Hang Sun, Changsheng Li^*, He Zhang

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2505-2522, 2024, DOI:10.32604/cmc.2024.049898 - 15 May 2024

Abstract Brain–computer interface (BCI) systems, such as the P300 speller, enable patients to express intentions without necessitating extensive training. However, the complexity of operational instructions and the slow pace of character spelling pose challenges for some patients. In this paper, an image segmentation P300 selector based on YOLOv7-mask and DeepSORT is proposed. The proposed system utilizes a camera to capture real-world objects for classification and tracking. By applying predefined stimulation rules and object-specific masks, the proposed system triggers stimuli associated with the objects displayed on the screen, inducing the generation of P300 signals in the patient’s… More >

WEN GE^1,2,#, YA LI^1,2,#, YUTING RUAN^1,2, NINGXIA WU^1,2, PEI MA^3,4, TONGPENG XU^3,4, YONGQIAN SHU^3,4, YINGWEI WANG^1,2, WEN QIU^1,2, CHENHUI ZHAO^3,4,*

Oncology Research, Vol.32, No.4, pp. 625-641, 2024, DOI:10.32604/or.2023.031053 - 20 March 2024

Abstract The cancer cell metastasis is a major death reason for patients with non-small cell lung cancer (NSCLC). Although researchers have disclosed that interleukin 17 (IL-17) can increase matrix metalloproteinases (MMPs) induction causing NSCLC cell metastasis, the underlying mechanism remains unclear. In the study, we found that IL-17 receptor A (IL-17RA), p300, p-STAT3, Ack-STAT3, and MMP19 were up-regulated both in NSCLC tissues and NSCLC cells stimulated with IL-17. p300, STAT3 and MMP19 overexpression or knockdown could raise or reduce IL-17-induced p-STAT3, Ack-STAT3 and MMP19 level as well as the cell migration and invasion. Mechanism investigation revealed… More > Graphic Abstract

A. Benabid Najjar^1,*, N. AlSahly², R. AlShamass¹, M. Hosny²

CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 1169-1189, 2021, DOI:10.32604/cmc.2021.014140 - 12 January 2021

Abstract Technology has tremendously contributed to improving communication and facilitating daily activities. Brain-Computer Interface (BCI) study particularly emerged from the need to serve people with disabilities such as Amyotrophic Lateral Sclerosis (ALS). However, with the advancements in cost-effective electronics and computer interface equipment, the BCI study is flourishing, and the exploration of BCI applications for people without disabilities, to enhance normal functioning, is increasing. Particularly, the P300-based spellers are among the most promising applications of the BCI technology. In this context, the region-based paradigm for P300 BCI spellers was introduced in an effort to reduce the… More >