Shaokun Zhang*, Lidi Liu*, Zhenshan Lv*, Qiao Li*, Weiquan Gong*, Hong Wu†
Oncology Research, Vol.25, No.9, pp. 1505-1515, 2017, DOI:10.3727/096504017X14886485417426
Abstract Recent studies suggest that microRNAs (miRNAs) are critical regulators in many types of cancer, including
osteosarcoma. miR-342-3p has emerged as an important cancer-related miRNA in several types of cancers.
However, the functional significance of miR-342-3p in osteosarcoma is unknown. The aims of this study were
to investigate whether miR-342-3p is dysregulated in osteosarcoma and to explore the biological function of
miR-342-3p in regulating cellular processes of osteosarcoma cells. We found that miR-342-3p expression was
significantly decreased in osteosarcoma tissues and cell lines. Overexpression of miR-342-3p inhibits the proliferation, migration, and invasion of osteosarcoma cells. In… More >
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