YUSHI YANG^1,#, CHUJIAO HU^2,#, SHAN LEI³, XIN BAO³, ZHIRUI ZENG^3,*, WENPENG CAO^4,*

Oncology Research, Vol.32, No.12, pp. 1921-1934, 2024, DOI:10.32604/or.2024.046191 - 13 November 2024

Abstract Background: The heterogeneity of prognosis and treatment benefits among patients with gliomas is due to tumor microenvironment characteristics. However, biomarkers that reflect microenvironmental characteristics and predict the prognosis of gliomas are limited. Therefore, we aimed to develop a model that can effectively predict prognosis, differentiate microenvironment signatures, and optimize drug selection for patients with glioma. Materials and Methods: The CIBERSORT algorithm, bulk sequencing analysis, and single-cell RNA (scRNA) analysis were employed to identify significant cross-talk genes between M2 macrophages and cancer cells in glioma tissues. A predictive model was constructed based on cross-talk gene expression, and… More >

Priyambada Praharaj^1,*, Chandrakant R. Sonawane^2,*, Arunkumar Bongale²

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.3, pp. 2021-2064, 2024, DOI:10.32604/cmes.2024.056289 - 31 October 2024

Abstract This paper represents a detailed and systematic review of one of the most ongoing applications of computational fluid dynamics (CFD) in biomedical applications. Beyond its various engineering applications, CFD has started to establish a presence in the biomedical field. Cardiac abnormality, a familiar health issue, is an essential point of investigation by research analysts. Diagnostic modalities provide cardiovascular structural information but give insufficient information about the hemodynamics of blood. The study of hemodynamic parameters can be a potential measure for determining cardiovascular abnormalities. Numerous studies have explored the rheological behavior of blood experimentally and numerically.… More >

Wen Zhang^1,2, Ting Wu^1,2, Xijian Chen^1,3, Hong Luo^1,2,*, Yifei Li^1,4,*

Congenital Heart Disease, Vol.19, No.4, pp. 399-406, 2024, DOI:10.32604/chd.2024.055178 - 31 October 2024

Abstract This article has no abstract. More >

Hamed Taherdoost^1,2,3,4,*

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 79-104, 2024, DOI:10.32604/cmc.2024.054378 - 15 October 2024

Abstract Technical and accessibility issues in hospitals often prevent patients from receiving optimal mental and physical health care, which is essential for independent living, especially as societies age and chronic diseases like diabetes and cardiovascular disease become more common. Recent advances in the Internet of Things (IoT)-enabled wearable devices offer potential solutions for remote health monitoring and everyday activity recognition, gaining significant attention in personalized healthcare. This paper comprehensively reviews wearable healthcare technology integrated with the IoT for continuous vital sign monitoring. Relevant papers were extracted and analyzed using a systematic numerical review method, covering various More >

EGOR V. BATOROV^1,2,*, ALISA D. INESHINA², TATIANA A. ARISTOVA³, VERA V. DENISOVA³, SVETLANA A. SIZIKOVA³, DARIA S. BATOROVA³, GALINA Y. USHAKOVA³, EKATERINA Y. SHEVELA¹, ELENA R. CHERNYKH¹

Oncology Research, Vol.32, No.10, pp. 1575-1587, 2024, DOI:10.32604/or.2024.047893 - 18 September 2024

Abstract Background: Immune checkpoint ligand-receptor interactions appear to be associated with multiple myeloma (MM) progression. Simultaneously, previous studies showed the possibility of PD-1 and TIM-3 expression on T cells upon stimulation with common γ-chain family cytokines in vitro and during homeostatic proliferation. The aim of the present work was to study the impact of homeostatic proliferation on the expansion of certain T cell subsets up-regulating PD-1 and TIM-3 checkpoint molecules. Methods: The expression of CD25, CD122, CD127 common γ-chain cytokine receptors, phosphorylated signal transducer and activator of transcription-5 (pSTAT5) and eomesodermin (EOMES) was comparatively assessed with flow… More >

Youqi Jiang^1,#, Bing Wu^2,#, Jiahui Chen³, Ruyi Jin³, Guangshan Jin³, Minhao Zhang⁴, Qin Zhou^4,*, Aiji Jiang^2,*

