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  • Open Access

    ARTICLE

    Classification of Multi-view Digital Mammogram Images Using SMO-WkNN

    P. Malathi1,*, G. Charlyn Pushpa Latha2

    Computer Systems Science and Engineering, Vol.46, No.2, pp. 1741-1758, 2023, DOI:10.32604/csse.2023.035185

    Abstract Breast cancer (BCa) is a leading cause of death in the female population across the globe. Approximately 2.3 million new BCa cases are recorded globally in females, overtaking lung cancer as the most prevalent form of cancer to be diagnosed. However, the mortality rates for cervical and BCa are significantly higher in developing nations than in developed countries. Early diagnosis is the only option to minimize the risks of BCa. Deep learning (DL)-based models have performed well in image processing in recent years, particularly convolutional neural network (CNN). Hence, this research proposes a DL-based CNN model to diagnose BCa from… More >

  • Open Access

    ARTICLE

    MicroRNA-1277 Inhibits Proliferation and Migration of Hepatocellular Carcinoma HepG2 Cells by Targeting and Suppressing BMP4 Expression and Reflects the Significant Indicative Role in Hepatocellular Carcinoma Pathology and Diagnosis After Magnetic Resonance Imaging Assessment

    Xinshan Cao*, Ling Xu, Quanyuan Liu*, Lijuan Yang, Na Li§, Xiaoxiao Li*

    Oncology Research, Vol.27, No.3, pp. 301-309, 2019, DOI:10.3727/096504018X15213058045841

    Abstract Our study aimed to investigate the roles and possible regulatory mechanism of miR-1277 in the development of hepatocellular carcinoma (HCC). HCC patients were identified from patients who were diagnosed with focal liver lesions using magnetic resonance imaging (MRI). The expression levels of miR-1277 in the serum of HCC patients and HepG2 cells were measured. Then miR-1277 mimic, miR-1277 inhibitor, or scramble RNA was transfected into HepG2 cells. The effects of miR-1277 overexpression and suppression on HepG2 cell proliferation, migration, and invasion were then investigated. Additionally, the expression levels of epithelial– mesenchymal transition (EMT)-related markers, including E-cadherin, -catenin, and vimentin, were… More >

  • Open Access

    ARTICLE

    Transplantation of BMP-7 gene-transfected bone marrow mesenchymal stem cells for the treatment of spinal cord injury in rats

    XUYI WANG1, WEN ZHANG2, LEI GAO2, KUANXIN LI1,3,*

    BIOCELL, Vol.46, No.9, pp. 2065-2072, 2022, DOI:10.32604/biocell.2022.018265

    Abstract Background: Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, and there is currently no effective treatment for SCI because of its complicated pathophysiology. Bone marrow mesenchymal stem cells (BMSCs) have multidirectional differentiation abilities. Our study aims to explore the effects of bone morphogenetic protein 7 (BMP-7)-modified BMSCs transplantation on the repair of SCI in rats. Methods: In this study, a rat spinal cord injury model was established with the modified Allen method. Then, BMSCs transfected with the BMP7 gene were transplanted to treat the spinal cord injury in rats. Forty Sprague-Dawley rats were randomly… More >

  • Open Access

    ARTICLE

    Development and Field Application of Phosphogypsum-Based Soil Subgrade Stabilizers

    Hongfei Yue1, Aiguo Fang2, Sudong Hua1,*, Zenghuan Gu3, Yu Jia1, Cheng Yang4

    Journal of Renewable Materials, Vol.10, No.8, pp. 2247-2261, 2022, DOI:10.32604/jrm.2022.018901

    Abstract A phosphogypsum-based subgrade stabilizer (PBSS) was formulated using industrial by-product phosphogypsum (PG), mixed with slag and calcium-silicon-rich active material (GSR). The active powder (AP) was used to modify PBSS, and PBSS-AP was obtained. PBSS and PBSS-AP were each mixed with 10% silty soil, and cement and lime (CAL: 5% lime + 2% cement) were used as the traditional material for comparative experiments. Samples were cured under standard conditions, and tested for unconfined compressive strength (UCS), water stability, volume expansion, and leachate, to explore the stabilization effect of the three solidified materials on silty soil. The results showed that the comprehensive… More >

  • Open Access

    ARTICLE

    Ground Nephogram Enhancement Algorithm Based on Improved Adaptive Fractional Differentiation

    Xiaoying Chen1,*, Jie Kang1, Cong Hu2

    Journal of New Media, Vol.3, No.4, pp. 151-180, 2021, DOI:10.32604/jnm.2021.024665

    Abstract The texture of ground-based nephogram is abundant and multiplicity. Many cloud textures are not as clear as artificial textures. A nephogram enhancement algorithm based on Adaptive Fractional Differential is established to extract the natural texture of visible ground-based cloud image. GrunwaldLentikov (G-L) and Grunwald-Lentikov (R-L) fractional differential operators are applied to the enhancement algorithm of ground-based nephogram. An operator mask based on adaptive differential order is designed. The corresponding mask template is used to process each pixel. The results show that this method can extract image texture and edge details and simplify the process of differential order selection. More >

  • Open Access

    ARTICLE

    Study on Performance Regulation and Mechanism of Quicklime and Biopolymer on Hemihydrate Phosphogypsum

