Hexin Yue1, Cian Vyas1,2,*, Paulo Bartolo1,2,*
The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011598
Abstract Peripheral nerve injury can result in significant motor or sensory impairment. Traditional treatments have certain drawbacks and often result in suboptimal clinical results. To overcome these limitations, tissue engineering and bioprinting technologies are promising approaches for manufacturing nerve guidance conduits (NGCs). NGCs are tubular biostructures that bridge the nerve injury site, provide an appropriate microenvironment, and promote peripheral nerve regeneration by guiding axonal growth. The architecture of NGCs needs to mimic the morphology of natural peripheral nerves by designing their topology to regulate nerve cell behaviours. Topographic guidance cues are an effective element in improving… More >
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