Indra Mamad Gandidi^1,2,*, Sukarni Sukarni^3,4, Avita Ayu Permanasari³, Purnami Purnami⁵, Tuan Amran Tuan Abdullah⁶, Anwar Johari⁶, Nugroho Agung Pambudi^7,*

Energy Engineering, Vol.121, No.12, pp. 3635-3648, 2024, DOI:10.32604/ee.2024.054943 - 22 November 2024

Abstract The use of catalysts has significantly enhanced the yield and quality of in-situ pyrolysis products. However, there is a lack of understanding regarding pyrolysis approaches that utilize several low-cost natural catalysts (LCC) and their placement within the reactor. Therefore, this study aims to examine the effects of various LCC on the in-situ pyrolysis of spirulina platensis microalgae (SPM) and investigate the impact of different types of catalysts. We employed LCC such as zeolite, dolomite, kaolin, and activated carbon, with both layered and uniformly mixed LCC-SPM placements. Each experiment was conducted at a constant temperature of 500°C… More > Graphic Abstract

Bo Yang¹, Rui Zhang¹, Jie Zhang², Xianlong Cheng², Jiale Li³, Yimin Zhou¹, Yuanweiji Hu¹, Bin He¹, Gongshuai Zhang⁴, Xiuping Du⁴, Si Ji⁵, Yiyan Sang⁶, Zhengxun Guo^7,8,*

Energy Engineering, Vol.121, No.12, pp. 3487-3547, 2024, DOI:10.32604/ee.2024.054662 - 22 November 2024

Abstract In recent years, the large-scale grid connection of various distributed power sources has made the planning and operation of distribution grids increasingly complex. Consequently, a large number of active distribution network reconfiguration techniques have emerged to reduce system losses, improve system safety, and enhance power quality via switching switches to change the system topology while ensuring the radial structure of the network. While scholars have previously reviewed these methods, they all have obvious shortcomings, such as a lack of systematic integration of methods, vague classification, lack of constructive suggestions for future study, etc. Therefore, this… More >

Mitra Madanchian^1,*, Hamed Taherdoost^1,2,3,4

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2133-2159, 2024, DOI:10.32604/cmc.2024.057094 - 18 November 2024

Abstract This comparative review explores the dynamic and evolving landscape of artificial intelligence (AI)-powered innovations within high-tech research and development (R&D). It delves into both theoretical models and practical applications across a broad range of industries, including biotechnology, automotive, aerospace, and telecommunications. By examining critical advancements in AI algorithms, machine learning, deep learning models, simulations, and predictive analytics, the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies. The review integrates both qualitative and quantitative data derived from academic studies, industry reports, and real-world case studies to showcase the… More >

Alonso Alvarez, Borja Bordel Sánchez^*

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2935-2966, 2024, DOI:10.32604/cmc.2024.056990 - 18 November 2024

Abstract Agile Transformations are challenging processes for organizations that look to extend the benefits of Agile philosophy and methods beyond software engineering. Despite the impact of these transformations on organizations, they have not been extensively studied in academia. We conducted a study grounded in workshops and interviews with 99 participants from 30 organizations, including organizations undergoing transformations (“final organizations”) and companies supporting these processes (“consultants”). The study aims to understand the motivations, objectives, and factors driving and challenging these transformations. Over 700 responses were collected to the question and categorized into 32 objectives. The findings show More >

WEITAO ZHENG¹, DONG JIANG², SONGEN CHEN¹, MEILING WU¹, BAOQI YAN², JIAHUI ZHAI², YUNQIANG SHI², BIN XIE¹, XINGWANG XIE², KANGHONG HU^1,*, WENXUE MA^3,*

Oncology Research, Vol.32, No.12, pp. 1837-1850, 2024, DOI:10.32604/or.2024.056565 - 13 November 2024

Abstract Objectives: The Kirsten rat sarcoma virus (KRAS) G12D oncogenic mutation poses a significant challenge in treating solid tumors due to the lack of specific and effective therapeutic interventions. This study aims to explore innovative approaches in T cell receptor (TCR) engineering and characterization to target the KRAS G12D_7-16 mutation, providing potential strategies for overcoming this therapeutic challenge. Methods: In this innovative study, we engineered and characterized two T cell receptors (TCRs), KDA11-01 and KDA11-02 with high affinity for the KRAS G12D_7-16 mutation. These TCRs were isolated from tumor-infiltrating lymphocytes (TILs) derived from tumor tissues of patients More >

