Hsien-Tsung Lu^1,2, Ching-Chi Hsu^3,*, Qi-Quan Jian³, Wei-Ting Chen⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.2, pp. 1883-1898, 2025, DOI:10.32604/cmes.2025.057675 - 27 January 2025

Abstract Reconstruction of a traumatic distal femur defect remains a therapeutic challenge. Bone defect implants have been proposed to substitute the bone defect, and their biomechanical performances can be analyzed via a numerical approach. However, the material assumptions for past computational human femur simulations were mainly homogeneous. Thus, this study aimed to design and analyze scaffolds for reconstructing the distal femur defect using a patient-specific finite element modeling technique. A three-dimensional finite element model of the human femur with accurate geometry and material distribution was developed using the finite element method and material mapping technique. An… More > Graphic Abstract

J.B. Alford¹, D.C. Simkins¹, R.A. Rembert¹, L. Hoyte, MD²

CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.2, pp. 129-149, 2014, DOI:10.3970/cmes.2014.098.129

Abstract Mechanical deformation of tissues in the female pelvic floor is believed to be central to understanding a number of important aspects of women’s health, particularly pelvic floor dysfunction. A 2008 study of US women reported the prevalence of pelvic floor disorders in the 20 and 39 years range as 9.7% with the prevalence increasing with age until it reaches roughly 50% in the 80 and older age group [Nygaard, Barber, Burgio, and et al (2008)]. Clinical observation indicates a strong correlation between problems such as pelvic organ prolapse/urinary incontinence and vaginal childbirth. It is thought… More >

Dalin Tang^*, Chun Yang^†, Tal Geva^‡,§, Pedro J. del Nido^¶

Molecular & Cellular Biomechanics, Vol.4, No.3, pp. 159-176, 2007, DOI:10.3970/mcb.2007.004.159

Abstract A single-layer isotropic patient-specific right/left ventricle and patch (RV/LV/Patch) combination model with fluid-structure interactions (FSI) was introduced in our previous papers to evaluate and optimize human pulmonary valve replacement/insertion (PVR) surgical procedure and patch design. In this paper, an active anisotropic model with two-layer structure for ventricle wall and tissue fiber orientation was introduced to improve previous isotropic model for more accurate assessment of RV function and potential application in PVR surgery and patch design. A material-stiffening approach was used to model active heart contraction. The computational models were used to conduct ``virtual (computational)'' surgeries More >