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  • Open Access

    REVIEW

    Pioneering a new era in Parkinson’s disease management through adipose-derived mesenchymal stem cell therapy

    MOHAMMAD-SADEGH LOTFI, FATEMEH B. RASSOULI*

    BIOCELL, Vol.48, No.10, pp. 1419-1428, 2024, DOI:10.32604/biocell.2024.053597 - 02 October 2024

    Abstract Parkinson’s disease (PD) is one of the fastest-growing neurodegenerative disorders worldwide. So far, PD treatments only offer little clinical relief and cannot reverse or stop the disease progression. Stem cell (SC) therapy is a rapidly evolving technology that holds significant promise for enhancing current therapeutic approaches. Adipose-derived mesenchymal SCs (AD-MSCs) have many features such as easy harvest with minimal invasive techniques, high plasticity, non-immunogenicity, and no ethical issues, which have made them suitable choices for clinical applications in regenerative research. AD-MSCs are ideal tools to treat PD, as they have the potential to differentiate into… More >

  • Open Access

    ARTICLE

    A Hierarchical Two-Level Feature Fusion Approach for SMS Spam Filtering

    Hussein Alaa Al-Kabbi1,2, Mohammad-Reza Feizi-Derakhshi1,*, Saeed Pashazadeh3

    Intelligent Automation & Soft Computing, Vol.39, No.4, pp. 665-682, 2024, DOI:10.32604/iasc.2024.050452 - 06 September 2024

    Abstract SMS spam poses a significant challenge to maintaining user privacy and security. Recently, spammers have employed fraudulent writing styles to bypass spam detection systems. This paper introduces a novel two-level detection system that utilizes deep learning techniques for effective spam identification to address the challenge of sophisticated SMS spam. The system comprises five steps, beginning with the preprocessing of SMS data. RoBERTa word embedding is then applied to convert text into a numerical format for deep learning analysis. Feature extraction is performed using a Convolutional Neural Network (CNN) for word-level analysis and a Bidirectional Long… More >

  • Open Access

    ARTICLE

    Grasslands Response to Livestock Grazing Intensity in the Austral Pampas (Argentina): Testing the Intermediate Disturbance Hypothesis

    Ana Elena de Villalobos1,2,*, María Andrea Long1,2

    Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 2037-2050, 2024, DOI:10.32604/phyton.2024.053928 - 30 August 2024

    Abstract Livestock grazing has a significant impact on natural grasslands, with approximately one-third of the world’s land area dedicated to this industry. Around 20% of global grasslands are highly degraded due to overgrazing, affecting their productivity and conservation capacity. Best practices are required to ensure sustainable livestock production that supports biodiversity. The Intermediate Disturbance Hypothesis (IDH) suggests that environments with moderate levels of disturbance exhibit a higher species diversity. Moderate grazing can reduce the dominance of certain species, thereby enhancing plant diversity. However, concerns arise regarding the increase of exotic and unpalatable species under moderate grazing… More >

  • Open Access

    ARTICLE

    The Effect of Water and Salt Stress on Paspalum dilatatum, a Constituent of Pampas Natural Grasslands

    Claudia A. Porcelli1, Gerardo Rubio2, Flavio H. Gutiérrez Boem2, Raul S. Lavado2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 2009-2018, 2024, DOI:10.32604/phyton.2024.052874 - 30 August 2024

    Abstract The effects of the salt stress on plant growth are usually increased by the water stress. We studied the impact of both stresses in simultaneous pulses of drought and salinity on Paspalum dilatatum. This forage species is native to South America, spread in grasslands in many tropical, subtropical, and temperate areas of the world, and very common in grasslands of the Flooding Pampas of Argentina. Mimicking what happens in nature. We compared a pot experiment, a non-stressed control against water stress for a month (midpoint between field capacity and wilting point), and two saline stresses (moderate,… More >

  • Open Access

    REVIEW

    Ecosystem Services of Grazed Grasslands in the Flooding Pampa

    Elizabeth J. Jacobo1,#,*, Adriana M. Rodríguez2,#

    Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1179-1202, 2024, DOI:10.32604/phyton.2024.050928 - 27 June 2024

    Abstract The Flooding Pampa grasslands are the last remnant of the Rio de la Plata grasslands in Argentina. Anthropogenic interventions have led to severe degradation and, as a result, the ecosystem services provided by the grasslands are declining, in terms of provisioning, regulating, and supporting services. We synthesized the existing literature on the ecosystem goods and services provided by these grasslands under grazing in different conditions and conservation status. We found that plant and animal diversity and primary production are the most studied ecosystem services, while climate regulation, water supply, nutrient cycling, meat production and erosion… More >

