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  • Open Access

    ARTICLE

    PLDMLT: Multi-Task Learning of Diabetic Retinopathy Using the Pixel-Level Labeled Fundus Images

    Hengyang Liu, Chuncheng Huang*

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1745-1761, 2023, DOI:10.32604/cmc.2023.040710

    Abstract In the field of medical images, pixel-level labels are time-consuming and expensive to acquire, while image-level labels are relatively easier to obtain. Therefore, it makes sense to learn more information (knowledge) from a small number of hard-to-get pixel-level annotated images to apply to different tasks to maximize their usefulness and save time and training costs. In this paper, using Pixel-Level Labeled Images for Multi-Task Learning (PLDMLT), we focus on grading the severity of fundus images for Diabetic Retinopathy (DR). This is because, for the segmentation task, there is a finely labeled mask, while the severity grading task is without classification… More >

  • Open Access

    CASE REPORT

    Compound Heterozygous PLD1 Variants in Right-Sided Heart Malformations

    Cherith Somerville1,2, Kelsey Kalbfleisch1,2, Roozbeh Manshaei1,2, Qiliang Ding1,2, John B.A. Okello1,2,3, Rachel Silver4, David Chitayat2,4, Varsha Thakur5, Olivier Villemain5,6,7, Rebekah Jobling1,2,8,*

    Congenital Heart Disease, Vol.18, No.2, pp. 213-218, 2023, DOI:10.32604/chd.2023.023042

    Abstract We report a three-year-old male child who presented with congenital valvular defects, right ventricular malformation, and initial developmental delay. Genome sequencing showed rare deleterious biallelic missense variants in PLD1. In his parents’ second pregnancy, echocardiogram at 13 weeks gestation revealed right-sided cardiac malformations resembling the clinical presentation of the family’s first child. Targeted DNA analysis showed that the fetus carried the same biallelic PLD1 variants as their older sibling. This case helps to further delineate the clinical spectrum of PLD1-related defects and highlights the value of both genome sequencing in congenital heart disease and early fetal echocardiography to establish phenotype. More >

  • Open Access

    ARTICLE

    Physical Properties of SiC Nanostructure for Optoelectronics Applications

    Mayyadah H. Mohsin1, Najwan H. Numan2, Evan T. Salim1,*, Makram A. Fakhri2,*

    Journal of Renewable Materials, Vol.9, No.9, pp. 1519-1530, 2021, DOI:10.32604/jrm.2021.015465

    Abstract A SiC nanofilms have been deposited and investigated on quartz and silicon substrates using pulsed laser deposition technique with the 300 pulses of Nd: YAG laser at two different laser wavelengths of 1064 nm and 532 nm. The structural, morphological, and optical properties of the deposited nanostructure SiC were prepared and characterized as a function of the wavelengths of the used laser. The structural result shows four different pecks at (111), (200), (220), and (311) planes related to Nano SiC. The transmission result presents that the optical energy gap value for the SiC nanostructure is depended on the wavelength of… More > Graphic Abstract

    Physical Properties of SiC Nanostructure for Optoelectronics Applications

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