Psycho-Oncologie, Vol.18, No.3, pp. 191-200, 2024, DOI:10.32604/po.2024.053942 - 12 September 2024

Abstract Objective: This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression. Methods: A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital. The survey included demographic information, the Connor–Davidson Resilience Scale (CD-RISC), the Family Resilience Assessment Scale (FRAS), and the Chinese version of the Patient Health Questionnaire-9 (PHQ-9) for Depression. The relationship among individual resilience, family resilience, and depression… More >

Huimin Zheng, Minghui Wang^*, Miao Ye

Psycho-Oncologie, Vol.18, No.3, pp. 169-179, 2024, DOI:10.32604/po.2024.052703 - 12 September 2024

Abstract Background: Although fear of cancer recurrence (FCR) is the most important factor affecting the life quality of young breast cancer patients, and it may be affected by the patient’s personality, marital relationship and communication, there is a lack of research on the relationship between adult attachment, self-disclosure and FCR in patients. This study investigated the current situation of FCR in young breast cancer patients, its correlation with adult attachment and self-disclosure and its influencing factors, in order to predict the impact of adult attachment and self-disclosure of patients to spouse on FCR. Methods: A survey… More >

Qian Liu^1,#, Hui Zhang^1,#, Juan Gao², Meiping Sha¹, Lijun Shen¹, Xianfeng Cheng^3,*, Hao Chen^4,*

Psycho-Oncologie, Vol.18, No.3, pp. 213-221, 2024, DOI:10.32604/po.2024.052607 - 12 September 2024

Abstract Background: Keratinocyte carcinoma (KC) is a common malignancy characterized by a high recurrence rate and considerable psychological distress. The incidence of KC is increasing in China, raising concerns about its psychological consequences and adverse effects on quality of life. Demographic and clinical factors are thought to influence mental health outcomes in these patients. Nonetheless, data on the prevalence of anxiety in Chinese patients with KC and the factors associated with this anxiety are notably lacking. Therefore, a comprehensive investigation into the anxiety of patients with KC is imperative. Objective: This study aimed to investigate the… More >

Nevena Stojadinović¹, Goran Mihajlović¹, Marko Spasić¹, Milena Mladenović¹, Darko Hinić^2,*

Psycho-Oncologie, Vol.18, No.3, pp. 159-168, 2024, DOI:10.32604/po.2024.050122 - 12 September 2024

Abstract Breast cancer is considered one of the most frequent causes of morbidity and death in women. Individuals’ response to information regarding health threats and illness can influence the adjustment of the treatment to existing conditions including the issues of non-completion of treatment or non-attendance at medical appointments. The study aimed to examine the relationship between illness perception, body image dissatisfaction and (mal)adaptive coping styles in breast cancer patients. A sample of 197 patients with diagnosed breast cancer hospitalized at the Center for Oncology and Radiology, Kragujevac, Serbia, was surveyed. The instruments included sociodemographic questionnaire, a… More >

Nada Charfi^1,3,*, Nour Regaieg^1,3, Ines Ayadi^2,3, Najeh Smaoui^1,3, Rim Feki^1,3, Imen Gassara^1,3, Sana Omri^1,3, Lobna Zouari^1,3, Jihène Ben Thabet^1,3, Manel Maâlej Bouali^1,3, Afef Khanfir^2,3, Mohamed Maâlej^1,3

Psycho-Oncologie, Vol.18, No.3, pp. 241-248, 2024, DOI:10.32604/po.2024.049038 - 12 September 2024

Abstract Le diagnostic et la prise en charge du cancer du sein (CS) affectent d’une manière complexe la vie sexuelle des femmes et touchent au symbole de la féminité, qui est très important dans la constitution de l’image du corps. Nos objectifs ont été d’évaluer le fonctionnement sexuel et l’image du corps des patientes en rémission d’un CS localisé, de déterminer les liens entre ces deux paramètres et d’étudier leur rapport avec les modalités thérapeutiques du CS. Nous avons mené une étude transversale, descriptive et analytique au sein des services d’oncologie médicale et de radiothérapie du… More >