  • Open Access

    REVIEW

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

    VIRAAJ VISHNU PRASAD, JENNIFER SALLY SAMSON, VENKATACHALAM DEEPA PARVATHI*

    BIOCELL, Vol.48, No.5, pp. 693-706, 2024, DOI:10.32604/biocell.2024.048776 - 06 May 2024

    Abstract Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an individual. In addition to aiding the regulation of aerobic and anaerobic metabolism, exercise can stimulate the synthesis of exerkine hormones in the circulatory system. Among several exerkines that have been investigated for their therapeutic potential, Brain-derived neurotrophic factor (BDNF) is considered the most promising candidate, especially in the management of neurodegenerative diseases. Owing to the ability of physical activity to enhance BDNF synthesis, several experimental studies conducted so far have validated this hypothesis and produced satisfactory results at More > Graphic Abstract

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

  • Open Access

    ARTICLE

    CoS Nanosheets Coated with Dopamine-Derived Carbon Standing on Carbon Fiber Cloth as Binder-Free Anode for Li-ion Batteries

    Lianyuan Ji1, Mingchen Shi1, Zengkai Feng2, Hui Yang1,*

    Journal of Renewable Materials, Vol.12, No.2, pp. 259-274, 2024, DOI:10.32604/jrm.2023.030599 - 11 March 2024

    Abstract

    Cobalt sulphides attract much attention as anode materials for Li-ion batteries (LIBs). However, its poor conductivity, low initial column efficiency and large volume changes during cycling have hindered its further development. Herein, novel interlaced CoS nanosheets were firstly prepared on Carbon Fiber Cloth (CFC) by two hydrothermal reactions followed with carbon coating via carbonizing dopamine (CoS NS@C/CFC). As a freestanding anode, the nanosheet structure of CoS not only accommodates the volume variation, but also provides a large interface area to proceed the charge transfer reaction. In addition, CFC works as both a three-dimensional skeleton and an

    More >

  • Open Access

    ARTICLE

    Examining the Use of Scott’s Formula and Link Expiration Time Metric for Vehicular Clustering

    Fady Samann1,2,*, Shavan Askar3

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2421-2444, 2024, DOI:10.32604/cmes.2023.031265 - 15 December 2023

    Abstract Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms. K-clustering algorithms are simplistic, with fast performance and relative accuracy. However, their implementation depends on the initial selection of clusters number (K), the initial clusters’ centers, and the clustering metric. This paper investigated using Scott’s histogram formula to estimate the K number and the Link Expiration Time (LET) as a clustering metric. Realistic traffic flows were considered for three maps, namely Highway, Traffic Light junction, and Roundabout junction, to study the… More >

  • Open Access

    ARTICLE

    Real-Time Spammers Detection Based on Metadata Features with Machine Learning

    Adnan Ali1, Jinlong Li1, Huanhuan Chen1, Uzair Aslam Bhatti2, Asad Khan3,*

    Intelligent Automation & Soft Computing, Vol.38, No.3, pp. 241-258, 2023, DOI:10.32604/iasc.2023.041645 - 27 February 2024

    Abstract Spammer detection is to identify and block malicious activities performing users. Such users should be identified and terminated from social media to keep the social media process organic and to maintain the integrity of online social spaces. Previous research aimed to find spammers based on hybrid approaches of graph mining, posted content, and metadata, using small and manually labeled datasets. However, such hybrid approaches are unscalable, not robust, particular dataset dependent, and require numerous parameters, complex graphs, and natural language processing (NLP) resources to make decisions, which makes spammer detection impractical for real-time detection. For… More >

  • Open Access

    ARTICLE

    Flag-Based Vehicular Clustering Scheme for Vehicular Ad-Hoc Networks

    Fady Samann1,*, Shavan Askar2

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2715-2734, 2023, DOI:10.32604/cmc.2023.043580 - 26 December 2023

    Abstract Clustering schemes in vehicular networks organize vehicles into logical groups. They are vital for improving network performance, accessing the medium, and enabling efficient data dissemination. Most schemes rely on periodically broadcast hello messages to provide up-to-date information about the vehicles. However, the periodic exchange of messages overwhelms the system and reduces efficiency. This paper proposes the Flag-based Vehicular Clustering (FVC) scheme. The scheme leverages a combination of Fitness Score (FS), Link Expiration Time (LET), and clustering status flags to enable efficient cluster formation in a hybrid manner. The FVC relies on the periodic broadcast of… More >

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