Olha Mykhailenko^1,2,3,#,*, Zigmantas Gudžinskas⁴, Liudas Ivanauskas⁵, Victoriya Georgiyants¹, Chia-Hung Yen^6,7,8, Chung-Fan Hsieh⁹, Riong Seulina Panjaitan⁶, Tsong-Long Hwang^10,11,12,13, Bing-Hung Chen^14,15, Michal Korinek^6,7,8,#,*

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074209 - 30 January 2026

Abstract The sustainable sourcing of novel bioactive compounds from natural sources is crucial to the success of the pharmaceutical, food, and cosmetics industries. Iris bucharica Foster (syn. Juno bucharica (Foster) Vved.) is a promising source of novel bioactive molecules, particularly phenolic compounds, which are renowned for their antioxidant properties. In this study, we developed a reliable HPLC-UV-DAD method to identify and quantify phenolic compounds in the leaves and bulbs of I. bucharica, establishing the first set of quality control markers for this species. A total of 21 phenolic compounds were identified in the leaves, with flavonoids isoorientin, guaijaverin, hyperoside, More >

Kai Xie¹, Shaoqing Yuan², Dayun Zou¹, Jinran Wang^1,*, Genjun Chen¹, Ciwei Gao³, Yinghao Cao¹

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.070733 - 27 January 2026

Abstract The construction of spot electricity markets plays a pivotal role in power system reforms, where market clearing systems profoundly influence market efficiency and security. Current clearing systems predominantly adopt a single-system architecture, with research focusing primarily on accelerating solution algorithms through techniques such as high-efficiency parallel solvers and staggered decomposition of mixed-integer programming models. Notably absent are systematic studies evaluating the adaptability of primary-backup clearing systems in contingency scenarios—a critical gap given redundant systems’ expanding applications in operational environments. This paper proposes a comprehensive evaluation framework for analyzing dual-system adaptability, demonstrated through an in-depth case… More >

Mayuri Shukla¹, Soraya Boonmag², Parichart Boontem¹, Piyarat Govitrapong^1,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072557 - 23 January 2026

Abstract Ischemic stroke is one of the major causes of long-term disability and mortality worldwide. It results from an interruption in the cerebral blood flow, triggering a cascade of detrimental events like oxidative stress, mitochondrial dysfunction, neuroinflammation, excitotoxicity, and apoptosis, causing neuronal injury and cellular death. Melatonin, a pleiotropic indoleamine produced by the pineal gland, has multifaceted neuroprotective effects on stroke pathophysiology. Interestingly, the serum melatonin levels are associated with peroxidation and antioxidant status, along with mortality score in patients with severe middle cerebral artery infarction. Melatonin exhibits strong antioxidant, anti-inflammatory, and anti-apoptotic properties and preserves More >

Mariana Francisco¹, Fernando Mendes^1,2,3,4,5,*, Diana Martins^1,2,3,4, Joana Liberal^1,2

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.070276 - 19 January 2026

Abstract Objectives: Colorectal cancer (CRC) is a major global health burden, and Urolithin A (Uro-A) has emerged as a promising anticancer agent. This systematic review aims to synthesize current in vitro evidence on the anticancer effects of Uro-A in CRC, highlighting effective concentration ranges, exposure times, relevant outcomes, and underlying molecular mechanisms. Methods: Following PRISMA 2020 guidelines, a systematic search was conducted in PubMed, Scopus, and Web of Science using the following strategy: (colorectal cancer) AND (urolithin a) OR (3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one). Eligibility criteria were defined by the PICO framework: (P) in vitro CRC cell models; (I) Uro-A alone or… More > Graphic Abstract

Tsu-Yang Wu¹, Chengyuan Yu¹, Yanan Zhao², Saru Kumari³, Chien-Ming Chen^1,*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.069139 - 12 January 2026

Abstract With the increasing complexity of logistics operations, traditional static vehicle routing models are no longer sufficient. In practice, customer demands often arise dynamically, and multi-depot systems are commonly used to improve efficiency. This paper first introduces a vehicle routing problem with the goal of minimizing operating costs in a multi-depot environment with dynamic demand. New customers appear in the delivery process at any time and are periodically optimized according to time slices. Then, we propose a scheduling system TS-DPU based on an improved ant colony algorithm TS-ACO to solve this problem. The classical ant colony More >

Oncology Research Editorial Office

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.077268 - 30 December 2025

Abstract This article has no abstract. More >

Sandra Kałużna^1,*, Monika Świerczewska^1,2, Sylwia Ciesiółka¹, Małgorzata Partyka¹, Michał Nowicki¹, Karolina Wojtowicz¹

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070356 - 30 December 2025

Abstract The last research focuses on the role of exosomes in cancer treatment. Exosomes are extracellular vesicles. They can be secreted by cancer cells, and they can modulate chemotherapy sensitivity. Determining exosomal content opens the possibility for guiding treatment strategies for cancer diseases. Exosomal microRNA are considered one of the prime candidates for exosomal biomarkers. Exosomal circular RNAs represent excellent biomarkers for liquid biopsy because of their stability in many types of cancer. Exosomal proteins remain reliable biomarkers also. Exosomes have emerged as promising therapeutic candidates. Their biological properties render them ideal vectors for drug delivery.… More >

Marija Macenić, Tomislav Kurevija^*, Tin Herbst

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.067067 - 27 December 2025

Abstract The increased interest in geothermal energy is evident, along with the exploitation of traditional hydrothermal systems, in the growing research and projects developing around the reuse of already-drilled oil, gas, and exploration wells. The Republic of Croatia has around 4000 wells, however, due to a long period since most of these wells were drilled and completed, there is uncertainty about how many are available for retrofitting as deep-borehole heat exchangers. Nevertheless, as hydrocarbon production decreases, it is expected that the number of wells available for the revitalization and exploitation of geothermal energy will increase. The… More >

Chang Su, Liangliang Zhao^*, Dongbing Xiang

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-24, 2026, DOI:10.32604/cmc.2025.071319 - 09 December 2025

Abstract To address low learning efficiency and inadequate path safety in spraying robot navigation within complex obstacle-rich environments—with dense, dynamic, unpredictable obstacles challenging conventional methods—this paper proposes a hybrid algorithm integrating Q-learning and improved A*-Artificial Potential Field (A-APF). Centered on the Q-learning framework, the algorithm leverages safety-oriented guidance generated by A-APF and employs a dynamic coordination mechanism that adaptively balances exploration and exploitation. The proposed system comprises four core modules: (1) an environment modeling module that constructs grid-based obstacle maps; (2) an A-APF module that combines heuristic search from A* algorithm with repulsive force strategies from… More >

Fang Liu^*, Xianghui Meng, Jiachen Li, Sibo Guo

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-21, 2026, DOI:10.32604/cmc.2025.069243 - 09 December 2025

Abstract With the popularization of smart devices, Location-Based Services (LBS) greatly facilitates users’ life, but at the same time brings the risk of users’ location privacy leakage. Existing location privacy protection methods are deficient, failing to reasonably allocate the privacy budget for non-outlier location points and ignoring the critical location information that may be contained in the outlier points, leading to decreased data availability and privacy exposure problems. To address these problems, this paper proposes a Mix Location Privacy Preservation Method Based on Differential Privacy with Clustering (MLDP). The method first utilizes the DBSCAN clustering algorithm… More >