    Zaibo Zhou1, Juanhong Liu1,2,3,*, Kun Luo1, Aixiang Wu1,3, Hongjiang Wang1,3

    Journal of Renewable Materials, Vol.10, No.2, pp. 373-384, 2022, DOI:10.32604/jrm.2022.016380

    Abstract In order to reduce the influence of impurities in hemihydrate phosphogypsum(HPG) on the environment and improve the workability of HPG, the effects of the content of quicklime and types of biopolymer (hydroxypropyl methylcellulose, xanthan gum, sodium polyacrylate(PAANa)) on the compressive strength, softening coefficient and ultrasonic velocity of HPG were evaluated. When the content of quicklime was 1.5% and the content of PAANa was 0.2%, HPG had the best mechanical properties and workability, its water retention rate can be increased by 5.8%, and unconfined compressive strength of 3 days increased by 10.3% and 7 days increased by 13.1%. Through the analysis… More > Graphic Abstract

    Study on Performance Regulation and Mechanism of Quicklime and Biopolymer on Hemihydrate Phosphogypsum

  • Open Access

    ARTICLE

    AFP2 Coordinates the Activity of PIF7 for Thermomorphogenesis in Arabidopsis Seedlings

    Guoli Deng, Songbei Ying, Sasa Jing, Jun Zhou, Shiyan Lu, Ping Li*

    Phyton-International Journal of Experimental Botany, Vol.90, No.4, pp. 1089-1101, 2021, DOI:10.32604/phyton.2021.016217

    Abstract Ambient temperature induces the hypocotyl elongation of seedling, called as thermomorphogenesis. It has been reported that the bHLH transcriptional factor PIF7 acts as the critical component to modulate plant thermomorphogenesis, but the underlying mechanism remains elusive. The phytohormone abscisic acid (ABA) suppresses the hypocotyl elongation under high temperature (HT) stress. As the ABI5 binding protein, AFP2 acts as the negative factor to control ABA signaling. In this study, we first identified AFP2 as the interaction protein of PIF7 in vitro and in vivo. Phenotype analysis revealed that overexpressing AFP2 reduced the hypocotyl elongation, while loss-of-function afp2 mutant showed longer hypocotyl… More >

  • Open Access

    ARTICLE

    Development of a Soil Stabilizer for Road Subgrade Based on Original Phosphogypsum

    Zenghuan Gu1, Aiguo Fang2, Sudong Hua1,*, Qingzhou Zhao2, Lidong Sun2, Fan Xia2, Liying Qian3, Xiaojian Ren3

    Journal of Renewable Materials, Vol.9, No.2, pp. 253-268, 2021, DOI:10.32604/jrm.2021.011912

    Abstract The research used industrial by-products original phosphogypsum (PG) as the main raw material, slag (SG) and Portland cement (PC) as auxiliary materials, and the optimal additive amount was determined according to the compressive strength value of the sample. Comprehensively evaluate the water resistance and volume stability of the samples, and determine the best formula for new roadbed stabilized materials. The results showed that when the weight ratio of PG, slag and cement was OPG:SG:PC = 6:3:1, and mixed with 5% micro silica fume (MSF) and 3‰ hydroxypropyl methyl cellulose (HPMC), the sample’s comprehensive performance was the best, specifically, the sample’s… More >

  • Open Access

    ARTICLE

    Utilization of Bayer Red Mud Derived from Bauxite for Belite-Ferroaluminate Cement Production

    Yanrong Zhao1,2,3,#, Ping Chen1,4,*,#, Shifeng Wang5, Yaxiong Ji3,4, Yuanhao Wang3,4,*, Bolin Wu1,2, Rongjin Liu1

    Journal of Renewable Materials, Vol.8, No.11, pp. 1531-1541, 2020, DOI:10.32604/jrm.2020.011462

    Abstract Bayer red mud (BRM) is a kind of industrial solid waste characterized by huge volume and high alkalinity. Its disposal generates serious environmental pollution and occupies a large number of farmland. The utilization and recycling of BRM is currently a crucial issue and needs to be addressed as soon as possible. The chemical composition of BRM is similar to cement clinker. In this study, the feasibility of preparing Belite-ferroaluminate clinker (BFAC) with different BRM was explored. The physical properties, mechanics performance, radioactivity levels and trace harmful metals leaching were measured. XRD, BEI and EDS were used to characterize the mineral… More >

  • Open Access

    ARTICLE

    Effects of Different Spectra from LED on the Growth, Development and Reproduction of Arabidopsis thaliana

    Tengyue Zou, Bing Wu, Wen Wu, Long Ge, Yong Xu*

    Phyton-International Journal of Experimental Botany, Vol.89, No.2, pp. 275-289, 2020, DOI:10.32604/phyton.2020.09277

    Abstract Light is the major source of energy for plants and as such has a profound effect on plant growth and development. Red and blue lights have been considered to best drive photosynthetic metabolism and are beneficial for plant growth and development, and green light was seen as a signal to slow down or stop. In this study, Arabidopsis thaliana (Arabidopsis) was used to investigate the effects of red, blue and green lights on the growth and development of plants from seed germination to seeding. Results demonstrated that red light showed a promotion effect but blue light a prohibition one in… More >

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