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  • Open Access

    RETRACTION

    Retraction: Knockdown of Gab1 Inhibits Cellular Proliferation, Migration, and Invasion in Human Oral Squamous Carcinoma Cells

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.8, pp. 1387-1387, 2024, DOI:10.32604/or.2024.055039

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Tmem39b promotes tumor progression and sorafenib resistance by inhibiting ferroptosis in hepatocellular carcinoma

    MING ZHUANG, XUE ZHANG, LU LI, LIMING WEN, JIAMIN QIN*

    Oncology Research, Vol.32, No.8, pp. 1347-1357, 2024, DOI:10.32604/or.2024.046170

    Abstract Hepatocellular carcinoma (HCC) poses a significant threat to human health. Resistance to sorafenib in the chemotherapy of HCC is a common and significant issue that profoundly impacts clinical treatment. While several members of the transmembrane (TMEM) protein family have been implicated in the occurrence and progression of HCC, the association between TMEM39b and HCC remains unexplored. This study revealed a significant overexpression of TMEM39b in HCC, which correlated with a poor prognosis. Subsequent investigation revealed that RAS-selective lethal 3 (RSL3) induced pronounced ferroptosis in HCC, and knocking down the expression of TMEM39b significantly decreased its More >

  • Open Access

    REVIEW

    Biometric Authentication System on Mobile Environment: A Review

    Qasem Abu Al-Haija1,*, Sara Othman Al-Salameen2

    Computer Systems Science and Engineering, Vol.48, No.4, pp. 897-914, 2024, DOI:10.32604/csse.2024.050846

    Abstract The paper discusses the importance of biometric verification systems in mobile environments and highlights the challenges and strategies used to overcome them in order to ensure the security of mobile devices. Emphasis is placed on evaluating the impact of illumination on the performance of biometric verification techniques and how to address this challenge using image processing techniques. The importance of accurate and reliable data collection to ensure the accuracy of verification processes is also discussed. The paper also highlights the importance of improving biometric verification techniques and directing research toward developing models aimed at reducing More >

  • Open Access

    ARTICLE

    Multi-Scale Location Attention Model for Spatio-Temporal Prediction of Disease Incidence

    Youshen Jiang1, Tongqing Zhou1, Zhilin Wang2, Zhiping Cai1,*, Qiang Ni3

    Intelligent Automation & Soft Computing, Vol.39, No.3, pp. 585-597, 2024, DOI:10.32604/iasc.2023.030221

    Abstract Due to the increasingly severe challenges brought by various epidemic diseases, people urgently need intelligent outbreak trend prediction. Predicting disease onset is very important to assist decision-making. Most of the existing work fails to make full use of the temporal and spatial characteristics of epidemics, and also relies on multivariate data for prediction. In this paper, we propose a Multi-Scale Location Attention Graph Neural Networks (MSLAGNN) based on a large number of Centers for Disease Control and Prevention (CDC) patient electronic medical records research sequence source data sets. In order to understand the geography and… More >

  • Open Access

    ARTICLE

    Experiments and Analyses on Heat Transfer Characteristics from a Solid Wall to a Strip-Shaped Wick Structure

    Kenta Hashimoto1, Guohui Sun1, Yasushi Koito2,*

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 687-702, 2024, DOI:10.32604/fhmt.2024.052928

    Abstract Centered or striped wick structures have been used to develop ultrathin heat pipes. Differing from traditional heat pipes, the centered or striped wick structures leave noncontact container surfaces with the wick structure. In this study, experiments and numerical analyses were conducted to investigate the influence of these noncontact surfaces. In the experiments, a strip-shaped wick structure was placed vertically, the top was sandwiched between wider rods and the bottom was immersed in a working fluid. The rod width was greater than the wick width; thus, noncontact surfaces were left between the rod and the wick… More >

  • Open Access

    ARTICLE

    Experimental Study on Improving Performance and Productivity of Pyramid Solar Still Using Rotation Technique

    Ali Abdullah Abbas Baiee, Sasan Asiaei*, Sayed Mostafa Hosseinalipour*

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 955-976, 2024, DOI:10.32604/fhmt.2024.051532