MAHDI ABDOLI SHADBAD¹, BEHZAD BARADARAN^2,*

Oncology Research, Vol.32, No.12, pp. 1949-1958, 2024, DOI:10.32604/or.2024.051569 - 13 November 2024

Abstract Background: Glioblastoma remains a highly invasive primary brain malignancy with an undesirable prognosis. Growing evidence has shed light on the importance of microRNAs (miRs), as small non-coding RNAs, in tumor development and progression. The present study leverages the in-silico and in-vitro techniques to investigate the significance of hsa-miR-181a-5p and the underlying hsa-miR-181a-5p-meidated signaling pathway in glioblastoma development. Methods: Bioinformatic studies were performed on GSE158284, GSE108474 (REMBRANDT study), TCGA-GTEx, CCLE, GeneMANIA, Reactome, WikiPathways, KEGG, miRDB, and microT-CDS to identify the significance of hsa-miR-181a-5p and its underlying target. Afterward, the U373 cell line was selected and transfected with… More >

YUQIN YIN^1,2,#, YU WU^1,#, HONGLIANG HUANG^1,2, YINGYING DUAN^1,2, ZHONGWEN YUAN^1,2, LIHUI CAO^1,2, JINJIN YING^1,2, YONGHENG ZHOU^3,*, SENLING FENG^1,2,*

Oncology Research, Vol.32, No.12, pp. 1891-1902, 2024, DOI:10.32604/or.2024.048778 - 13 November 2024

Abstract Background: Polymethoxylated flavones (PMFs) are compounds present in citrus peels and other Rutaceae plants, which exhibit diverse biological activities, including robust antitumor and antioxidant effects. However, the mechanism of PMFs in reversing drug resistance to colon cancer remains unknown. In the present study, we aimed to investigate the potential connection between the aerobic glycolysis-ROS-autophagy signaling axis and the reversal of PTX resistance in colon cancer by PMFs. Methods: MTT Cell viability assay and colony formation assay were used to investigate the effect of PMFs combined with PTX in reversing HCT8/T cell resistance ex vivo; the mRNA… More > Graphic Abstract

Petrayuna Dian Omega¹, Joniarto Parung^1,*, Listyo Yuwanto¹, Yuh-Shan Ho^2,*

International Journal of Mental Health Promotion, Vol.26, No.10, pp. 817-836, 2024, DOI:10.32604/ijmhp.2024.056501 - 31 October 2024

Abstract Background: This study aimed to conduct a bibliometric analysis of positive mental health, focusing on citation performance, article title, abstract, author keywords, Keyword Plus, and their development trends. The novelty of this study is a pioneer within the field of positive mental health. Therefore, it delivered new ideas for researchers and practitioners who had concerns about positive mental health in terms of trends research which covered recommended articles and the research focus in recent years. Methods: The data were retrieved on 30 April 2024 from the Social Sciences Citation Index (SSCI) of Clarivate Analytics’ Web of… More >

Qianshuo Liu, Jun Zhao^*

Phyton-International Journal of Experimental Botany, Vol.93, No.10, pp. 2663-2681, 2024, DOI:10.32604/phyton.2024.056054 - 30 October 2024

Abstract Traditional machine vision algorithms have difficulty handling the interference of light and shadow changes, broken rows, and weeds in the complex growth circumstances of soybean fields, which leads to erroneous navigation route segmentation. There are additional shortcomings in the feature extractFion capabilities of the conventional U-Net network. Our suggestion is to utilize an improved U-Net-based method to tackle these difficulties. First, we use ResNet’s powerful feature extraction capabilities to replace the original U-Net encoder. To enhance the concentration on characteristics unique to soybeans, we integrate a multi-scale high-performance attention mechanism. Furthermore, to do multi-scale feature… More >

Oncology Research Editorial Office

Oncology Research, Vol.32, No.11, pp. 1817-1817, 2024, DOI:10.32604/or.2024.056892 - 16 October 2024

Abstract This article has no abstract. More >