2016, DOI:10.32604/phyton.2016.85.262

    Abstract Plants of Azolla caroliniana were treated with different selenium concentrations (0, 1, 2, 5, 7, 10 ppm) for seven days. Selenium (Se) content in Azolla plants increased significantly with increasing Se concentrations in the culture media up to 5 ppm. This indicated that Azolla plants were a good accumulator for Se. Selenium accumulation determined changes in Azolla biomass, doubling time and relative growth rates. Treatment of Azolla plants with low concentrations of Se (1 ppm) resulted in a significant increase in biomass. This was accompanied by a reduction in hydrogen peroxide and malondialdehyde (MDA) contents; the decrease percentages… More >

  • Open Access

    ARTICLE

    Antimalarial drug artesunate aff ords protection against carrageenan induced acute infl ammation in rat

    Vijay L. KUMAR1 *, B. GURUPRASAD1, Priyanka CHAUDHARY2

    BIOCELL, Vol.38, No.1, pp. 1-6, 2014, DOI:10.32604/biocell.2014.38.001

    Abstract Artesunate, an antimalarial drug, has been shown to inhibit the release of inflammatory mediators in various disease conditions. The present study was carried out to evaluate the anti-edematogenic effect of artesunate in the rat paw edema model. Inflammation was induced in the hind paw of rat by sub-plantar injection of 0.1 mL of 0.5% carrageenan and the paw volume was measured up to a fixed mark just before the injection and then after 3 h. The difference in two volumes gave a measure of edema formation. At 3h the level of TNF-α, PGE2 and myeloperoxidase More >

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