    Abstract Globally, potable water scarcity is pervasive problem. The solar distillation device is a straightforward apparatus that has been purposefully engineered to convert non-potable water into potable water. The experimental study is distinctive due to the implementation of a rotational mechanism within the pyramidal solar still (PSS), which serves to enhance the evaporation and condensation processes. The objective of this research study is to examine the impact of integrating rotational motion into pyramidal solar stills on various processes: water distillation, evaporation, condensation, heat transfer, and energy waste reduction, shadow effects, and low water temperature in saline… More >

  • Open Access

    ARTICLE

    In-Depth Study of Potential-Based Routing and New Exploration of Its Scheduling Integration

    Jihoon Sung1, Yeunwoong Kyung2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2891-2911, 2024, DOI:10.32604/cmes.2024.051772

    Abstract Industrial wireless mesh networks (WMNs) have been widely deployed in various industrial sectors, providing services such as manufacturing process monitoring, equipment control, and sensor data collection. A notable characteristic of industrial WMNs is their distinct traffic pattern, where the majority of traffic flows originate from mesh nodes and are directed towards mesh gateways. In this context, this paper adopts and revisits a routing algorithm known as ALFA (autonomous load-balancing field-based anycast routing), tailored specifically for anycast (one-to-one-of-many) networking in WMNs, where traffic flows can be served through any one of multiple gateways. In essence, the… More >

  • Open Access

    REVIEW

    A Comprehensive Systematic Review: Advancements in Skin Cancer Classification and Segmentation Using the ISIC Dataset

    Madiha Hameed1,3, Aneela Zameer1,*, Muhammad Asif Zahoor Raja2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2131-2164, 2024, DOI:10.32604/cmes.2024.050124

    Abstract The International Skin Imaging Collaboration (ISIC) datasets are pivotal resources for researchers in machine learning for medical image analysis, especially in skin cancer detection. These datasets contain tens of thousands of dermoscopic photographs, each accompanied by gold-standard lesion diagnosis metadata. Annual challenges associated with ISIC datasets have spurred significant advancements, with research papers reporting metrics surpassing those of human experts. Skin cancers are categorized into melanoma and non-melanoma types, with melanoma posing a greater threat due to its rapid potential for metastasis if left untreated. This paper aims to address challenges in skin cancer detection… More >

  • Open Access

    ARTICLE

    Efficient Penetration Testing Path Planning Based on Reinforcement Learning with Episodic Memory

    Ziqiao Zhou1, Tianyang Zhou1,*, Jinghao Xu2, Junhu Zhu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2613-2634, 2024, DOI:10.32604/cmes.2023.028553

    Abstract Intelligent penetration testing is of great significance for the improvement of the security of information systems, and the critical issue is the planning of penetration test paths. In view of the difficulty for attackers to obtain complete network information in realistic network scenarios, Reinforcement Learning (RL) is a promising solution to discover the optimal penetration path under incomplete information about the target network. Existing RL-based methods are challenged by the sizeable discrete action space, which leads to difficulties in the convergence. Moreover, most methods still rely on experts’ knowledge. To address these issues, this paper… More >

  • Open Access

    ARTICLE

    Paclitaxel induces human KOSC3 oral cancer cell apoptosis through caspase pathways

    YU-YAN LAN1,#, TSUN-CHIH CHENG2,#, YI-PING LEE3, CHIA-YIH WANG3,*, BU-MIIN HUANG3,4,*

    BIOCELL, Vol.48, No.7, pp. 1047-1054, 2024, DOI:10.32604/biocell.2024.050701

    Abstract Background: Paclitaxel is a compound derived from Pacific yew bark that induces various cancer cell apoptosis. However, whether it also has anticancer activities in KOSC3 cells, an oral cancer cell line, is unclear. Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, flow cytometry, and western blotting assays were carried out to assess cell viability, subG1 phase of the cell cycle, and apoptosis-related protein expression, respectively. Results: Our findings indicate that paclitaxel could inhibit cell viability and increase the expression of apoptotic markers, including plasma membrane blebbing and the cleavage of poly ADP-ribose polymerase in KOSC3 cells. Also, the treatment with paclitaxel More > Graphic Abstract

    Paclitaxel induces human KOSC3 oral cancer cell apoptosis through caspase pathways

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