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  • Open Access

    ARTICLE

    LncRNA PCGEM1 facilitates cervical cancer progression via miR-642a-5p/KIF5B axis

    YUANLIN LIU1,3,#, YAN LIU2,#, YAN WANG2, QIANG WANG2, YAN YAN1, DANDAN ZHANG2,*, HUIQIN LIU2,*

    Oncology Research, Vol.32, No.7, pp. 1221-1229, 2024, DOI:10.32604/or.2024.047454

    Abstract At present, the role of many long non-coding RNAs (lncRNAs) as tumor suppressors in the formation and development of cervical cancer (CC) has been studied. However, lncRNA prostate cancer gene expression marker 1 (PCGEM1), whose high expression not only aggravates ovarian cancer but also can induce tumorigenesis and endometrial cancer progression, has not been studied in CC. The objective of this study was to investigate the expression and the underlying role of PCGEM1 in CC. The relative expression of PCGEM1 in CC cells was detected by real-time PCR. After the suppression of PCGEM1 expression by… More > Graphic Abstract

    LncRNA PCGEM1 facilitates cervical cancer progression via miR-642a-5p/KIF5B axis

  • Open Access

    ARTICLE

    Artificial Intelligence in Medicine: Real Time Electronic Stethoscope for Heart Diseases Detection

    Batyrkhan Omarov1,2,*, Nurbek Saparkhojayev2, Shyrynkyz Shekerbekova3, Oxana Akhmetova1, Meruert Sakypbekova1, Guldina Kamalova3, Zhanna Alimzhanova1, Lyailya Tukenova3, Zhadyra Akanova4

    CMC-Computers, Materials & Continua, Vol.70, No.2, pp. 2815-2833, 2022, DOI:10.32604/cmc.2022.019246

    Abstract Diseases of the cardiovascular system are one of the major causes of death worldwide. These diseases could be quickly detected by changes in the sound created by the action of the heart. This dynamic auscultations need extensive professional knowledge and emphasis on listening skills. There is also an unmet requirement for a compact cardiac condition early warning device. In this paper, we propose a prototype of a digital stethoscopic system for the diagnosis of cardiac abnormalities in real time using machine learning methods. This system consists of three subsystems that interact with each other (1)… More >

  • Open Access

    ARTICLE

    Transfer Learning Model to Indicate Heart Health Status Using Phonocardiogram

    Vinay Arora1, Karun Verma1, Rohan Singh Leekha2, Kyungroul Lee3, Chang Choi4,*, Takshi Gupta5, Kashish Bhatia6

    CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 4151-4168, 2021, DOI:10.32604/cmc.2021.019178

    Abstract The early diagnosis of pre-existing coronary disorders helps to control complications such as pulmonary hypertension, irregular cardiac functioning, and heart failure. Machine-based learning of heart sound is an {efficient} technology which can help minimize the workload of manual auscultation by automatically identifying irregular cardiac sounds. Phonocardiogram (PCG) and electrocardiogram (ECG) waveforms provide the much-needed information for the diagnosis of these diseases. In this work, the researchers have converted the heart sound signal into its corresponding repeating pattern-based spectrogram. PhysioNet 2016 and PASCAL 2011 have been taken as the benchmark datasets to perform experimentation. The existing More >

  • Open Access

    ARTICLE

    Study on the Preparation and Adsorption Property of Polyvinyl Alcohol/Cellulose Nanocrystal/Graphene Composite Aerogels (PCGAs)

    Yan Wu1,*, Xinyu Wu1, Feng Yang2,*, Li Xu1, Meng Sun1

    Journal of Renewable Materials, Vol.7, No.11, pp. 1181-1195, 2019, DOI:10.32604/jrm.2019.07493

    Abstract The cellulose nanocrystals/graphene composite aerogel (CGA) and polyvinyl alcohol/cellulose nanocrystals/graphene composite aerogel (PCGA) were prepared by suspension titration, tert-butanol solution replacement and freeze-drying successively. The removal rates of methyl blue (MB) from water by CGA and PCGA were evaluated and the effects of additions, adsorption time, reaction temperature and pH value of CGA and PCGA on MB removal rate were discussed. It was found that the optimal concentrations of both CGA and PCGA were 2 g∙L-1 in the adsorption reaction process and the adsorption equilibrium was reached within 120 min. The higher the initial pH More >

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